Clinical trials
Adolescent clinical trials
Below are recruiting adolescent clinical trials, each written for real people, not researchers. We’re tracking 932 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03859297Recruiting
Testing how rumination changes in depressed teens
This study looks at what changes in “rumination” (repetitive worrying/thinking about negative thoughts) in teens with depression, and how those changes relate to recovery. It’s for ages 14–17 who have had major depression and meet specific screening and medical rules.
Columbus, OhioAges 14–17 - NCT06449014Recruiting
Mini-implant palate expander for teens and adults
This study tests whether a new type of palate expander that uses small implants (mini-screws) can safely widen the upper jaw in people 16 and older. It may be an option for you if your upper jaw is too narrow, even if you have already stopped growing.
Anderlecht, Brussels CapitalAges 16 years+ - NCT05667506RecruitingPhase 1/Phase 2
Check CNCT19 cell therapy for relapsed childhood ALL
This early-stage trial tests a personalized immune-cell treatment called CNCT19 in children and teens whose leukemia (ALL) has come back or not responded to prior therapy. It may help the immune system recognize and attack leukemia cells that carry CD19.
Hefei, AnhuiAges 3–18 - NCT06277063Recruiting
Nerve-stimulation device for headache in children and young adults
This trial tests if a gentle nerve-stimulating device worn on the neck (called nVNS) can prevent and treat common headaches like migraine, cluster, and tension-type headaches in children and young adults. If you often get headaches and want a drug-free option, this might help.
Guangzhou, GuangdongAges 7–20 - NCT06691698Recruiting
CO-OP therapy for teens with mild intellectual disability
This study tests a therapy called CO-OP, which helps teens with mild intellectual disability learn skills to reach their own goals. You'll work with a therapist once a week for 10 weeks, with a parent or adult to support you.
Kristianstad, Skåne CountyAges 13–17 - NCT06689085RecruitingPhase 3
Testosterone replacement study for adolescent boys with low testosterone
This trial tests a testosterone injection (XYOSTED) to see if it's safe and effective for replacing testosterone in teenage boys who have low levels due to a known medical condition. It lasts 52 weeks, with an optional 2-year follow-up.
Los Angeles, CaliforniaAges 12–17 - NCT06400810Recruiting
Teen Suicide Risk Study
This study looks at what leads teenagers to think about or attempt suicide. If your teen is 13–17 and is currently in the ER or psychiatric unit for suicidal thoughts or an attempt, they may be able to join.
Portland, OregonAges 13–17 - NCT06672939RecruitingPhase 3
Orforglipron for Weight Loss in Teens
This study tests a once-daily pill (orforglipron) to help adolescents with obesity or overweight plus related health problems lose weight. It offers a new option for teens who have struggled to lose weight with diet and exercise alone.
Oxnard, CaliforniaAges 12–17 - NCT06679881Enrolling by invitationPhase 3
Daily oral tablet to prevent hereditary angioedema attacks
This study tests a daily oral tablet called deucrictibant to see if it can prevent swelling attacks in people with hereditary angioedema (HAE). If you join, you will take the study drug for a longer period and track your symptoms in a diary.
Birmingham, AlabamaAges 12 years+ - NCT06670053Recruiting
Testosterone and brain development in teens
This study looks at how starting testosterone therapy affects brain development in transgender and gender-diverse youth. It may help you and your doctor understand the changes to expect.
Aurora, ColoradoAges 12–20 - NCT06670066Recruiting
Trial of let's talk birth control
This trial tests a program to help teens and young adults learn about birth control options during regular health visits. It may help you find the right method for your needs.
Sioux City, IowaAges 15–24 - NCT06679595Enrolling by invitation
Study of care coordination programs for children with chronic illness
This study looks at programs that help children with long-term health needs get better care from different doctors and hospitals. It aims to see how well these programs work and how to improve them.
BrusselsAges Any age - NCT06660199Recruiting
Text Support for Parents of Teens After a Suicidal Crisis
This study tests a text-message program to support parents of teens who come to the ER after suicidal thoughts or attempts. The goal is to see if the program helps parents and teens after they go home.
Ann Arbor, MichiganAges 13 years+ - NCT06390462Recruiting
Counseling for teens in school-based primary care
This study tests a brief counseling approach called Interpersonal Counseling for Adolescents (IPC-A) in school settings. It aims to help teens with emotional or social challenges before they become more serious, and it's designed for those who aren't already in mental health treatment.
HämeenlinnaAges 13–16 - NCT06651242Recruiting
Support for young cancer patients and their parents
This trial tests a decision-support program for children and teens with cancer and their parents. It aims to help families communicate and make choices together during treatment.
Kaohsiung CityAges 7–20 - NCT06655038Enrolling by invitation
Tobacco-free school policy improvement study
This study tests a new way to help schools better enforce their no-smoking rules. It looks at whether a special program can make these rules work better for students.
BrusselsAges 13–19 - NCT05304988Recruiting
Exercise therapy program for teens with cancer
This study is developing and testing (validating) an “exercise-focused” therapy for teenagers with cancer. It may help researchers see whether this approach is practical and beneficial, especially for teens’ communication and activity support.
Hong Kong, Hong Kong,ChinaAges 13–18 - NCT06638450Recruiting
Acupuncture for Teens with Stress and Insomnia
This study tests whether acupuncture can help teenagers who have been feeling anxious or down and having trouble sleeping. If you've had these feelings for more than 3 months and haven't taken medicine or had acupuncture recently, you may be able to join.
Hong Kong, Hong KongAges 15–22 - NCT06622681Recruiting
Adolescent health and development research study
This study follows teenagers to understand their health, growth, and well-being during adolescence. It may help develop better support for young people.
Singapore, SingaporeAges 13–15 - NCT06619171Enrolling by invitation
Teens with chronic pain: a study on distress
This study looks at why some teenagers with long-lasting chronic pain feel more distressed than others. It asks you to fill out a short survey on your phone every day for a period of time, to help researchers understand who is most at risk and when.
BathAges 12–19 - NCT06626425Recruiting
Well-being training for teens with depression
This study tests a 4-week well-being training program to see if it helps teens feel better and manage depression. You would use a smartphone app and answer surveys to track your mood and well-being.
Madison, WisconsinAges 14–19 - NCT06606002Recruiting
Group therapy for borderline symptoms in teens
This study tests if group schema therapy helps teenagers reduce borderline personality symptoms. It may be a good option if you have some borderline traits and can attend group sessions in Finnish.
Turku, Southwest FinlandAges 15–22 - NCT06616857Recruiting
Smartphone app to boost activity in teens with CF
This study tests a personalized smartphone app to help teens and young adults with cystic fibrosis be more active. The app provides tailored tips and support to encourage daily physical activity.
Jacksonville, FloridaAges 13–25 - NCT06607692RecruitingPhase 1/Phase 2
LuPARPed: Targeted radiation plus olaparib for certain childhood cancers
This trial tests a combination of a radioactive drug (Lutathera) and a targeted pill (olaparib) for children and teens whose solid tumors have come back or not responded to treatment and show high levels of a specific receptor (SSTR) on scans. The goal is to see if this two-drug approach can shrink tumors or stop them from growing.
Boadilla del Monte, MadridAges 3 years+
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Common questions
- Are there clinical trials for adolescent?
- Yes. Clin2 currently lists 932 recruiting adolescent studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a adolescent trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a adolescent trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.