Tranexamic acid for knee osteotomy recovery
Treatments studied
Part of Bones, joints & muscles clinical trials.
This study tests whether giving tranexamic acid during knee surgery reduces bleeding and improves recovery. It is for people having a specific knee realignment procedure called a high tibial osteotomy.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have knee osteoarthritis that is worse on the inner side of the knee, causing a bow-legged alignment.
- You are scheduled for a medial opening wedge high tibial osteotomy (a surgery to realign your knee).
- You do not have an allergy to tranexamic acid or problems with color vision.
- You have not taken blood thinners within 5 days before surgery, and you do not have a bleeding disorder (platelet count below 150,000).
- You are not pregnant or breastfeeding.
- You do not have inflammatory or infectious arthritis, major nerve problems, or a history of blood clots treated with lifelong blood thinners.
- You have not had a blood clot within the past year, and you do not have a genetic condition that increases clotting risk.
- You are not taking certain medications, including hormonal contraceptives, that could increase clotting risk when combined with tranexamic acid.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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