Clinical trials · California
Adolescent clinical trials in California
We’re tracking 102 recruiting adolescent studies with a site in California — including Early Phase 1, Phase 1, Phase 2 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies in California
- NCT07065669Recruiting
TMS for teens with OCD
This study tests if transcranial magnetic stimulation (a non-invasive brain stimulation technique) can help treat obsessive-compulsive disorder in adolescents aged 13-17. It aims to see if this treatment can reduce OCD symptoms when added to stable medications or therapy.
San Francisco, CaliforniaAges 13–17 - NCT07049575RecruitingPhase 1
Ruxolitinib cream study for hidradenitis suppurativa
This study tests a cream called ruxolitinib for people with hidradenitis suppurativa (HS). The goal is to see how much of the cream is absorbed when it's applied to a large area of the body.
Fountain Valley, CaliforniaAges 12–75 - NCT07025720Recruiting
Brain stimulation for depression and suicide risk in young people
This study tests a new type of brain stimulation called TMS (transcranial magnetic stimulation) for young people ages 15-25 who are having serious depression and suicidal thoughts. The goal is to see if this treatment can help reduce risk and improve mood.
Sacramento, CaliforniaAges 15–25 - NCT06988605Recruiting
Nemolizumab for teens and adults with moderate-to-severe eczema
This study looks at how well nemolizumab works in everyday practice for people with moderate-to-severe atopic dermatitis (eczema). It helps researchers understand the real-world benefits and safety of this treatment.
Corona, CaliforniaAges 12 years+ - NCT06979453RecruitingPhase 3
A study of deucravacitinib for teens with plaque psoriasis
This trial tests an investigational oral medication called deucravacitinib for teenagers (adolescents) with moderate to severe plaque psoriasis. It aims to see if the drug is safe and works well.
Fountain Valley, CaliforniaAges 12–17 - NCT05295680RecruitingPhase 2
Oral hymecromone for primary sclerosing cholangitis
This trial tests whether taking hymecromone by mouth can improve primary sclerosing cholangitis (a liver/bile duct condition). It may help by targeting inflammation and bile duct problems, especially in people who are stable on other medicines.
Redwood City, CaliforniaAges 14–75 - NCT05563649Recruiting
Online guided family self-help for teens with anorexia
This trial tests whether an online, guided “self-help” program that involves the family helps teens with anorexia recover better than usual care. It aims to improve eating and reduce anorexia symptoms while being delivered from home.
Stanford, CaliforniaAges 12–18 - NCT06900595RecruitingPhase 2
Cabozantinib with immunotherapy for advanced adrenal cancer
This trial tests adding the targeted drug cabozantinib to the immunotherapy cemiplimab for people with advanced adrenocortical carcinoma that cannot be removed by surgery or has spread. It checks if the combination works better than cabozantinib alone.
La Jolla, CaliforniaAges 12 years+ - NCT06898788RecruitingEarly Phase 1
Probiotics for depression in teens and young adults
This study tests whether a probiotic supplement can help improve depression in young people who are already taking an SSRI antidepressant. If you join, you will take a probiotic or placebo for several weeks and have your mood and brain activity checked.
San Francisco, CaliforniaAges 15–24 - NCT06850805RecruitingPhase 3
Nasal spray for teens with chronic sinusitis without polyps
This study tests a new nasal spray (OPN-375) for teens aged 12–17 with chronic sinusitis but without nasal polyps. It aims to see if the spray improves symptoms like congestion and runny nose.
Los Angeles, CaliforniaAges 12–17 - NCT06822426RecruitingPhase 3
Catheter lock solution to prevent bloodstream infections in patients on IV nutrition
This study tests a catheter lock solution called DefenCath (taurolidine and heparin) against a standard heparin lock to see if it reduces central line bloodstream infections in people receiving IV nutrition (total parenteral nutrition) for more than 3 months.
Los Angeles, CaliforniaAges 12 years+ - NCT06821178Recruiting
My life and my experiences study for teens
This study looks at the life experiences of teenagers ages 12 to 18, comparing those who have had contact with social services or dependency court with those who have always lived with a parent. It helps researchers understand how different backgrounds affect well-being.
Irvine, CaliforniaAges 12–18 - NCT06699849RecruitingPhase 2
CSL889 for sickle cell pain crisis
This trial tests a new medicine, CSL889, for people with sickle cell disease who are currently having a pain crisis (vaso-occlusive crisis). The goal is to see if it safely helps reduce the pain and speed recovery.
Oakland, CaliforniaAges 12 years+ - NCT06699251Recruiting
Brief chat with your doctor about alcohol or cannabis for teens
This study tests whether a short, one-time conversation with a primary care provider can help teens who are at risk for alcohol or cannabis use. It's designed for young people ages 12–17 who get care at two specific health systems.
Commerce, CaliforniaAges 12–19 - NCT06689085RecruitingPhase 3
Testosterone replacement study for adolescent boys with low testosterone
This trial tests a testosterone injection (XYOSTED) to see if it's safe and effective for replacing testosterone in teenage boys who have low levels due to a known medical condition. It lasts 52 weeks, with an optional 2-year follow-up.
Los Angeles, CaliforniaAges 12–17 - NCT06679881Enrolling by invitationPhase 3
Daily oral tablet to prevent hereditary angioedema attacks
This study tests a daily oral tablet called deucrictibant to see if it can prevent swelling attacks in people with hereditary angioedema (HAE). If you join, you will take the study drug for a longer period and track your symptoms in a diary.
San Diego, CaliforniaAges 12 years+ - NCT06672939RecruitingPhase 3
Orforglipron for Weight Loss in Teens
This study tests a once-daily pill (orforglipron) to help adolescents with obesity or overweight plus related health problems lose weight. It offers a new option for teens who have struggled to lose weight with diet and exercise alone.
Oxnard, CaliforniaAges 12–17 - NCT06574321Enrolling by invitation
Wrap It Up: A school program for healthy relationships
This study tests a school-based program called 'Wrap It Up' that teaches teens about healthy relationships and safer sex. The program is done in groups over two years, and the study compares doing it first versus later.
Scotts Valley, CaliforniaAges 16–19 - NCT06525064Recruiting
Health-E You app study for teen guys
This study tests a health app designed for teen guys who have had vaginal or anal sex. It aims to see if the app can help with sexual health decisions and education.
Oakland, CaliforniaAges 13–21 - NCT06513962RecruitingPhase 3
Triptorelin to protect ovaries in young women with cancer
This study tests whether a medicine called triptorelin can protect the ovaries in young women and teens receiving strong chemotherapy for cancer. If you are newly diagnosed with a cancer (other than breast cancer) and are about to get certain chemotherapy drugs, this trial may help preserve your fertility.
Los Angeles, CaliforniaAges Up to 39 years - NCT06458920Recruiting
How friends help teens manage emotions
This study looks at how teens and young adults learn to manage their emotions. If you fit the age range and are healthy enough for an MRI, you may help us understand how social situations affect emotion regulation.
Los Angeles, CaliforniaAges 13–25 - NCT06444360Recruiting
Program to reduce stimulant use and risky sex in young adults
This study tests a program to help sexually active young adults reduce stimulant use and risky sexual behavior. It involves online coaching sessions, and you can join from home if you have a private space and video chat access.
Los Angeles, CaliforniaAges 16–24 - NCT06439082RecruitingPhase 3
Crizanlizumab for sickle cell pain crises
This trial tests whether crizanlizumab can reduce painful sickle cell crises (called vaso-occlusive crises or VOCs) in people with sickle cell disease who have frequent crises. It may be an option for those who still have crises despite current treatments.
Orange, CaliforniaAges 12–100 - NCT06410209RecruitingPhase 2
Walking Juntos: Smartphone program to help Hispanic cancer survivors be active
This study will test if a smartphone program and social media group can help Hispanic/Latino teens and young adults who had childhood cancer become more physically active. You would wear a Fitbit and use a phone app with culturally tailored tips and support.
Downey, CaliforniaAges 15–20
Where these studies are running in California
Institutions with a site for the recruiting adolescent studies listed above.
- Children's Hospital of Orange County · 3 studies
- Rady Children's Hospital · 3 studies
- University of California, Los Angeles · 3 studies
- City of Hope · 2 studies
- Kaiser Permanente-Oakland · 2 studies
- Mattel Children's Hospital UCLA · 2 studies
- UC San Diego Moores Cancer Center · 2 studies
- UCSF Benioff Children's Hospital Oakland · 2 studies
What taking part in a adolescent study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Adolescent trials in other states
Common questions
- Are there adolescent clinical trials in California?
- Yes. We're currently tracking 102 recruiting adolescent studies with a site in California, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a adolescent study in California?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in California to take part?
- Not necessarily. These studies have a site in California, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a adolescent trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New adolescent studies open in California regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.