Clinical trials
Advanced or Metastatic Breast Cancer clinical trials
Below are recruiting advanced or metastatic breast cancer clinical trials, each written for real people, not researchers. We’re tracking 6,204 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06100263Recruiting
Breast cancer resilience exercise program for Black women
This study tests a personalized exercise program designed to help Black women build strength and resilience after breast cancer treatment. It aims to see if guided exercise can improve physical and emotional well-being.
Ann Arbor, MichiganAges 18 years+ - NCT07009886Recruiting
Decision aid for advanced cancer patients considering more treatment
This study is testing a tool called TA-DA to help patients with advanced cancer and their caregivers make decisions about further treatment after at least two prior therapies. It aims to improve shared decision-making.
Houston, TexasAges 18 years+ - NCT04547907RecruitingPhase 3
Testing two HER2 breast cancer medicines before surgery
This trial compares two anti-HER2 medicines given before surgery to shrink HER2-positive early breast cancer. It aims to see which treatment works better as “neoadjuvant” therapy to improve outcomes while keeping you safe.
Zhengzhou, HenanAges 18–70 - NCT07692750RecruitingPhase 1/Phase 2
IBI343 plus chemo for advanced pancreatic cancer
This trial tests a new drug, IBI343, combined with chemotherapy for people with advanced pancreatic cancer that has gotten worse after first-line treatment. It looks at whether this combination can help shrink tumors or slow cancer growth.
Hangzhou, ZhejiangAges 18 years+ - NCT07415005RecruitingPhase 2
Lorlatinib and local therapy for ALK-positive lung cancer
This study combines a daily targeted pill (lorlatinib) with a short course of radiation or surgery to treat ALK-positive lung cancer. The goal is to see if this two-step approach delays the cancer from growing.
Houston, TexasAges 18 years+ - NCT05687851RecruitingPhase 2
Cadonilimab plus radiation for locally advanced cervical cancer
This trial studies whether adding cadonilimab (an immune therapy) to standard radiation can improve treatment for locally advanced cervical cancer. It may help your immune system work better against the cancer while radiation shrinks it.
Chongqing, CHNAges 18 years+ - NCT07286253RecruitingPhase 2
QL1706 plus chemo before surgery for advanced cervical cancer
This trial is testing whether adding the immunotherapy drug QL1706 to standard chemotherapy before surgery can improve outcomes for women with a certain type and stage of cervical cancer. It is for women whose cancer has not been treated yet and who are healthy enough for the treatment.
Guangzhou, GuangdongAges 18–70 - NCT07281001Recruiting
Trastuzumab deruxtecan study for breast cancer patients
This study looks at how well the drug trastuzumab deruxtecan works in women with breast cancer that has spread. It is for patients who have already taken this drug.
MoscowAges 18–80 - NCT04458532Recruiting
Exercise program to boost heart health after early breast cancer
This trial studies whether a structured exercise program can improve cardiovascular (heart and blood vessel) health in post-menopausal women after early-stage breast cancer treatment. It specifically targets women who have trouble with exercise and have completed cancer treatment within the last 1 to 5 years.
Hartford, ConnecticutAges 21–80 - NCT07269249Recruiting
Dostarlimab before surgery for advanced rectal cancer
This study looks at how well the immunotherapy drug dostarlimab works before surgery in patients with a specific type of advanced rectal cancer that has DNA repair problems (called dMMR/MSI-H). The goal is to see if it is safe and effective in the real world.
NaplesAges 18 years+ - NCT06516289RecruitingPhase 2
Neoadjuvant treatment for BRCA-mutated HER2-negative breast cancer
This trial tests a combination of two oral medications (HRS-1167 and famitinib) with or without an immunotherapy drug (camrelizumab) before surgery for women with a BRCA gene mutation and HER2-negative breast cancer. It aims to see if these drugs can shrink tumors before surgery.
Shanghai, Shanghai MunicipalityAges 18–70 - NCT07105033Recruiting
Focused ACT for advanced cancer patients
This study tests a counseling program called Focused ACT (FACT) to help patients with advanced cancer cope with stress and death anxiety. It involves talking with a counselor about important areas of your life.
Houston, TexasAges 18 years+ - NCT06860529RecruitingPhase 2
Immunotherapy plus chemo for early-stage HR+/HER2- breast cancer
This trial tests adding the immunotherapy drug serplulimab to standard chemotherapy for people with early-stage HR-positive, HER2-negative breast cancer. It aims to see if this combination can improve outcomes before surgery.
Zhengzhou, HenanAges 18 years+ - NCT06944587Recruiting
Personalized care for advanced pancreatic cancer
This trial is testing a new way to treat pancreatic cancer that has spread to nearby tissues but not to distant organs. It uses a tailored plan that may include chemotherapy and possibly surgery. The goal is to see if this personalized approach helps people live longer and better.
Bergen, NorwayAges 18 years+ - NCT06912152RecruitingPhase 1
Testing MT027 for advanced belly-lining cancers
This trial tests an experimental intraperitoneal therapy (MT027) for people whose advanced solid tumors have spread to the lining of the belly (peritoneum) and haven't responded to standard treatments. It aims to see if this new approach can help shrink or control the cancer.
Hangzhou, ZhejiangAges 18–70 - NCT07475182RecruitingEarly Phase 1
Cell therapy for advanced solid tumors with specific proteins
This trial tests a new type of cell therapy (CAR-T and targeted DC cells) for people with advanced solid tumors that have specific proteins. It aims to see if these immune cells can shrink tumors or slow their growth.
Haikou, HainanAges 18–75 - NCT06760364RecruitingPhase 1
CHT102 for Advanced Pancreatic Cancer with Mesothelin
This trial tests a new treatment called CHT102 for people with advanced pancreatic cancer that has a specific protein (mesothelin) on their tumor cells. It's for those who have already tried standard treatments without success or couldn't tolerate them.
TianjinAges 18–70 - NCT07224152RecruitingPhase 1/Phase 2
NBTXR3 plus radiation for inoperable lung cancer
This trial tests a new drug called NBTXR3, which makes cancer cells more sensitive to radiation. You'll get one injection of NBTXR3 into your lung tumor, followed by standard radiation. It is for people with early-stage non-small cell lung cancer who cannot have surgery.
Houston, TexasAges 18 years+ - NCT07040098RecruitingPhase 2
Optimizing immunotherapy with chemo-radiation for rectal cancer
This trial tests combining immunotherapy with standard chemotherapy and radiation before surgery for locally advanced rectal cancer. It aims to see if this approach can improve outcomes for patients whose tumors have certain genetic features (pMMR or MSS).
BeijingAges 18–75 - NCT07343024Recruiting
Finding a Personalized Drug for Advanced Cancer
This trial looks at whether drugs not usually used for your type of cancer can help you. It matches your tumor's test results to possible treatments and works with your doctor to try one.
Palo Alto, CaliforniaAges 18 years+ - NCT07246954Recruiting
Spiritual care help for advanced cancer patients
This study tests a program where a chaplain and doctor work together to support your spiritual beliefs about medical care. The goal is to see if it helps patients with advanced cancer feel more at peace with their treatment choices.
Houston, TexasAges 18 years+ - NCT07483983RecruitingPhase 2
Study of ASP3082 for advanced lung and pancreatic cancers with KRAS G12D mutation
This trial tests a new drug, ASP3082, for people with advanced non-small cell lung cancer or pancreatic cancer that has a specific gene change called KRAS G12D. The study will collect tumor and blood samples to understand how the cancer responds or becomes resistant to the treatment.
Villejuif, FranceAges 18 years+ - NCT06001749RecruitingPhase 2
Psilocybin for cancer pain study
This trial tests whether psilocybin (a psychedelic drug) can help with severe cancer pain. You may qualify if your pain is high despite strong medications and you are willing to be monitored closely.
Boston, MassachusettsAges 18 years+ - NCT07632365RecruitingPhase 1/Phase 2
Immunotherapy plus chemoradiation for inoperable stage III lung cancer
This trial tests a new combination of immunotherapy and chemotherapy before and after standard chemoradiation for patients with stage III lung cancer that cannot be surgically removed. The goal is to see if this approach improves outcomes compared to chemoradiation alone.
Shanghai, XuhuiAges 18 years+
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Common questions
- Are there clinical trials for advanced or metastatic breast cancer?
- Yes. Clin2 currently lists 6,204 recruiting advanced or metastatic breast cancer studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a advanced or metastatic breast cancer trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a advanced or metastatic breast cancer trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.