Clinical trials
Advanced or Metastatic Breast Cancer clinical trials
Below are recruiting advanced or metastatic breast cancer clinical trials, each written for real people, not researchers. We’re tracking 6,186 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06780111RecruitingPhase 1/Phase 2
Combination therapy study for advanced esophageal cancer
This trial tests new drug combinations for people with advanced squamous cell cancer of the esophagus that hasn't been treated yet. It aims to see if these combinations can shrink tumors and help patients live longer.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT06709417RecruitingPhase 2
Immunotherapy plus chemo and radiation for advanced esophageal cancer
This trial is testing whether giving a combination of an immunotherapy drug (sintilimab) with chemotherapy, followed by radiation plus more chemotherapy (concurrent chemoradiotherapy), can help people with advanced esophageal cancer that cannot be removed surgically. The goal is to see if this approach shrinks the tumor and improves outcomes.
Shanghai, Shanghai MunicipalityAges 20–75 - NCT06712511Recruiting
Coffee's effect on energy and caffeine breakdown
This study looks at how coffee affects your body's energy use and how quickly you process caffeine. It may help explain why coffee affects people differently.
Shenzhen, GuangdongAges 18–40 - NCT06712667Recruiting
Coffee and intense exercise: a caffeine metabolism study
This study looks at how coffee affects people who do intense exercise, and how their bodies process caffeine. It may help understand if coffee can improve exercise performance or recovery.
Shenzhen, GuangdongAges 18–40 - NCT06714929Recruiting
School water study for students in grades K-5
This study looks at how a new water program in schools might affect student health and hydration. It includes watching what kids drink at lunch, checking teeth and body weight for older students, and asking 4th and 5th graders and staff about their drinks.
Henrico, VirginiaAges 4 years+ - NCT06717243Recruiting
Study on gene markers in lung cancer for treatment resistance
This study looks at genetic markers in two types of lung cancer (small cell and large cell neuroendocrine) to understand why some tumors stop responding to a standard treatment that combines chemotherapy with immunotherapy. If you have one of these cancers and are about to start this treatment, you may be able to join.
New York, New YorkAges 18–85 - NCT06722846Recruiting
Helping patients with advanced cancer plan care
This study looks at ways to help people with advanced cancer or aggressive lymphoma make better treatment decisions with their doctors. If you qualify, you'll be asked to read a short story about a patient in a similar situation and answer questions about your thoughts on care options.
Houston, TexasAges 18 years+ - NCT06725368RecruitingPhase 2
Chemo plus cetuximab after pembrolizumab for head and neck cancer
This trial tests a combination of two chemotherapy drugs (carboplatin and paclitaxel) plus a targeted therapy (cetuximab) for people with advanced head and neck cancer that has gotten worse after treatment with pembrolizumab (with or without initial chemotherapy). The goal is to see if this new combination can shrink tumors or slow the cancer's growth.
Ars-LaquenexyAges 18 years+ - NCT06726564RecruitingPhase 1
Study of MT027 for malignant pleural effusion
This trial tests a new drug called MT027 for people with advanced cancer that has spread to the lining around the lungs (pleura) and caused fluid buildup. The drug targets a marker on cancer cells called B7-H3. It may help control the fluid and the cancer.
BeijingAges 18 years+ - NCT06728410RecruitingPhase 2
Pemigatinib plus durvalumab for advanced bile duct cancer
This trial tests a combination of two drugs, pemigatinib and durvalumab, in people with a certain type of advanced bile duct cancer that has a specific genetic change (FGFR2 fusion or rearrangement). The goal is to see if this combination can help when standard treatments have stopped working.
Birmingham, AlabamaAges 18 years+ - NCT06730555Recruiting
HIV and hepatitis C testing for people who inject drugs
This study works with syringe service programs to see if offering opt-out HIV and hepatitis C testing helps more people get screened and connected to care. It focuses on programs that do not already offer this testing and are in high-need areas.
Miami, FloridaAges 18 years+ - NCT06731361Recruiting
Better prescribing for older nursing home residents
This study tests a better way for doctors to prescribe medicines for older nursing home residents. The goal is to make sure prescriptions are safer and more tailored to each person.
Apeldoorn, GelderlandAges 65 years+ - NCT06731452Recruiting
Brain health study with MRI and TMS
This study looks at brain activity patterns in healthy adults. You'll have an MRI and a non-invasive brain stimulation session (TMS) to help researchers understand how the brain works. If you're already in The BrainHealth Project, this is a chance to learn more about your own brain health.
Dallas, TexasAges 22–100 - NCT06732505RecruitingPhase 1
Ac-225 DOTATATE for SSTR+ GEP-NETs: A Safety Study
This trial tests a new drug, Ac-225 DOTATATE, in people with a type of gut or pancreas tumor (GEP-NET) that has specific proteins (SSTR) on its surface. The goal is to see if it is safe and helps shrink or slow the tumor.
Beijing, Beijing MunicipalityAges 18–80 - NCT06740487Recruiting
AR therapy for PTSD in military members
This study tests a new therapy using augmented reality (a type of headset that adds digital images to what you see) to help treat posttraumatic stress disorder (PTSD) in current or former military members. The therapy aims to make exposure therapy more effective by letting you face trauma-related situations in a controlled, virtual way.
Charleston, South CarolinaAges 18 years+ - NCT06744790Recruiting
Predicting breathing trouble after surgery with a new sensor
This trial tests a new sensor that monitors your breathing to predict if you might have trouble after surgery. It is for people who are staying overnight in the hospital and getting extra oxygen through a face mask.
Baltimore, MarylandAges 18 years+ - NCT06746194Recruiting
PET scan to check treatment response in advanced liver cancer
This trial uses a special PET scan (68Ga-FAPI) to see how well systemic therapy is working in people with advanced liver cancer that can't be removed by surgery. The goal is to find a better way to measure treatment effectiveness.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06757244RecruitingPhase 2
Dovipa: Immunotherapy and vitamin D with chemo for advanced pancreatic cancer
This trial tests whether combining the immunotherapy dostarlimab with vitamin D3 and standard chemotherapy (mFOLFIRINOX) can help people with stage IV pancreatic cancer. It aims to see if this new approach is safe and effective.
MarseilleAges 18–75 - NCT06760819RecruitingPhase 2
Sevacertinib for solid tumors with HER2 mutations
This study tests an oral tablet called sevacertinib in people with solid tumors (not lung cancer) that have a HER2 mutation. It aims to see how well the drug works and how safe it is for people who have tried other treatments or have no good options left.
Birmingham, AlabamaAges 18 years+ - NCT06769113RecruitingPhase 2
Study of HLX43 for advanced esophageal cancer
This trial tests a new drug, HLX43, for people with advanced esophageal squamous cell carcinoma that has stopped responding to or cannot tolerate standard treatments. It aims to see if HLX43 can help shrink or control the cancer.
Jinan, ShandongAges 18–75 - NCT06770010Recruiting
Digital brain training for kids with sickle cell disease
This trial is testing a digital program to help improve working memory (the ability to hold and use information in your mind) for children with sickle cell disease. If you join, you'll use a computer-based training program at home and researchers will see if it works and is easy to use.
Washington D.C., District of ColumbiaAges 7–16 - NCT06770075Recruiting
Brightline: testing a wellness app for college students
This study tests a smartphone app that may help students track and improve their mental well-being. Over 6 months, you will wear a device that monitors things like activity and sleep, and use a simple app to check in on your mood. It's designed for full-time undergraduates who do not have a current mental health condition and are not receiving mental health treatment.
SingaporeAges 18–25 - NCT06773611Recruiting
Heart failure and transplant registry study
This study is creating a registry to track and learn from people with advanced heart failure or who have had a heart transplant. By joining, you help researchers better understand these conditions and improve care.
BolognaAges 18 years+ - NCT06774989Recruiting
Drug level monitoring in metastatic melanoma treatment
This trial checks how much of two drugs, encorafenib and binimetinib, remain in your blood while treating advanced melanoma that cannot be removed by surgery. The goal is to learn if drug levels affect how well the treatment works.
Boulogne-BillancourtAges 18 years+
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Common questions
- Are there clinical trials for advanced or metastatic breast cancer?
- Yes. Clin2 currently lists 6,186 recruiting advanced or metastatic breast cancer studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a advanced or metastatic breast cancer trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a advanced or metastatic breast cancer trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.