Clinical trials
Aggression clinical trials
Below are recruiting aggression clinical trials, each written for real people, not researchers. We’re tracking 90 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06609330Recruiting
Anger and aggression help after military betrayal
This study offers a program to help people who feel angry and have acted aggressively after a betrayal during military service. It aims to reduce anger and aggression so you can feel better and improve your relationships.
Fort Cavazos, TexasAges 18 years+ - NCT04793776Recruiting
MERA program to reduce aggression in PTSD
This trial tests a program called MERA to help people with PTSD-related symptoms manage emotions and reduce aggressive outbursts. It’s meant for Veterans who’ve had recent impulsive aggression and may benefit from structured skills practice and coaching.
Tampa, FloridaAges 18–64 - NCT05748808Recruiting
Biofeedback and virtual reality for controlling aggressive outbursts
This trial tests whether biofeedback plus virtual reality training can help people recognize emotions and gain better control over aggressive outbursts. It’s designed for people who have ADHD, Asperger syndrome, or oppositional defiant disorder (ODD) and still have frequent, hard-to-control aggression.
SevilleAges 10–16 - NCT06834373RecruitingPhase 2
Golcadomide and rituximab before CAR T for lymphoma
This trial tests a combination of two medications (golcadomide and rituximab) as a short-term treatment to shrink lymphoma before you receive CAR T-cell therapy. The goal is to make the CAR T treatment more effective for people whose lymphoma has come back or hasn't responded to previous treatments.
Scottsdale, ArizonaAges 18 years+ - NCT07776561Recruiting
Short-stay IV fluids to prevent pancreatitis after ERCP
This trial tests whether giving extra IV fluids before, during, and after an ERCP procedure can help prevent a common complication called post-ERCP pancreatitis (inflammation of the pancreas). If you are scheduled for an ERCP, you may be eligible to participate.
Westmead, New South WalesAges 18 years+ - NCT05293834Recruiting
Virtual reality training to reduce aggression
This trial tests a virtual reality (VR) program designed to help people in psychiatric care with aggression problems. If it works, it could help reduce aggressive behavior and improve coping skills in daily situations.
Basel, Canton of Basel-CityAges 12 years+ - NCT07344818RecruitingEarly Phase 1
CAR-T cell therapy targeting CD19 and CD20 for hard-to-treat B-cell lymphoma
This early-stage study tests a new type of immune cell therapy (CAR-T) that targets two proteins, CD19 and CD20, on your lymphoma cells. It is for people with aggressive B-cell lymphoma that has returned or not responded after several treatments. The goal is to see if this therapy can help shrink the cancer.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07218666RecruitingPhase 2
Zanzalintinib for aggressive prostate cancer
This trial tests a new drug, zanzalintinib, in men with a fast-growing type of prostate cancer that has spread and stopped responding to standard hormone therapies. It aims to see if the drug can help shrink tumors or slow the disease.
Milwaukee, WisconsinAges 18 years+ - NCT07212283Recruiting
Reducing aggression, promoting kindness to LGBTQ+ people
This trial tests a program designed to reduce aggressive behaviors and increase kindness towards people who are lesbian, gay, bisexual, transgender, or non-binary. It might help adolescents learn to treat others with more respect.
Bilbao, BIZKAIAAges 14–18 - NCT07191782Recruiting
Testing the PRAISE with Coaching Program in Schools
This study tests a program called PRAISE that helps teachers support students' social and emotional skills. It may help your child feel more connected and do better in school.
Philadelphia, PennsylvaniaAges 8 years+ - NCT06996132RecruitingPhase 2
Combination treatment for aggressive B-cell lymphoma that has returned
This trial tests a new combination approach for people whose aggressive B-cell lymphoma has come back or not responded to treatment. It uses a bispecific antibody (a type of drug that helps immune cells attack cancer cells) followed by CAR-T cell therapy (reprogramming your own immune cells to find and kill cancer), sometimes with a stem cell transplant.
TianjinAges 18–65 - NCT07484919Recruiting
VR therapy to reduce aggression in young offenders
This trial tests if a virtual reality intervention can help reduce aggressive behavior in young people aged 12-18 who are in a correctional facility. If you've had recent aggressive incidents, this study might offer a new way to manage anger.
Pozuelo de Alarcón, Cominity of MadridAges 12–18 - NCT07657494Recruiting
PET scan study for aggressive lymphoma patients
This study uses a special PET/CT scan to look at the environment around your lymphoma. The goal is to see if this scan can predict how well your treatment will work and your long-term outcome.
Beijing, Chao YangAges 18 years+ - NCT04948749Recruiting
Stenting plus medication to prevent stroke from narrowed brain arteries
This trial tests whether placing a stent in a severely narrowed brain artery, along with aggressive medication, can prevent another stroke better than medication alone. It is for people who had a mild stroke within the last 30 days due to a 70-99% blockage in a major brain artery.
Beijing, Beijing MunicipalityAges 18–85 - NCT05260957RecruitingPhase 2
CAR-T, mosunetuzumab, and polatuzumab for hard-to-treat lymphoma
This Phase 2 trial tests a combination approach to treat certain aggressive, relapsed, or refractory non-Hodgkin lymphomas. It may help by using CAR-T cells (a patient-specific immune treatment) along with other lymphoma medicines to shrink or control the cancer.
Miami, FloridaAges 18–80 - NCT05475925RecruitingPhase 1/Phase 2
Test drug DR-01 for specific blood cancer types
This early-phase study tests DR-01 to treat large granular lymphocytic leukemia (LGLL) or certain aggressive T-cell or cytotoxic lymphomas. It aims to see whether the drug is safe and can shrink or control the cancer.
Birmingham, AlabamaAges 18 years+ - NCT05863234RecruitingPhase 1/Phase 2
Safety study for aggressive NK-cell leukemia patients
This early-phase study tests a new treatment approach for people with aggressive NK-cell leukemia, focusing mainly on safety. It may be offered to patients whose disease matches the study’s specific leukemia diagnosis rules.
Hiroshima, HiroshimaAges 18–70 - NCT05978141Recruiting
T-cell lymphoma registry study
This study creates a registry for people with certain T-cell or NK-cell lymphomas. It collects health information and tumor samples to learn more about these diseases and improve future treatments.
Duarte, CaliforniaAges Any age - NCT06485076Recruiting
Early comfort care for multiple myeloma and aggressive lymphoma
This study offers a palliative care team (doctors and nurses focused on comfort and quality of life) to people newly diagnosed with multiple myeloma or with an aggressive lymphoma that has come back. The goal is to help manage symptoms early, so you feel better and stay stronger during your cancer treatment.
Toronto, OntarioAges 18 years+ - NCT06694740RecruitingPhase 2/Phase 3
Interferon gamma for immune recovery in the ICU
This trial tests if a drug called interferon gamma can help boost the immune system of patients in the ICU who are fighting serious infections. It is for adults who are on a breathing machine and have low immune function.
ParisAges 18 years+ - NCT06769282Recruiting
Preventing peer and dating violence for preteens in mental health programs
This study tests a program designed to teach preteens (ages 11–13) in intensive mental health treatment how to handle peer conflict and dating situations in a healthy way. It uses a trauma-informed approach to help build skills and reduce aggression.
Providence, Rhode IslandAges 11–13 - NCT06871488RecruitingPhase 4
ADHD irritability & aggression treatment with stimulants
This study tests whether CNS stimulant medications can improve irritability and aggression in children with ADHD. It looks for factors that predict who will benefit most.
Hershey, PennsylvaniaAges 7–12 - NCT07091279RecruitingPhase 2
Test of Propranolol for Severe Behaviors in Autism
This study tests a medication called propranolol to see if it can reduce aggression and other severe behaviors in adolescents and adults with autism. It might be an option if you have frequent and serious challenging behaviors that other treatments haven't helped.
Staten Island, New YorkAges 12–40 - NCT07091721Recruiting
Talking therapy for aggressive or violent young people
This trial tests a type of talking therapy called Mentalization Based Therapy for children and teens who show aggressive or violent behavior. It aims to help them understand their own and others' feelings, which may reduce outbursts and improve relationships.
Southampton, CalmoreAges 10–17
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Aggression trials by city
Studies with a site in or near these metro areas.
Aggression trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for aggression?
- Yes. Clin2 currently lists 90 recruiting aggression studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a aggression trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a aggression trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.