Clinical trials
Aged 65 Years or Older clinical trials
Below are recruiting aged 65 years or older clinical trials, each written for real people, not researchers. We’re tracking 1,066 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06090240Recruiting
Talking about future care plans after an ER visit
This study tests if talking with a counselor can help older adults and their family caregivers make plans for future medical care. It focuses on people who have recently visited the emergency room.
Hong KongAges Any age - NCT06052605Recruiting
Healthy aging study for older adults with epilepsy
This study looks at healthy aging in people with epilepsy. You will fill out a survey to help researchers understand your experiences and needs.
Cleveland, OhioAges 55–90 - NCT06052332Recruiting
Comparing two pre-surgery treatments for older adults with rectal cancer
This study compares two approaches to treating rectal cancer in people age 70 and older who have not yet had surgery. One approach gives chemotherapy and radiation before surgery, and the other adds more chemotherapy after radiation. The goal is to find which plan works better with fewer side effects.
Antwerp, AntwerpenAges 70 years+ - NCT05978336Recruiting
Physical activity help for older adults with walking difficulty
This study tests a program to help older adults who have some trouble walking become more active. If you are able to walk a short distance without major help and have no serious memory problems, you may be able to join and get support to move more safely.
Vancouver, British ColumbiaAges 70–89 - NCT05926219Recruiting
Study C-protein changes with fatigue and aging
This study looks at how a blood protein called C-protein relates to fatigue and aging, and how exercise affects it. You may be able to join if you’re otherwise healthy and willing to do muscle testing and activity monitoring.
Eugene, OregonAges 18–80 - NCT05824234Recruiting
REFOCUS program for mental health care teams
This trial tests whether a training program for mental health teams improves care for people with certain mental health conditions. You may be included if your clinic/team is using the REFOCUS training and you meet the study language and consent requirements.
Lyon, RhôneAges 15–65 - NCT05574634Recruiting
Study of brain signaling and distraction in aging adults
This study looks at how a deep brain area helps people focus and ignore distractions as we get older. You may be invited if you’re a healthy adult and can safely complete brain-related testing.
Blacksburg, VirginiaAges 18–75 - NCT05493241Recruiting
Behavior therapy to help older veterans stay independent
This study tests a behavior-change program (called Behavioral Activation) to help older veterans keep their independence and daily functioning. It may help if you’re at risk of getting weaker or less able to do everyday activities.
Bedford, MassachusettsAges 65 years+ - NCT05457725Recruiting
Study how aging affects learning to trust and distrust
This study looks at how thinking and learning processes change with age, especially around deciding what to trust. You may be asked to complete computer tasks and brief memory/thinking tests to understand these changes.
Gainesville, FloridaAges 18–100 - NCT05028309Recruiting
Study how obesity affects breathing and exercise in older adults
This study compares how body weight (higher or lower body fat) affects lung function, breathing during exercise, and exercise capacity in adults ages 65–75. You may be asked to do lung and exercise testing, but only if you meet health and activity restrictions.
Dallas, TexasAges 65–75 - NCT04339764RecruitingPhase 1/Phase 2
iPS cell eye transplant for dry macular degeneration
This early-phase study tests whether transplanting lab-made retinal cells from your own body can slow vision loss from geographic atrophy caused by dry age-related macular degeneration. It involves eye surgery and frequent follow-up to check safety and early signs of benefit.
Baltimore, MarylandAges 55–95 - NCT04284397RecruitingEarly Phase 1
Study of safe temperature conditions for adults
This early study looks at which hot or cold environments are safest and most challenging for adults who don’t have symptoms of disease. It may help improve safety guidelines so older adults can exercise or be exposed to temperature changes more safely.
University Park, PennsylvaniaAges 18 years+ - NCT03949647Recruiting
Study bone marrow samples from healthy adults every two years
This study collects bone marrow samples to look at healthy “bone marrow cells” and how they may change with aging. It may help researchers better understand aging biology by comparing samples over time.
Baltimore, MarylandAges 18–120 - NCT03370224Enrolling by invitation
Story memory training for older adults
This study tests a memory-skills training approach (the Modified Story Memory Technique) to help older adults with aging-related memory changes. You may be asked to do memory exercises, and some people may also complete an optional brain MRI scan.
East Hanover, New JerseyAges 65 years+ - NCT03178149RecruitingPhase 1
Study of a new eye treatment for dry macular degeneration
This Phase 1 trial tests the safety and side effects of ASP7317 in older adults whose central vision is worsening from dry age-related macular degeneration (geographic atrophy). If you qualify, you would receive treatment in the study eye and be closely monitored for about a year.
Phoenix, ArizonaAges 50 years+ - NCT07228624RecruitingPhase 2
Ruxolitinib before and after stem cell transplant for myelofibrosis
This study tests whether taking the drug ruxolitinib before, during, and after a stem cell transplant can improve outcomes for older patients with myelofibrosis or related bone marrow disorders. It aims to see if this approach can help the transplant work better and reduce side effects.
Seattle, WashingtonAges 18–75 - NCT06526260Recruiting
Very Brief Exposure for Social Anxiety in Teens and Young Adults
This study tests a very short, new type of exposure therapy for social anxiety in teens and young adults. Participants will also have a brain scan (MRI) to see how the therapy affects the brain.
Los Angeles, CaliforniaAges 16–22 - NCT06022965Recruiting
Telemedicine support for older adults with cancer
This study uses telemedicine (video or phone visits) to help older adults with cancer, especially those in underserved communities, get better care. If you're 65 or older and starting a new cancer treatment, you may be able to join from home in English, Spanish, or Chinese.
Duarte, CaliforniaAges 65 years+ - NCT07326592RecruitingPhase 4
Weekly treatment for emphysema caused by alpha-1 antitrypsin deficiency
This study tests a weekly injection of a protein replacement therapy for adults with emphysema due to alpha-1 antitrypsin deficiency. The goal is to see if this treatment can slow down the loss of lung density over three years.
AalborgAges 18–65 - NCT07437950RecruitingPhase 2
Comparing treatment lengths for venetoclax in older adults with newly diagnosed acute myeloid leukemia
This study tests whether a shorter or longer course of the drug venetoclax works better for older adults with a type of blood cancer called acute myeloid leukemia (AML) who are not healthy enough for intensive chemotherapy. The goal is to find the best treatment duration to control the cancer while reducing side effects.
Coeur d'Alene, IdahoAges 60 years+ - NCT04305834RecruitingPhase 2
Abemaciclib plus hormone pills for metastatic breast cancer in older adults
This Phase 2 study tests whether abemaciclib combined with standard hormone (endocrine) therapy can better control metastatic breast cancer in people age 70 and older. It may help if your cancer has already grown despite prior hormone therapy and/or other cancer medicines.
Duarte, CaliforniaAges 70 years+ - NCT07862933Recruiting
AI chat support for older adults with heart failure
This study tests an AI-powered chat system that offers social support to older adults with chronic heart failure. It may help you feel more supported and manage your condition better.
New Taipei City, New Taipei CityAges 60 years+ - NCT07876908Recruiting
Magnetic brain therapy for older adults with hard-to-treat depression
This trial tests a new intensive magnetic brain treatment (SAINT) for older adults whose depression has not improved with standard treatments. It aims to see if this treatment can also help with memory concerns, which are common in this group.
Costa Mesa, CaliforniaAges 65 years+ - NCT06284889Recruiting
Behavioral activation for depression in older adults
This study tests a program called Behavioral Activation, a type of talk therapy that helps you engage in positive activities to improve mood. If you are 65 or older and have mild to moderate depression, you may be able to join this telephone-based treatment.
Uppsala, UpplandAges 65 years+
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Common questions
- Are there clinical trials for aged 65 years or older?
- Yes. Clin2 currently lists 1,066 recruiting aged 65 years or older studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a aged 65 years or older trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a aged 65 years or older trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.