Breathing support settings and kidney health in severe lung failure
Part of Lungs & breathing clinical trials.
This study tests whether adjusting ventilator settings (called PEEP) in patients with severe acute lung failure can improve kidney function and reduce fluid buildup detected by ultrasound. Researchers will monitor how these adjustments affect your kidneys and overall recovery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older
- You have been diagnosed with acute respiratory distress syndrome (ARDS)—severe lung failure requiring a breathing tube
- You have been on a mechanical ventilator (breathing machine) for at least 24 hours
- Your ventilator requires PEEP (breathing pressure support) of at least 5 cmH₂O
- You do not have end-stage kidney disease requiring dialysis or a previous kidney transplant
- You are not pregnant and do not have severe heart valve problems or advanced liver disease
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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