Ventilator settings for kidney protection in the ICU
Part of Kidney & urinary, Women’s health & pregnancy clinical trials.
This study looks at how different breathing machine settings affect the heart, lungs, and kidneys in critically ill patients. Researchers will adjust ventilator pressure to find the safest level for your kidneys.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 years or older.
- You need to be admitted to the intensive care unit (ICU).
- You must be on a breathing machine (ventilator) and likely to stay on it for at least 2 days.
- Doctors need to be able to see your heart clearly on an ultrasound (echocardiogram) to do the study measurements.
- You cannot be on long-term dialysis for kidney disease.
- You cannot have severe heart valve disease (pulmonary or tricuspid) that would make the ultrasound measurements unreliable.
- You cannot be pregnant.
- You must not be expected to pass away within the next 24 hours.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study looks at how acute kidney injury (a sudden drop in kidney function) affects how well patients can come off a breathing machine. It aims to help doctors better plan breathing trials for patients with kidney issues.
This study compares different ways to support breathing in patients who need a ventilator in the cardiac intensive care unit. It aims to find the best approach for people with certain heart conditions, like cardiogenic shock or heart failure.
This study looks at how different settings on the breathing machine (ventilator) are used for critically ill adults in the ICU. It may help doctors improve care for people who need a breathing tube.
This study tests a new way to guide fluid treatment for people in septic shock who are on a breathing machine. The goal is to see if this method can prevent kidney damage, which is a common complication.
This trial tests whether adjusting the pressure on your breathing machine in a specific way can help protect your kidneys while you're on a ventilator for ARDS. It uses ultrasound to monitor your veins and kidney function.
The trial is studying whether the way a breathing machine affects the kidneys can be improved to prevent kidney damage. It will look at people with severe lung failure who are on a breathing machine to see if they can avoid acute kidney injury.
Hear when a new Acute Kidney Failure trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.