Hidden knee fluid and its role in knee osteoarthritis
Part of Bones, joints & muscles clinical trials.
This study looks at whether small amounts of fluid in the knee joint (found on an MRI, not visible on a regular exam) affect pain and function in people with knee osteoarthritis. If you have knee osteoarthritis and some knee pain, this study may help improve understanding of your condition.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 40 and 80 years old.
- You have been diagnosed with knee osteoarthritis (confirmed by X-ray showing moderate to severe changes).
- You have pain in the knee that the study will evaluate.
- You are able to contract your thigh muscle (quadriceps) on purpose and able to do the 30-second chair stand test (standing up and sitting down repeatedly).
- You do not have other joint diseases like rheumatoid arthritis, gout, or an active joint infection.
- You have not had a knee injection in the past 3 months, major knee surgery, or a knee injury in the past 3 months.
- You are not pregnant and do not have other conditions that would make the chair stand test unsafe or hard to do.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study looks at how knee osteoarthritis (a common condition where the cushioning in the knee joint wears down) affects physical function, even when people report similar levels of pain. It aims to understand why some people with the same pain might have more difficulty with daily activities, which could lead to better targeted treatments.
This study looks at how knee ligament stiffness changes in people with knee osteoarthritis and compares it to healthy volunteers. It may help find better ways to treat knee pain and stiffness.
This study uses ultrasound imaging to evaluate knee osteoarthritis in people over 30 with painful knees. It aims to better understand how the condition appears on imaging.
This study looks at two substances in your blood that might be linked to knee osteoarthritis. It may help doctors better understand joint damage and could lead to better ways to track the disease.
This research study uses advanced imaging (PET and MRI scans) to better understand osteoarthritis in the front of the knee, where the kneecap meets the thighbone. You'll help researchers learn how to detect and track this condition earlier.
This study looks at certain enzymes in the blood of women with knee osteoarthritis. It may help doctors understand how arthritis works and could lead to better treatments.
Hear when a new Knee Osteoarthritis trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.