Oral chemo and targeted therapy before breast cancer surgery
Part of Cancer, Skin clinical trials.
This trial tests a combination of an oral chemotherapy pill (paclitaxel) with two targeted antibodies (pertuzumab and trastuzumab) given before surgery for HER2-positive breast cancer. The goal is to shrink the tumor and make surgery more effective.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 75 years old.
- Your breast cancer is HER2-positive (a type that can be treated with targeted drugs).
- Your cancer has not spread to other parts of the body (stage M0).
- You have not had chemotherapy or targeted therapy for this breast cancer yet.
- Your heart, blood, liver, and kidney function are within safe limits (your doctor will check this).
- You are willing to take the study drugs by mouth and have no serious stomach or intestine problems.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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