How psilocybin dose affects its mind-altering effects
This trial studies how different doses of psilocybin (the active ingredient in magic mushrooms) affect its intoxicating and potentially habit-forming effects. You will receive the drug in a controlled setting, and the results may help guide safe use in the future.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be at least 21 years old.
- You must be in generally good health, confirmed by a physical exam, blood tests, and a psychiatric evaluation.
- You must have used psilocybin (magic mushrooms) at least once in your life, but not in the past month.
- You must not use any psychoactive drugs (other than nicotine, alcohol, caffeine, or cannabis) in the past month, and you must have a negative urine test for illicit drugs (except cannabis) and a zero breath alcohol test before sessions.
- You cannot be pregnant or breastfeeding, and you cannot have donated blood in the past 30 days.
- Your body mass index (BMI) must be between 18 and 36.
- You must not have a history of serious medical conditions (like high blood pressure or epilepsy), current psychiatric conditions, or a first-degree relative with psychotic disorder or bipolar 1 disorder.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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