Clin2
NCT07875920Possibly a fitNot yet recruiting

Engineered immune cells for advanced solid tumors with KRAS G12V mutation

Advanced Solid CancerPancreatic Ductal Adenocarcinoma (PDAC)Colorectal AdenocarcinomaLung AdenocarcinomaKRAS G12VPancreatic CancerColorectal Cancer

Treatments studied

Part of Cancer, Digestive system, Hormones & metabolism clinical trials.

This trial tests a new treatment made from your own immune cells that are specially trained to attack cancer cells with a specific mutation called KRAS G12V. It is for people with advanced solid tumors who have run out of standard options.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1
Enrollment
66 people
Ages
18 years to 75 years
Study type
Interventional

Who can take part

  • You are between 18 and 75 years old
  • You have a specific immune system marker called HLA-A*11:01
  • Your tumor has a KRAS G12V mutation
  • You have at least one tumor that can be measured on scans
  • You are physically active (ECOG 0-1) and expected to live more than 3 months
  • You have not had certain treatments recently, and you do not have severe autoimmune disease or active infections

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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