Pain relief after lumbar fusion surgery
Treatments studied
Part of Bones, joints & muscles, Pain clinical trials.
This study compares two ways of managing pain after lumbar fusion surgery to see which works better and has fewer side effects. One method uses a pain pump with morphine; the other adds a second medicine, clonidine.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 70 years old.
- You are scheduled for a 1- or 2-level lumbar fusion surgery.
- You will stay in the hospital for at least 24 hours after surgery.
- You are generally healthy (classified as ASA I-III by your doctor).
- You speak English.
- You do not have chronic pain requiring high-dose opioids, substance use disorder, serious heart disease, bleeding problems, or other exclusions listed by the study team.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
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This study tests whether giving lidocaine through an IV during and after lumbar fusion surgery can help reduce pain and improve recovery. Lidocaine is a numbing medicine that may decrease pain and the need for other pain drugs.
This study tests whether a special numbing injection (called an erector spinae plane block) given near the spine during surgery can reduce pain after lumbar fusion. If you qualify, you might have less pain and need fewer painkillers after your operation.
This trial compares two different medications (morphine and dexmedetomidine) given through a spinal injection to see which provides better pain relief after lumbar spine surgery. If you qualify, you will receive one of these treatments or a placebo to help manage your pain after the operation.
This study tests a numbing injection near the spine to reduce pain after lumbar fusion surgery. It also adds two medications to make the pain relief last longer and reduce inflammation.
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