Clin2
NCT07865871Possibly a fitNot yet recruiting

Inhaled antibiotic for drug-resistant pneumonia after stroke

Ventilator Associated Pneumonia ( VAP)

Part of Infections, Lungs & breathing clinical trials.

This study tests whether adding an inhaled antibiotic (polymyxin) to standard IV antibiotics helps treat a severe lung infection that is resistant to many drugs. It is for people who had a stroke and developed this infection while on a breathing machine. The inhaled drug is delivered directly to the lungs, which might improve treatment and reduce side effects.

Summary written for real people, not researchers, by Clin2.

Phase
Early Phase 1
Enrollment
78 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You must be an adult who had a stroke confirmed by a CT or MRI scan.
  • You must be diagnosed with pneumonia caused by multidrug-resistant bacteria.
  • You must be stable enough to take part and be receiving IV antibiotics.
  • You need to be willing to give consent (or a legal guardian can).
  • You cannot be allergic to colistin, pregnant, have severe kidney disease, or have a weakened immune system.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06819462Recruiting
Inhaled colistin to prevent ventilator pneumonia in brain injury patients

This trial tests whether giving an inhaled antibiotic called colistin can prevent pneumonia in patients with brain injuries who are on ventilators. If effective, it could reduce lung infections and improve recovery.

Nanjing, Jiangsu
NCT06834971Recruiting
Inhaled colistin to prevent pneumonia in ventilated patients

This trial tests if inhaling a medication called colistin can prevent ventilator-associated pneumonia (a lung infection) in patients who are on a breathing machine. It aims to reduce the risk for those at high risk of getting an infection from drug-resistant bacteria.

Jinan, Shandong
NCT06808074Recruiting· Phase 4
Inhaled amikacin to prevent pneumonia in cirrhosis patients on ventilators

This trial tests whether inhaling an antibiotic called amikacin can prevent ventilator-associated pneumonia in patients with severe liver disease (cirrhosis) who are on a breathing machine. If you or your loved one is in the ICU with liver issues and needs a ventilator, this study may help reduce the risk of a serious lung infection.

Hyderabad, Telangana
NCT07203638Enrolling by invitation
Antibiotics to prevent pneumonia in ventilated patients

This trial tests whether giving preventive antibiotics to adults on breathing machines lowers the risk of developing pneumonia during ventilation. It is a double-blind study, meaning neither you nor your doctor will know if you receive the antibiotic or a placebo.

Banhā, Al-Qalyubia
NCT07403474Recruiting· Phase 4
Using rapid testing to guide antibiotic choice in ventilator pneumonia

This trial tests whether using a rapid test to find the exact bacteria causing your pneumonia can help doctors choose the right antibiotics faster, which might improve your recovery. The study compares this approach to usual care in patients on ventilators.

Alès
NCT06907069Enrolling by invitation· Phase 4
Combined treatment for drug-resistant bacteria in lung infections

This trial tests if giving a medication (colistin) both through an IV and as a mist you breathe in works better for lung infections caused by bacteria that are hard to treat with standard antibiotics. It may help patients who have these tough bacteria and are in the hospital.

Ningbo, Z

Hear when a new Ventilator Associated Pneumonia ( VAP) trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.