Clinical trials · Ohio
Adolescent clinical trials in Ohio
We’re tracking 66 recruiting adolescent studies with a site in Ohio — including Phase 1, Phase 1/Phase 2, Phase 2, Phase 2/Phase 3 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies in Ohio
- NCT07133308RecruitingPhase 3
Study of deuruxolitinib for teens with severe alopecia areata
This study tests an investigational oral medication (deuruxolitinib) for adolescents with severe alopecia areata (hair loss). It aims to see if it can help hair regrow safely.
Mason, OhioAges 12–17 - NCT07089121RecruitingPhase 1/Phase 2
Descartes-08 for young people with autoimmune diseases
This trial tests a new therapy called Descartes-08 for children, teens, and young adults with autoimmune conditions like lupus, myasthenia gravis, or dermatomyositis. It aims to see if it can help control moderate disease that hasn't responded well enough to other treatments.
Cincinnati, OhioAges 12 years+ - NCT07058077RecruitingPhase 2/Phase 3
Study of oral cholesterol-lowering pill in children with HeFH
This study tests an experimental daily pill (enlicitide decanoate) that lowers LDL ('bad') cholesterol in children and teens with a genetic condition called heterozygous familial hypercholesterolemia (HeFH). It aims to see if this medicine can safely help reduce their high cholesterol levels.
Cincinnati, OhioAges 6–17 - NCT07049575RecruitingPhase 1
Ruxolitinib cream study for hidradenitis suppurativa
This study tests a cream called ruxolitinib for people with hidradenitis suppurativa (HS). The goal is to see how much of the cream is absorbed when it's applied to a large area of the body.
Columbus, OhioAges 12–75 - NCT06988605Recruiting
Nemolizumab for teens and adults with moderate-to-severe eczema
This study looks at how well nemolizumab works in everyday practice for people with moderate-to-severe atopic dermatitis (eczema). It helps researchers understand the real-world benefits and safety of this treatment.
Dayton, OhioAges 12 years+ - NCT06979453RecruitingPhase 3
A study of deucravacitinib for teens with plaque psoriasis
This trial tests an investigational oral medication called deucravacitinib for teenagers (adolescents) with moderate to severe plaque psoriasis. It aims to see if the drug is safe and works well.
Canton, OhioAges 12–17 - NCT06910943RecruitingPhase 2/Phase 3
Choline injection for adolescents and adults with intestinal failure on long-term parenteral support
This study tests whether a choline injection can help people with intestinal failure who need long-term intravenous nutrition (parenteral support). It may improve liver health and reduce complications from not getting enough choline through food.
Cleveland, OhioAges 12 years+ - NCT06900595RecruitingPhase 2
Cabozantinib with immunotherapy for advanced adrenal cancer
This trial tests adding the targeted drug cabozantinib to the immunotherapy cemiplimab for people with advanced adrenocortical carcinoma that cannot be removed by surgery or has spread. It checks if the combination works better than cabozantinib alone.
Columbus, OhioAges 12 years+ - NCT06854991Enrolling by invitation
Virtual reality for managing pain in healthy kids
This study tests if virtual reality can help distract children and teenagers from the feeling of pain. It could show that VR is a helpful tool for managing pain without medicine.
Columbus, OhioAges 6–17 - NCT06822426RecruitingPhase 3
Catheter lock solution to prevent bloodstream infections in patients on IV nutrition
This study tests a catheter lock solution called DefenCath (taurolidine and heparin) against a standard heparin lock to see if it reduces central line bloodstream infections in people receiving IV nutrition (total parenteral nutrition) for more than 3 months.
Cleveland, OhioAges 12 years+ - NCT06699849RecruitingPhase 2
CSL889 for sickle cell pain crisis
This trial tests a new medicine, CSL889, for people with sickle cell disease who are currently having a pain crisis (vaso-occlusive crisis). The goal is to see if it safely helps reduce the pain and speed recovery.
Cincinnati, OhioAges 12 years+ - NCT03859297Recruiting
Testing how rumination changes in depressed teens
This study looks at what changes in “rumination” (repetitive worrying/thinking about negative thoughts) in teens with depression, and how those changes relate to recovery. It’s for ages 14–17 who have had major depression and meet specific screening and medical rules.
Columbus, OhioAges 14–17 - NCT06670066Recruiting
Trial of let's talk birth control
This trial tests a program to help teens and young adults learn about birth control options during regular health visits. It may help you find the right method for your needs.
Mentor, OhioAges 15–24 - NCT06552286Recruiting
Study of STRW-T program for autistic teens in 11th and 12th grade
This trial tests the STRW-T program to help autistic high school students improve daily living skills. It is designed for teens who are in their last two years of high school or deferring graduation.
Cincinnati, OhioAges 15–21 - NCT06525064Recruiting
Health-E You app study for teen guys
This study tests a health app designed for teen guys who have had vaginal or anal sex. It aims to see if the app can help with sexual health decisions and education.
Cincinnati, OhioAges 13–21 - NCT06513962RecruitingPhase 3
Triptorelin to protect ovaries in young women with cancer
This study tests whether a medicine called triptorelin can protect the ovaries in young women and teens receiving strong chemotherapy for cancer. If you are newly diagnosed with a cancer (other than breast cancer) and are about to get certain chemotherapy drugs, this trial may help preserve your fertility.
Akron, OhioAges Up to 39 years - NCT06476886Recruiting
Comparing two hospital units for teens in crisis
This trial tests a new way to help teenagers who are in a mental health crisis with suicidal thoughts. It compares two different hospital units to see which one works better for teens and their families.
Columbus, OhioAges 12–17 - NCT06454136Enrolling by invitation
App-based support for teens after a suicide attempt
This trial tests a mobile app designed to help teenagers who have recently been hospitalized after a suicide attempt or serious suicidal thoughts. The goal is to see if the app can provide extra support and reduce future suicide attempts.
Cincinnati, OhioAges 13–17 - NCT06408259RecruitingPhase 3
Comparing ozanimod and fingolimod for children with MS
This study compares two oral medications, ozanimod and fingolimod, to see which one works better and is safer for children and teenagers with relapsing-remitting MS. Both drugs help reduce MS attacks and slow down the disease.
Cincinnati, OhioAges 10–17 - NCT06379789RecruitingPhase 1/Phase 2
Gene therapy for severe hemophilia B
This trial tests a new gene therapy (REGV131-LNP1265) that aims to let your body produce its own factor IX, reducing or stopping the need for regular infusions. It is for children and adults with severe hemophilia B who are already using factor IX replacement therapy.
Columbus, OhioAges 2 years+ - NCT06350409Recruiting
Opioid use after surgery in teens
This study looks at how teens aged 12–17 use opioids after a scheduled surgery. It aims to understand outcomes and help improve pain management.
Cincinnati, OhioAges 12–17 - NCT06328608RecruitingPhase 2/Phase 3
PRX-102 for children with Fabry disease
This study tests a new enzyme replacement therapy called PRX-102 for children with Fabry disease. It aims to see if the drug is safe and helps manage symptoms like pain and eye or skin changes.
Cincinnati, OhioAges 2–17 - NCT06311838Recruiting
Preventing opioid use among homeless youth
This study tests a program to help homeless youth build social connections and find stable housing to prevent opioid use. It will be conducted by Ohio State University.
Columbus, OhioAges 14–24 - NCT06290401Recruiting
Boosting self-management in teens with sickle cell disease
This study is testing a program to help adolescents with sickle cell disease better manage their health. It looks at how family, friends, and the clinic can support teens to take charge of their care.
Cincinnati, OhioAges 13–21
Where these studies are running in Ohio
Institutions with a site for the recruiting adolescent studies listed above.
- Cincinnati Children's Hospital Medical Center · 5 studies
- Nationwide Children's Hospital · 5 studies
- The Ohio State University · 4 studies
- Cleveland Clinic Foundation · 2 studies
- University of Cincinnati · 2 studies
- Apex Clinical Research Center
- Apex Clinical Research Center - Canton
- Centricity Research Columbus
What taking part in a adolescent study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Adolescent trials in other states
Common questions
- Are there adolescent clinical trials in Ohio?
- Yes. We're currently tracking 66 recruiting adolescent studies with a site in Ohio, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a adolescent study in Ohio?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Ohio to take part?
- Not necessarily. These studies have a site in Ohio, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a adolescent trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New adolescent studies open in Ohio regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.