Symmetric valve expansion after TAVI
Part of Heart & circulation clinical trials.
This trial tests whether expanding the new heart valve in a more symmetric way after TAVI (a procedure to replace a narrowed heart valve) can reduce the risk of blood clots forming on the valve leaflets. It may help keep the new valve working well over time.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 70 years old or older.
- You have severe aortic stenosis (a narrowed heart valve) and are scheduled for a TAVI procedure with a balloon-expandable valve.
- You are not taking blood-thinning medications like warfarin or DOACs (apixaban, rivaroxaban, etc.).
- Your kidney function is adequate (eGFR of 30 or higher).
- You do not have an allergy to iodine-based contrast dye used in imaging.
- You have a tricuspid (normal three-leaflet) aortic valve, not a specific type of bicuspid valve with a calcified raphe.
- During the procedure, your doctor does not expect to need post-dilatation (extra ballooning) for an under-expanded valve or leakage.
- You are willing and able to give written informed consent.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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