Clinical trials
Alcohol Use clinical trials
Below are recruiting alcohol use clinical trials, each written for real people, not researchers. We’re tracking 279 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05929677RecruitingEarly Phase 1
Study tests effects on impulsivity and how alcohol feels
This early-phase study looks at how alcohol affects impulsivity (tendency to act quickly) and people’s subjective experiences. You may be able to join if you drink regularly and meet the study safety rules.
Boston, MassachusettsAges 21–25 - NCT06618755Recruiting
Staying sober after detox: a coaching study
This study tests if motivational interviews after hospital detox help people with alcohol use disorder stay completely sober for one year. It might help you if you are committed to full abstinence and have a phone available.
MontpellierAges 18 years+ - NCT06787235Recruiting
Can a special diet help reduce alcohol intake?
This study tests whether a nutritional program (a modified ketogenic diet) can help people with alcohol use disorder reduce their drinking. It aims to find out if changing what you eat can support your goals around alcohol.
BernAges 18–80 - NCT06803706Recruiting
Gut bacteria changes during smoking quit attempt
This study looks at how quitting smoking changes your body's gut bacteria and metabolism. It is for people with a substance use disorder who want to stop smoking.
FehringAges 18 years+ - NCT05241990Recruiting
Help improve alcohol care for people with HIV in clinics
This study tries a practical clinic strategy to help HIV clinics better offer and carry out alcohol treatment. You may be able to join if you work at the clinic or if you have HIV and your alcohol use screening shows possible unhealthy drinking.
San Diego, CaliforniaAges 18 years+ - NCT02231840Recruiting
Study of how alcohol use changes over time
This study follows people over time to understand how alcohol use develops and changes. It may help researchers learn what factors are linked to changes in drinking, and it involves genetic testing and an MRI scan.
Bethesda, MarylandAges 18–100 - NCT04946851Enrolling by invitation
Alcohol use study for adults who join the NIAAA screening
This study uses a brain-and-behavior “assessment” (neuroclinical testing) to better understand addiction. You may be tested only if you are an adult and are enrolled in the NIAAA screening program, and you cannot join if you are acutely intoxicated.
Bethesda, MarylandAges 18–99 - NCT05548452RecruitingPhase 1/Phase 2
Microbiota transplant for advanced liver disease from alcohol
This trial tests whether giving a healthy mix of gut bacteria (an intestinal microbiota transplant) can improve outcomes in people with advanced liver disease caused by ongoing alcohol use. It may help rebalance the gut and support liver health, but participation depends on strict safety and diagnosis criteria.
Richmond, VirginiaAges 18 years+ - NCT06367348Recruiting
Couples program to cut alcohol use in Malawi
This study tests a program that helps couples in Malawi reduce alcohol use and strengthen their relationship. It is for people living with HIV who are in a long-term relationship and ready to work together with their partner.
ZombaAges 18 years+ - NCT06395467Recruiting
Integrated treatment for teens with substance use disorder
This trial tests a treatment program for teens and young adults with substance use disorders. It includes family members and is designed to support recovery and personal growth.
Farmington, ConnecticutAges 14–21 - NCT06486688Recruiting
Virtual program to help teens with substance use risk
This trial tests a virtual program integrated into pediatric check-ups to help teens at risk for alcohol or drug problems. It aims to identify teens who may need extra support and connect them with helpful resources.
Pleasanton, CaliforniaAges 12–17 - NCT06636227RecruitingPhase 1
Diclofenac dose study for alcohol use disorder
This study tests whether different doses of diclofenac, an anti-inflammatory drug, can help people reduce heavy drinking. It looks at how the drug affects drinking patterns and overall health.
Catonsville, MarylandAges 21–65 - NCT07056894Recruiting
Cognitive training for substance use in early psychosis
This study tests a computer-based cognitive training program to help people with early psychosis reduce their alcohol and cannabis use. The program is designed to improve thinking skills and may make it easier to cut back on substance use.
St. John's, Newfoundland and LabradorAges 16–30 - NCT07178990Recruiting
Wellness and recovery app for people on opioid treatment
This study tests if a smartphone app can help people taking medications for opioid use disorder and who also have alcohol use disorder. You will use the app for 6 months and provide feedback through surveys and saliva drug tests.
Ann Arbor, MichiganAges 19–63 - NCT04356274Enrolling by invitation
Improving access to addiction and mental health care at VA clinics
This study tests an approach to help VA clinics reach more Veterans with proven treatments for addiction and mental health conditions. It focuses on clinic-level processes (not individual medications) to increase how widely evidence-based care is delivered.
Palo Alto, CaliforniaAges 18 years+ - NCT06860607RecruitingPhase 1
Environment and Alcohol: A Pilot Study
A pilot study exploring the interaction between environment and alcohol consumption in individuals with alcohol use disorder (AUD), using smartphone-based ecological momentary assessment (EMA).
Baltimore, MarylandAges 21–100 - NCT06853873Enrolling by invitation
Alcohol counseling for safer pregnancies
This trial tests a counseling program to help pregnant women reduce risky alcohol use. The program is designed to support women in making healthier choices for themselves and their baby.
Cape TownAges 18 years+ - NCT05287711Recruiting
Motivational alcohol support to help prevent partner violence
This study tests an extra (adjunct) counseling approach to reduce harmful alcohol use in Veterans enrolled in the Strength at Home program. The goal is to help prevent intimate partner violence (IPV), especially when alcohol is involved.
Boston, MassachusettsAges 18 years+ - NCT05380765Recruiting
Help for First Nation teens to prevent substance use
This trial tests a positive, prevention-focused approach to help North American Indian (First Nation) teens make healthier choices about substance use. It involves both teens and an adult family member who supports good decision-making.
Kingston, Rhode IslandAges 10–14 - NCT06136195RecruitingPhase 1
Mavoglurant for alcohol craving in heavy drinkers
This trial tests whether a medication called mavoglurant can reduce alcohol cravings and drinking in people who are heavy drinkers with alcohol use disorder and are not looking for treatment.
New Haven, ConnecticutAges 21–50 - NCT07527871Enrolling by invitation
Emergency care screening and counseling for substance use prevention
This study tests whether screening patients in the emergency department for substance use, followed by a brief counseling session, can help prevent substance use problems and overdoses. You would be asked about your substance use and receive supportive counseling by phone or video.
Columbus, OhioAges 18 years+ - NCT04793685RecruitingPhase 2
Prazosin for alcohol withdrawal symptoms in alcohol use disorder
This study tests whether prazosin can reduce symptoms that happen when someone stops or cuts back on heavy drinking. It may help people with moderate-to-severe alcohol use disorder who also have alcohol withdrawal symptoms.
New Haven, ConnecticutAges 18–70 - NCT06104176Recruiting
Virtual reality therapy for alcohol use disorder
This study tests if virtual reality therapy can help people with alcohol use disorder stay abstinent. You must be sober for at least 15 days to participate.
Créteil, Île-de-France RegionAges 18–80 - NCT07095140Recruiting
Nicotine and flavor effects on alcohol use study
This study tests how different nicotine levels and flavors in oral nicotine products affect alcohol drinking in young adults who use nicotine daily. It could help understand how to reduce alcohol-related harm.
Columbus, OhioAges 21–30
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Common questions
- Are there clinical trials for alcohol use?
- Yes. Clin2 currently lists 279 recruiting alcohol use studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a alcohol use trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a alcohol use trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.