Clinical trials
Acute Kidney Failure clinical trials
Below are recruiting acute kidney failure clinical trials, each written for real people, not researchers. We’re tracking 123 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06881927RecruitingPhase 4
Reducing anti-rejection meds in ICU for kidney transplant patients
This study tests whether quickly reducing your anti-rejection medicines during a life-threatening ICU stay can help your kidneys recover and improve your overall outcome. It is for kidney transplant recipients with septic shock or severe breathing failure.
StrasbourgAges 18 years+ - NCT05325099RecruitingPhase 1/Phase 2
Azacitidine to help prevent kidney injury after heart surgery
This early-phase study tests whether azacitidine (a medication that changes how cells read genes) can lower the risk of acute kidney injury after cardiac surgery, especially in people already at risk along the chronic kidney disease (CKD) pathway. It aims to protect kidney function during the vulnerable period after surgery.
TaipeiAges 20 years+ - NCT07550790Recruiting
Preventing kidney injury during heart failure imaging scans
This study tests whether a specific water-based medication can prevent kidney damage when patients with acute heart failure need a CT scan with contrast dye. The trial focuses on people with mild-to-moderate kidney problems who are hospitalized for fluid buildup in the heart.
Seongnam-si, Gyeonggi-doAges 20 years+ - NCT04334707Recruiting
Study kidney damage in people with long-term diabetes
This study is looking at different kidney health patterns in people with diabetes, especially diabetic kidney disease and people who have not developed kidney damage despite long-term diabetes. It may help researchers understand why kidney problems happen—and what protective factors might prevent them.
Tucson, ArizonaAges 18 years+ - NCT04446858Recruiting
Ultrasound tests to study kidney failure in liver pressure disease
This trial studies whether special non-invasive ultrasound scans can help predict outcomes in people who have both liver-related high blood pressure in the veins (portal hypertension) and kidney failure. It may help doctors choose better monitoring and treatment for this specific combination of problems.
BonnAges 18–100 - NCT04982419RecruitingPhase 2/Phase 3
Remote arm treatment to protect heart and kidneys in heart failure
This trial tests whether a simple “arm cuff” treatment done before a heart artery procedure can help protect the kidneys and the heart in people with congestive heart failure. If it works, it may lower the chance of kidney injury around the time of the scan/stent procedure.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT05247502Recruiting
Study of kidney outcomes after ICU kidney injury
This study follows adults who stay in the ICU for more than 24 hours to see how an episode of acute kidney failure affects kidney health over the long term. Your participation helps researchers understand which ICU patients may need closer kidney monitoring later.
Clermont-FerrandAges 18 years+ - NCT05817539Recruiting
Early circulation-focused care during kidney dialysis in ICU
This trial looks at whether starting dialysis-related care early, aimed at improving blood flow to tissues, can help people in the ICU who have sudden kidney failure. It may help reduce problems related to poor tissue circulation, but it is very specific about ICU illness and current treatments.
AjaccioAges 18 years+ - NCT06006819Recruiting
Acute heart failure with chronic kidney disease study
This trial studies how certain markers in the blood can predict outcomes in people with acute heart failure who also have chronic kidney disease. If you qualify, researchers will follow your health during this hospital stay.
Taipei, Baitou DistrictAges 20–90 - NCT06714409Recruiting
Ultrasound-guided fluid removal in hospitalized heart failure
This study tests whether using ultrasound-guided treatment to reduce fluid buildup in the body can help people hospitalized for worsening heart failure feel better faster. It's for adults admitted with heart failure and high BNP levels.
OsloAges 18 years+ - NCT06921603Recruiting
Ultrasound-guided diuretics for heart failure
This trial tests whether using a bedside ultrasound to guide diuretic treatment improves outcomes in people hospitalized for worsening heart failure. It may help find the right dose of IV diuretics faster.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT07262320Recruiting
Kidney treatment in Latin American ICUs
This study looks at how dialysis (renal replacement therapy) is used for patients in intensive care units (ICUs) with severe acute kidney injury in Latin America. Your participation can help improve care for people with kidney problems.
CochabambaAges 18 years+ - NCT07273838RecruitingPhase 2
SGLT2 inhibitor for acute heart and kidney failure
This study tests whether a medicine called an SGLT2 inhibitor (which lowers blood sugar and helps the kidneys) can improve outcomes for people with acute heart failure and kidney problems. Participation involves taking the study drug or a placebo for a short time.
New Haven, ConnecticutAges 18–85 - NCT07631221Recruiting
Protein Amount in Nutrition for Critically Ill Kidney Patients
This study tests whether different amounts of protein in tube feeding or IV nutrition affect kidney recovery in patients admitted to the intensive care unit (ICU) with kidney injury. The goal is to find the best protein level to help kidneys heal while patients are critically ill.
Buenos Aires, Buenos AiresAges 18 years+ - NCT06987604Enrolling by invitation
Dialysis intensity for high ammonia in liver failure
This trial tests if a higher intensity of continuous dialysis (CRRT) better lowers ammonia levels in patients with liver failure. It aims to find the best approach to reduce brain complications from high ammonia.
Porto Alegre, Rio Grande do SulAges 18 years+ - NCT06463964Enrolling by invitation
Predicting kidney injury in emergency heart failure patients
This study looks at what factors might predict acute kidney injury (sudden kidney damage) in people who come to the emergency room with acute decompensated heart failure (a sudden worsening of heart failure). The goal is to help doctors identify who is at highest risk so they can take steps to protect the kidneys.
SohagAges 18 years+ - NCT05374291Enrolling by invitationPhase 3
Dapagliflozin trial for kidney and heart outcomes in severe CKD
This study tests whether dapagliflozin can improve kidney and heart-related outcomes in people with severe chronic kidney disease (CKD). You would take the study medicine (or a comparison treatment) and be followed to see how your kidneys and heart do over time.
Canberra, Australian Capital TeritoryAges 18 years+ - NCT05285878Enrolling by invitationPhase 2
Fingolimod to protect kidney function after kidney transplant
This trial tests whether fingolimod can reduce kidney scarring and preserve kidney function after a new kidney transplant. It focuses on people who are in the early period after transplant who may be at risk for scarring in the kidney.
Houston, TexasAges 18–65 - NCT06937307RecruitingPhase 2
Droxidopa for low blood pressure in cirrhosis with kidney injury
This trial tests a medication called droxidopa to see if it can raise blood pressure in people with cirrhosis who also have acute kidney injury. If you have low blood pressure and are in the hospital with these conditions, this study may help improve your kidney function.
New York, New YorkAges 18–70 - NCT07682298Recruiting
Measuring leftover fluid in hospitalized heart failure patients
This study looks at how well we can measure leftover fluid in the body in people hospitalized for heart failure with fluid overload. It aims to help doctors better manage treatment and improve recovery.
AarhusAges 18 years+ - NCT05758077Recruiting
SeLective blood-filter trial for acute kidney injury in ICU
This trial tests a special device that filters parts of the blood to calm inflammation in people with severe acute kidney injury in the ICU. It may help improve recovery and reduce complications by “deactivating” certain immune cells.
Birmingham, AlabamaAges 18 years+ - NCT06471621Recruiting
Personalized care to prevent kidney injury after heart surgery
This trial tests whether personalized care can prevent acute kidney injury (sudden kidney damage) after heart or major blood vessel surgery. If you are having planned heart valve repair, bypass, or aortic surgery, you may be able to join.
BernAges 18 years+ - NCT06654193RecruitingPhase 1/Phase 2
Stem cells vs placebo for acute kidney injury
This trial tests whether donor stem cells (HB-adMSCs) can help patients with acute kidney injury from trauma, burns, or crush injuries. It aims to see if the treatment improves kidney function compared to a placebo.
Birmingham, AlabamaAges 18–75 - NCT07236463RecruitingPhase 1/Phase 2
Iron chelator in dialysis fluid for sepsis-related kidney injury
This trial tests if adding an iron chelator (MEX-CD1) to the dialysis fluid can help remove harmful iron from the blood in patients with sepsis-related acute kidney injury who need continuous dialysis. It may reduce damage to the kidneys and other organs.
Nîmes, GardAges 18 years+
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Common questions
- Are there clinical trials for acute kidney failure?
- Yes. Clin2 currently lists 123 recruiting acute kidney failure studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a acute kidney failure trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a acute kidney failure trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.