Clinical trials · California
Adolescent clinical trials in California
We’re tracking 105 recruiting adolescent studies with a site in California — including Phase 1, Phase 2 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies in California
- NCT07355296RecruitingPhase 2
Testing BI 764198 in adults and teens with kidney disease
This study tests an investigational drug (BI 764198) in adults and teens with different types of kidney disease. The goal is to see if the drug can help slow kidney damage. You may be able to join if your kidney function is at a certain level, you are on stable blood pressure medications, and you haven't had recent strong immune treatments.
Glendale, CaliforniaAges 12 years+ - NCT07456033RecruitingPhase 3
Depemokimab for adults and teens with type 2 asthma
This study tests a new medicine called depemokimab, given as an injection, to see if it can reduce asthma attacks in people with a specific type of asthma (type 2 high). If you have had asthma for several years and have had recent attacks despite using regular inhalers, this trial might be an option for you.
Newport Beach, CaliforniaAges 12 years+ - NCT07276724RecruitingPhase 3
Study of GB-0895 for severe uncontrolled asthma
This trial tests an add-on medicine called GB-0895 for people with severe asthma that is not well controlled with current treatments. It aims to see if adding this drug can reduce asthma attacks and improve breathing.
Northridge, CaliforniaAges 12–80 - NCT07359846RecruitingPhase 3
Study of GB-0895 for severe uncontrolled asthma in adults and teens
This trial tests an add-on treatment called GB-0895 for people with severe asthma that is not well controlled with current medications. It aims to see if adding this drug can reduce asthma attacks and improve lung function.
Bakersfield, CaliforniaAges 12–80 - NCT06699849RecruitingPhase 2
CSL889 for sickle cell pain crisis
This trial tests a new medicine, CSL889, for people with sickle cell disease who are currently having a pain crisis (vaso-occlusive crisis). The goal is to see if it safely helps reduce the pain and speed recovery.
Oakland, CaliforniaAges 12 years+ - NCT06679140RecruitingPhase 3
Study of Ibuzatrelvir for COVID-19 in high-risk patients
This trial tests if a new medicine called ibuzatrelvir can help people with COVID-19 who have certain health risks avoid severe illness. It is for patients who cannot or choose not to take another COVID-19 pill called Paxlovid.
Bakersfield, CaliforniaAges 12 years+ - NCT04649242RecruitingPhase 3
Migraine pain relief study for kids and teens
This trial studies a medicine for stopping a migraine attack in children and teens. It may help families understand which treatment works best during acute (during-attack) migraine pain.
Anaheim, CaliforniaAges 6–17 - NCT07650916RecruitingPhase 3
A study of two ultra-long-acting HIV shots
This trial tests a new ultra-long-acting injectable combination of cabotegravir and rilpivirine for people with HIV who already have the virus under control. It aims to see if these shots can keep the virus suppressed with fewer doses.
Bakersfield, CaliforniaAges 12 years+ - NCT07575308RecruitingPhase 2
ALN-6400 for Heavy Bleeding in von Willebrand Disease
This trial tests a new medicine called ALN-6400 in teenage and adult women with von Willebrand disease (a blood clotting condition) who experience heavy menstrual bleeding. The goal is to see if this treatment can reduce bleeding and improve quality of life.
Los Angeles, CaliforniaAges 16–45 - NCT06386198Recruiting
Health Advocate for Young Liver Transplant Patients
This study tests a program that helps young adults with a liver transplant prepare to move from a children’s hospital to an adult hospital. It aims to provide extra support for people who also have social needs like trouble getting enough food.
San Francisco, CaliforniaAges 18–25 - NCT06979453RecruitingPhase 3
A study of deucravacitinib for teens with plaque psoriasis
This trial tests an investigational oral medication called deucravacitinib for teenagers (adolescents) with moderate to severe plaque psoriasis. It aims to see if the drug is safe and works well.
Fountain Valley, CaliforniaAges 12–17 - NCT05999994RecruitingPhase 2
Testing new drugs for children and young adults with cancer
This trial tests several experimental drugs for children and young adults with cancer. It aims to find safe and effective treatments by matching participants to one of several drug studies based on their cancer type and health.
Los Angeles, CaliforniaAges 1–39 - NCT07080905RecruitingPhase 3
Gene therapy for teens with severe hemophilia B
This trial tests a single dose of CSL222, a gene therapy, in adolescent boys with severe or moderately severe hemophilia B. The goal is to see if it can reduce or eliminate the need for regular factor IX infusions.
Orange, CaliforniaAges 11.5 years–17.2 years - NCT07207876Recruiting
Study of two antibiotics during pregnancy
This study looks at two antibiotics given during pregnancy: ceftriaxone (given as a shot or IV) for infections other than syphilis, and benzathine penicillin G (given as a shot) for syphilis. The goal is to learn more about how these medicines affect pregnant women and their babies.
Los Angeles, CaliforniaAges Any age - NCT07290803Recruiting
Atopic dermatitis treatment registry for teens and adults
This study is a long-term registry for adolescents and adults with atopic dermatitis (eczema) who are starting or switching to a systemic medication (a drug that works throughout the body). It will track how these treatments work in real life and how patients feel over time.
Bakersfield, CaliforniaAges 12 years+ - NCT06458920Recruiting
How friends help teens manage emotions
This study looks at how teens and young adults learn to manage their emotions. If you fit the age range and are healthy enough for an MRI, you may help us understand how social situations affect emotion regulation.
Los Angeles, CaliforniaAges 13–25 - NCT06273137Recruiting
Positive affect treatment for teens with early adversity
This trial tests a treatment designed to improve positive emotions in adolescents who have experienced stressful early life events. It may help your teen build resilience and emotional wellbeing.
Irvine, CaliforniaAges 12–16 - NCT05235867Recruiting
Secretin to help teens with anorexia during refeeding
This trial studies whether secretin can help the body during “refeeding,” the careful process of restarting nutrition in people hospitalized for restrictive-type anorexia nervosa. It compares participants with very high vs very low urine output during refeeding to see if responses differ.
Los Angeles, CaliforniaAges 13–24 - NCT00903110Recruiting
Long-term safety registry for Increlex in children
This study is a registry that follows children and teens with severe IGF-1 deficiency who use Increlex (or specific GH gene deletion situations) to better track long-term safety and effectiveness. You would likely join if your child is already starting or planning Increlex and is not in other growth-related drug trials.
Orange, CaliforniaAges 2–18 - NCT06850805RecruitingPhase 3
Nasal spray for teens with chronic sinusitis without polyps
This study tests a new nasal spray (OPN-375) for teens aged 12–17 with chronic sinusitis but without nasal polyps. It aims to see if the spray improves symptoms like congestion and runny nose.
Orange, CaliforniaAges 12–17 - NCT07199465RecruitingPhase 1
Letermovir for children after a kidney transplant
This study tests an oral antiviral medication called letermovir to see if it safely prevents CMV (a common virus) in children who have recently had a kidney transplant. It's for children ages typically 4 weeks to about a year post-transplant, with stable kidney function and no current CMV infection.
Los Angeles, CaliforniaAges Up to 17 years - NCT06410209RecruitingPhase 2
Walking Juntos: Smartphone program to help Hispanic cancer survivors be active
This study will test if a smartphone program and social media group can help Hispanic/Latino teens and young adults who had childhood cancer become more physically active. You would wear a Fitbit and use a phone app with culturally tailored tips and support.
Downey, CaliforniaAges 15–20 - NCT06444360Recruiting
Program to reduce stimulant use and risky sex in young adults
This study tests a program to help sexually active young adults reduce stimulant use and risky sexual behavior. It involves online coaching sessions, and you can join from home if you have a private space and video chat access.
Los Angeles, CaliforniaAges 16–24 - NCT07125001Recruiting
Mango study for Hispanic/Latino teens' health
This study looks at whether eating mango every day for 12 weeks can improve gut health and heart health in Hispanic/Latino teens who are overweight. Participants will be asked to eat a mango product and take daily photos.
Davis, CaliforniaAges 12–19
Where these studies are running in California
Institutions with a site for the recruiting adolescent studies listed above.
- University of California, Los Angeles (UCLA) · 6 studies
- Children's Hospital of Orange County · 4 studies
- Breathe Clear Institute for Sinus and Allergy Relief · 2 studies
- Center for Dermatology Clinical Research · 2 studies
- Dermatology Research Associates · 2 studies
- GSK Investigational Site · 2 studies
- Miller Children's and Women's Hospital Long Beach · 2 studies
- Northridge Clinical Trials · 2 studies
What taking part in a adolescent study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Adolescent trials in other states
Common questions
- Are there adolescent clinical trials in California?
- Yes. We're currently tracking 105 recruiting adolescent studies with a site in California, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a adolescent study in California?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in California to take part?
- Not necessarily. These studies have a site in California, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a adolescent trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New adolescent studies open in California regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.