Clinical trials
Alcohol Use clinical trials
Below are recruiting alcohol use clinical trials, each written for real people, not researchers. We’re tracking 273 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06070649RecruitingPhase 1
DMT for Alcohol Use Disorder
This trial tests whether a single dose of DMT, a psychedelic, can help people with alcohol use disorder. It's a small early-phase study to see if the treatment is safe and promising.
New Haven, ConnecticutAges 21–65 - NCT05486234Recruiting
Study to reduce cannabis and alcohol use with teen and caregiver
This study looks at ways to help teens cut down on cannabis and alcohol use. You may qualify if you’ve been using both in the last three months and your caregiver is able to join and consent.
Charleston, South CarolinaAges 13–17 - NCT06584448Recruiting
Drinking, acetate, and stress study
This study looks at how acetate (a substance produced when the body breaks down alcohol) affects stress and drinking. It tests if giving acetate can help people with alcohol use disorder (AUD) reduce their drinking.
New Haven, ConnecticutAges 18–60 - NCT06259916Recruiting
EEG to tell alcohol vs. cannabis intoxication
This study uses electroencephalography (EEG) to see if brain activity can tell whether you are drunk, high, or both. Results might help improve safety in the future.
Fort Collins, ColoradoAges 21–50 - NCT06269627RecruitingPhase 4
Brain activity study for alcohol use treatment
This trial tests how the medication acamprosate affects brain activity in people with moderate to severe alcohol use disorder. It may help researchers understand how this treatment works.
Bethesda, MarylandAges 21–65 - NCT07216872Recruiting
Deep TMS to reduce heavy drinking in alcohol use disorder
This trial tests a non-invasive brain stimulation device (Deep TMS) to help people with alcohol use disorder reduce or stop heavy drinking. It uses magnetic pulses to target brain areas linked to addiction.
Tuscaloosa, AlabamaAges 18–86 - NCT04616781RecruitingPhase 2/Phase 3
Ketone drink study for alcohol use disorder brain function
This study tests whether a ketone-based treatment (a ketone ester) can change brain activity in people with alcohol use disorder who are not currently seeking treatment. You may also have brain scans, so the study is looking for safe MRI eligibility and certain health factors.
Philadelphia, PennsylvaniaAges 21–65 - NCT07692984Recruiting
Alcohol and drug use in people with schizophrenia or bipolar disorder
This study looks at how alcohol and substance use affects people with schizophrenia or bipolar disorder. It aims to understand if having these conditions together changes treatment or outcomes.
Bolu, BoluAges 18–65 - NCT04998916Recruiting
Brain stimulation to reduce heavy drinking in alcohol use disorder
This trial tests a type of noninvasive brain stimulation to see if it can reduce drinking and related “wanting” to drink. It may help people with alcohol use disorder who are currently drinking heavily.
Charleston, South CarolinaAges 21–65 - NCT05389930RecruitingPhase 2
Study how cannabis affects alcohol drinking
This Phase 2 study looks at whether using cannabis changes how much alcohol you drink. You may be able to take part if you’ve been drinking heavily and using cannabis recently and can meet health and screening requirements.
Providence, Rhode IslandAges 21–50 - NCT05534568Recruiting
Parent support program for families affected by pregnancy substance use
This program aims to help mothers and young children get safer, better support services when substance use occurred during pregnancy. It may help connect you (or your child) to the right community resources and reduce risk of ongoing alcohol or drug exposure.
Oklahoma City, OklahomaAges 18 years+ - NCT05677321Recruiting
Study how taste and smell differ in alcohol use disorder
This study compares how people with alcohol use disorder and people without it experience taste and smell. It also checks brain activity during taste/smell testing to understand individual differences that may be linked to alcohol use.
Bethesda, MarylandAges 18–65 - NCT05855668Recruiting
Study how brain and behavior differ in alcohol and cannabis use
This study looks at how people’s thoughts, brain-related measures, and behaviors differ between alcohol use disorder and cannabis use disorder. You may be asked to join group psychotherapy and complete assessments, which could help improve how care is planned for people like you.
Toronto, OntarioAges 18 years+ - NCT05995769RecruitingPhase 2
Psilocybin therapy with talk therapy for alcohol problems
This trial tests whether psilocybin (the active ingredient in magic mushrooms), given with talk therapy, can help people who want to reduce their heavy drinking. It is for people with at least moderate alcohol use disorder who are motivated to change.
Calgary, AlbertaAges 22–65 - NCT06030154Recruiting
Boosting positive feelings for people with alcohol use disorder
This study tests a program designed to help people with alcohol use disorder who also struggle with low mood or anxiety. It aims to increase positive emotions, which may make it easier to reduce drinking.
Tulsa, OklahomaAges 18–65 - NCT06105853Recruiting
Stress and brain activity in alcohol use disorder
This study looks at how people with alcohol use disorder respond to stress and what happens in the brain. You'll use a smartphone and may have an MRI scan to understand your stress responses.
Mannheim, Baden-WurttembergAges 18–65 - NCT06163651Recruiting
Parent-child support program for parents of young children
This trial tests a one-year program to help parents with young children. It offers support and resources to strengthen your family.
Enid, OklahomaAges 18 years+ - NCT06265506Recruiting
Virtual Reward Program for Cutting Back on Heavy Drinking
This study tests a virtual program that rewards you for reducing heavy drinking. You'd use a phone app, check in via Zoom, and get a glimpse into your drinking patterns through a blood test. It might be a good fit if you want to cut back on heavy drinking without going to an in-person clinic.
Spokane, WashingtonAges 18 years+ - NCT06318026Recruiting
Personalized alcohol care for primary care patients
This study tests a new way to help people who drink heavily get personalized support for cutting back or quitting. You may qualify if you have had a recent primary care visit and screening shows risky drinking.
Seattle, WashingtonAges 18 years+ - NCT06405607RecruitingPhase 2
Psilocybin vs Ketamine for Alcohol Use Disorder Trial
This trial tests two psychedelic-assisted therapies, psilocybin and ketamine, to see which works better for reducing heavy drinking in people with alcohol use disorder (AUD). You'll receive either drug along with counseling, and the study monitors safety closely.
Iowa City, IowaAges 21–65 - NCT06415721Recruiting
TMS guided by brain scans for alcohol use disorder
This study uses a brain stimulation technique called TMS combined with MRI scans to treat alcohol use disorder. It aims to see if targeting specific brain connections can help reduce drinking.
Palo Alto, CaliforniaAges 25–75 - NCT06493773Recruiting
Alcohol help for new liver disease diagnosis
This trial tests a program to help people recently diagnosed with alcohol-related liver disease cut back on drinking. If you qualify, you may get support to improve your liver health.
Køge, KøgeAges 18 years+ - NCT06559995RecruitingPhase 2/Phase 3
Ketone drink for alcohol withdrawal
This study tests whether a special ketone drink can ease alcohol withdrawal and help your brain heal. If you have been drinking heavily for at least 3 years and are having withdrawal symptoms now, this might be an option for you.
Philadelphia, PennsylvaniaAges 18–65 - NCT06593652Recruiting
How caregivers can help teens with alcohol use
This study looks at how involving caregivers in a brief talk with a primary care provider might help teens who are drinking alcohol or using other substances. It aims to find better ways to support teens and their families.
Indianapolis, IndianaAges 12–17
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Alcohol Use trials by city
Studies with a site in or near these metro areas.
Alcohol Use trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for alcohol use?
- Yes. Clin2 currently lists 273 recruiting alcohol use studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a alcohol use trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a alcohol use trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.