Clin2
NCT07848633Worth exploringNot yet recruiting

Subcutaneous treatment for HER2-positive breast cancer before surgery

HER 2 Positive Advanced Breast Cancer

Part of Cancer clinical trials.

This trial tests a treatment for HER2-positive breast cancer given without intravenous (IV) therapy - likely as injections under the skin. It aims to see if this approach is effective before surgery.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
65 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are at least 18 years old and are a woman.
  • You have a new breast cancer diagnosis (Stage II or III) that has not been treated yet.
  • Your tumor is HER2-positive (score 3+ on biopsy).
  • You are able to do daily activities (performance status 0 or 1).
  • Your heart and laboratory tests show adequate organ function.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07739511Recruiting· Phase 1/Phase 2
Oral paclitaxel for HER2-positive breast cancer before surgery

This trial tests an oral form of paclitaxel combined with standard HER2 therapy given before surgery for HER2-positive breast cancer. It aims to find the best dose and see how well it works.

Guiyang, Guizhou
NCT07095023Recruiting
Oral chemo and targeted therapy before breast cancer surgery

This trial tests a combination of an oral chemotherapy pill (paclitaxel) with two targeted antibodies (pertuzumab and trastuzumab) given before surgery for HER2-positive breast cancer. The goal is to shrink the tumor and make surgery more effective.

Beijing, Beijing Municipality
NCT07246317Not yet recruiting· Phase 2
Targeted therapy before surgery for HER2-positive breast cancer

This trial tests a combination of targeted drugs and chemotherapy before surgery for HER2-positive breast cancer. It aims to see if this approach can shrink or eliminate the tumor, making surgery more effective.

Guangzhou, Guangdong
NCT07527806Not yet recruiting· Phase 2
Personalized pre-surgery treatment for HER2-positive breast cancer

This trial tests different combinations of targeted therapy and chemotherapy before surgery for HER2-positive breast cancer. It uses a special PET scan to see how well the treatment is working and to help choose the best treatment plan for each person.

NCT07393425Recruiting· Phase 2
Study of two targeted therapies before surgery for HER2+ breast cancer

This trial tests a combination of two drugs, trastuzumab deruxtecan (SHR-A1811) and pertuzumab, given before surgery to shrink HER2-positive breast cancer. It is for women with stage II or III breast cancer who have not yet had treatment and are in good overall health.

Shanghai, Shanghai Municipality
NCT06441890Recruiting· Phase 2
Personalized chemo before breast cancer surgery

This trial tests whether giving chemotherapy before surgery, guided by the genetic profile of your tumor, can improve outcomes for a specific type of HER2-positive breast cancer. It aims to tailor treatment to each person's cancer biology.

Chicago, Illinois

Hear when a new HER 2 Positive Advanced Breast Cancer trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.