Clinical trials · California
Adolescent clinical trials in California
We’re tracking 102 recruiting adolescent studies with a site in California — including Phase 1, Phase 1/Phase 2, Phase 2 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies in California
- NCT06486688Recruiting
Virtual program to help teens with substance use risk
This trial tests a virtual program integrated into pediatric check-ups to help teens at risk for alcohol or drug problems. It aims to identify teens who may need extra support and connect them with helpful resources.
Pleasanton, CaliforniaAges 12–17 - NCT07561827RecruitingPhase 3
Nerve Block for Pain After Spine Surgery in Teens
This trial tests whether a numbing injection around the spine muscles (erector spinae plane block) reduces pain and the need for strong pain medications after back surgery for scoliosis in teenagers. The goal is to help young patients recover more comfortably.
San Francisco, CaliforniaAges 10–18 - NCT07525843Recruiting
Well-being education program for teens with heart disease
This study tests whether a special education program about managing emotions and stress helps teenagers with moderate-to-severe congenital heart disease (a heart condition from birth) feel better and cope with their condition. Participants attend sessions and complete surveys over time.
Stanford, CaliforniaAges 12–17 - NCT07406087Recruiting
Navigation support for young adults after cancer
This study tests a navigation program to help cancer survivors ages 21-45 get the follow-up care they need. It may be a good fit if you were diagnosed with certain cancers as a teen or young adult.
Pasadena, CaliforniaAges 21–45 - NCT07220343Recruiting
Using phones and watches to check on teens and young adults with cancer
This study uses your smartphone and a smartwatch to track your daily activity and mood, helping researchers learn how to better support teens and young adults with cancer. It may help improve mental health care for people your age dealing with cancer.
Palo Alto, CaliforniaAges 10–25 - NCT07035418Recruiting
Young adults' role in cancer care decisions
This study looks at how much young people with cancer (ages 15–29) want to be involved in making decisions about their care. It's for those currently on treatment, at end of life, or who finished treatment up to a year ago.
Palo Alto, CaliforniaAges 15–29 - NCT06920940Recruiting
Ketogenic diet for bipolar disorder in teens
This study tests whether a ketogenic diet (a very low-carb, high-fat diet) can help teens with bipolar disorder who are currently feeling depressed or have mixed symptoms. Participants will receive medical and dietitian support while trying the diet for up to 12 weeks.
Los Angeles, CaliforniaAges 12–21 - NCT06783309RecruitingPhase 1/Phase 2
Testing CNP-103 for newly diagnosed type 1 diabetes
This trial tests a new study drug called CNP-103 for people ages 12-35 who were recently diagnosed (within 6 months) with stage 3 type 1 diabetes. The goal is to see if the drug can help preserve the body's ability to make some insulin, potentially slowing the need for more insulin shots.
Newport Beach, CaliforniaAges 12–35 - NCT06439277RecruitingPhase 3
Tirzepatide for teens with obesity and related health problems
This study tests a medication called tirzepatide (a once-weekly injection) to help teenagers with obesity and related health conditions lose weight. It aims to see if the drug is safe and effective for this age group.
Sacramento, CaliforniaAges 12–17 - NCT06365892Recruiting
Open-label placebo for pain after scoliosis surgery
This trial tests whether taking a placebo pill that you know is a placebo (open-label placebo) can help reduce pain after spinal fusion surgery for scoliosis. It compares the placebo to standard care in adolescents aged 11-17.
San Francisco, CaliforniaAges 10–18 - NCT04110756Recruiting
Program to help teens change health behaviors
This study tests a program designed to help teens make healthier choices. It’s for teens who are 15–17 and are currently drinking alcohol, who come to specific UCSF pediatric check-up visits.
San Francisco, CaliforniaAges 15–17 - NCT05329441Recruiting
Testing an anti-depression medicine for threat-related brain changes in teens
This trial studies how fluoxetine or escitalopram (anti-depression medicines) may affect brain systems involved in feeling threatened and staying anxious when you have depression. It also uses brain scanning and blood tests to measure these changes.
Los Angeles, CaliforniaAges 14–21 - NCT06254768Recruiting
Continuous glucose monitors for kids with obesity
This study tests if using a continuous glucose monitor (CGM), a small device that tracks blood sugar, can help children and teens with obesity understand their body better and improve their health.
Los Angeles, CaliforniaAges 10–21 - NCT07723924RecruitingPhase 2
Plecanatide for constipation in children and teens
This study tests a new medicine called plecanatide for children and teens with functional constipation. It aims to see if it helps improve bowel movements compared to a placebo (a pill with no medicine).
Anaheim, CaliforniaAges 6–17 - NCT02434003Recruiting
Test a new way to predict scoliosis curve progression
This study follows adolescents with idiopathic scoliosis to see how well a new predictive model estimates whether the spinal curve will get worse over time. It may help doctors plan monitoring and treatment more accurately for young people with scoliosis.
San Diego, CaliforniaAges 10–15 - NCT07746921Recruiting
Smart inhaler and remote asthma care for teens with intellectual disabilities
This study tests a smart inhaler and a phone app to help teenagers with mild-to-moderate intellectual or developmental disabilities manage their asthma at home. It aims to see if this technology improves asthma control and makes it easier for families to track medication use.
Los Angeles, CaliforniaAges 10–17 - NCT07660198RecruitingPhase 3
Pneumonia vaccine catch-up study for kids and teens
This trial tests a catch-up pneumococcal vaccine for children and adolescents who may have missed some doses. It aims to see how safe and effective the vaccine is in healthy kids aged 15 months to 17 years.
Fair Oaks, CaliforniaAges 1.3 years–17 years - NCT07650916RecruitingPhase 3
A study of two ultra-long-acting HIV shots
This trial tests a new ultra-long-acting injectable combination of cabotegravir and rilpivirine for people with HIV who already have the virus under control. It aims to see if these shots can keep the virus suppressed with fewer doses.
Los Angeles, CaliforniaAges 12 years+ - NCT07575308RecruitingPhase 2
ALN-6400 for Heavy Bleeding in von Willebrand Disease
This trial tests a new medicine called ALN-6400 in teenage and adult women with von Willebrand disease (a blood clotting condition) who experience heavy menstrual bleeding. The goal is to see if this treatment can reduce bleeding and improve quality of life.
Orange, CaliforniaAges 16–45 - NCT07540780Recruiting
Social media support groups to help teens quit vaping
This study tests whether online support groups on social media can help teenagers stop vaping. You'd join a group with other teens your age working toward the same goal, with support from trained peer mentors.
San Francisco, CaliforniaAges 13 years+ - NCT07476183RecruitingPhase 1
Testing APR-2020 for RPS19-deficient Diamond-Blackfan Anemia
This trial is testing a new treatment called APR-2020 for children and young adults with a specific type of Diamond-Blackfan Anemia (caused by a change in the RPS19 gene). The goal is to see if this treatment is safe, tolerable, and can help reduce the need for blood transfusions.
Stanford, CaliforniaAges 2–25 - NCT06783101Recruiting
Smart Inhaler for Teens with Intellectual Disabilities and Asthma
This study tests a 'smart' inhaler that tracks when and how your child uses their asthma medicine. The goal is to help teens with intellectual or developmental disabilities manage asthma better at home.
Los Angeles, CaliforniaAges 10–17 - NCT07456033RecruitingPhase 3
Depemokimab for adults and teens with type 2 asthma
This study tests a new medicine called depemokimab, given as an injection, to see if it can reduce asthma attacks in people with a specific type of asthma (type 2 high). If you have had asthma for several years and have had recent attacks despite using regular inhalers, this trial might be an option for you.
Newport Beach, CaliforniaAges 12 years+ - NCT07424404RecruitingPhase 3
Long-term safety study of a medication for psychiatric disorders in children and teens
This study tests a combination medicine (xanomeline and trospium chloride) to see if it is safe and tolerable over a longer period for children and adolescents with psychiatric disorders, especially those with autism-related irritability. It may help families understand if this treatment can be used beyond the initial study period.
Anaheim, CaliforniaAges 5–17
Where these studies are running in California
Institutions with a site for the recruiting adolescent studies listed above.
- Children's Hospital Los Angeles · 3 studies
- University of California, San Francisco · 3 studies
- GSK Investigational Site · 2 studies
- Stanford University · 2 studies
- Advanced Research Center (ARC)
- Advanced Research Center Inc.
- Apex Research Group
- Center for Clinical Trials, LLC
What taking part in a adolescent study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Adolescent trials in other states
Common questions
- Are there adolescent clinical trials in California?
- Yes. We're currently tracking 102 recruiting adolescent studies with a site in California, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a adolescent study in California?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in California to take part?
- Not necessarily. These studies have a site in California, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a adolescent trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New adolescent studies open in California regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.