Clinical trials · Massachusetts
Allergy clinical trials in Massachusetts
We’re tracking 30 recruiting allergy studies with a site in Massachusetts — including Early Phase 1, Phase 1, Phase 1/Phase 2, Phase 2 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies in Massachusetts
- NCT07768371RecruitingPhase 3
Remibrutinib for peanut, milk, or egg allergies
This study tests an investigational drug called remibrutinib to see if it can reduce allergic reactions to peanuts, milk, or eggs. It is for people aged 12 to 65 who have been diagnosed with a food allergy and are willing to participate in food challenges.
Boston, MassachusettsAges 12–65 - NCT05695261RecruitingPhase 2
Oral microbiome capsules for peanut allergy in teens
This Phase 2 study tests whether taking capsules made from donor gut microbes is safe and can reduce allergic reactions to peanuts. It involves peanut allergy testing and close follow-up with stool samples and check-ins.
Boston, MassachusettsAges 12–17 - NCT06406114RecruitingPhase 2
Better Allergy Testing for Cephalosporin Antibiotics
This study tests better ways to diagnose allergies to common cephalosporin antibiotics, like Keflex and Rocephin. By participating, you may learn if you are truly allergic to these medicines and if they are safe for you to take in the future.
Boston, MassachusettsAges 18–70 - NCT03936998RecruitingPhase 1/Phase 2
Study drug for peanut allergy to change immune response
This early-phase study tests VE416, a treatment meant to help reduce peanut allergy reactions by changing how the immune system responds. If you have documented peanut allergy, you may receive the study medicine and, for some people, take part in a supervised peanut “entry challenge.”
Boston, MassachusettsAges 12–55 - NCT07447869RecruitingEarly Phase 1
Lymph Node Exam in Cat Allergy Treatment Study
This study looks at lymph nodes in the neck to understand how the body responds to cat allergy treatments. It may help researchers improve allergy shots or other therapies for people with cat allergies.
Boston, MassachusettsAges 18–45 - NCT07279467Recruiting
Peanut allergy food challenge biomarker study
This study aims to identify markers in the blood that could help predict how severe a peanut allergy reaction might be. If you qualify, your child will undergo a supervised peanut challenge to see how their body responds.
Boston, MassachusettsAges 1–17 - NCT07287033RecruitingPhase 1
Safety study of MY006 in healthy people and people with peanut allergy
This early-phase study tests a new investigational medication (MY006) to see if it is safe and how the body processes it. It is given to both healthy volunteers and people with peanut allergy. The goal is to gather safety information before larger trials.
Boston, MassachusettsAges 12–55 - NCT07220811RecruitingPhase 2
Testing a new drug for food allergies
This trial tests a new medication called RPT904 in people with IgE-mediated food allergies to foods like peanut, milk, egg, cashew, or walnut. The goal is to see if it reduces allergic reactions when you eat a small amount of the food.
Boston, MassachusettsAges 12–55 - NCT07015996RecruitingPhase 2
Tezepelumab for peanut allergy oral immunotherapy
This trial tests whether adding tezepelumab (a biologic drug) to peanut oral immunotherapy can help people with peanut allergy better tolerate small amounts of peanut protein without having an allergic reaction.
Boston, MassachusettsAges 12–55 - NCT06943534RecruitingPhase 2
Omalizumab for severe food allergies: weight-based dosing study
This trial tests if omalizumab (a drug that blocks allergy reactions) can help people with multiple food allergies. You might qualify if you have severe allergies to at least two foods like peanut, tree nuts, egg, or milk.
Boston, MassachusettsAges 1–55 - NCT07757802RecruitingPhase 1
HIV vaccine nanoparticle and mRNA booster for healthy adults
This study tests a new HIV vaccine that uses tiny particles (nanoparticles) and an mRNA booster — similar to some COVID vaccines. The goal is to see if it is safe and helps your body fight HIV. It's for healthy adults who do not have HIV.
Boston, MassachusettsAges 18–55 - NCT07675811RecruitingPhase 3
Study of a new treatment for cat allergy related eye symptoms
This trial tests an injectable treatment that may help manage eye allergy symptoms caused by cat allergies. It aims to see if the treatment is safe and effective for adults and children, and includes a controlled cat exposure challenge.
Andover, MassachusettsAges 8 years+ - NCT07569029RecruitingPhase 1
HIV vaccine with treatment break to boost immune response
This Phase 1 trial tests two new HIV vaccines (DV700P-RNA and DV701B1.1-RNA) combined with a monitored break from HIV medications in people with well-controlled HIV. The goal is to see if this approach safely strengthens the immune system's ability to fight HIV.
Boston, MassachusettsAges 18–60 - NCT07536308RecruitingPhase 1
Nasal COVID-19 booster vaccine safety trial
This trial tests a new nasal spray COVID-19 booster vaccine. It aims to see if the vaccine is safe and produces a strong immune response when given through the nose and inhaled, in people who have already been vaccinated.
Boston, MassachusettsAges 18–64 - NCT07390474RecruitingPhase 1
HIV vaccine safety and immune response study for healthy adults
This study tests two experimental mRNA-based HIV vaccines to see if they are safe and create an immune response. It is for healthy adults aged 18 to 55 who do not have HIV.
Boston, MassachusettsAges 18–55 - NCT07390955RecruitingPhase 1
Safety study of three anti-HIV antibodies in healthy adults
This study is testing three experimental antibodies (ePGT121v1-LS, PGDM1400LS, and VRC07-523LS) that may help prevent HIV. It’s looking at their safety and how long they stay in the body. Healthy volunteers without HIV can join.
Boston, MassachusettsAges 18–55 - NCT07108387RecruitingPhase 2
Stopping or reducing tocilizumab for well-controlled giant cell arteritis
This study compares stopping tocilizumab (Actemra) completely versus reducing the dose in people whose giant cell arteritis has been well controlled for at least a year. The goal is to find out which approach keeps the disease in remission while reducing medication side effects.
Boston, MassachusettsAges 50 years+ - NCT06970977Recruiting
Chronic sinusitis questionnaire validation study
This study is testing a new questionnaire to better understand chronic sinusitis symptoms. It may help improve how doctors diagnose and treat the condition.
Boston, MassachusettsAges 18 years+ - NCT06796686RecruitingPhase 1
HIV vaccine safety and immune response study for healthy adults
This trial tests a new two-part HIV vaccine regimen in healthy adults without HIV. The goal is to see if it is safe and produces an immune response that could help prevent HIV.
Boston, MassachusettsAges 18–55 - NCT06665646RecruitingPhase 1
HIV vaccine booster study for previous trial participants
This study tests a booster vaccine for HIV in people who were part of an earlier HIV vaccine trial. The goal is to see if it's safe and helps the immune system fight HIV better.
Boston, MassachusettsAges 18–60 - NCT06136091Recruiting
Asthma study in select communities using a smartphone app
This study looks at how asthma affects people in certain communities and tests a new way to manage it using a smartphone app. It is for people with long-standing asthma and those without asthma, to compare their health over time.
Boston, MassachusettsAges 6–17 - NCT06033196RecruitingPhase 2
Tocilizumab after lung transplant
This study tests whether the drug tocilizumab can help prevent your body from rejecting a new lung after transplant. It might help improve the success of your transplant by reducing immune system activity.
Boston, MassachusettsAges 12–75 - NCT06055608RecruitingPhase 2
Improving kidney transplant outcomes in teens and young adults
This trial tests a new approach to help teenagers and young adults keep their first kidney transplant working well. It looks at how to improve long-term success by carefully managing the immune system around the time of transplant.
Boston, MassachusettsAges 13–20 - NCT06056102RecruitingPhase 1
CAR-T cell therapy to help highly sensitized kidney transplant patients
This trial tests whether a special immune cell treatment (CAR-T cells) can lower the antibodies that make it very hard for you to receive a kidney transplant. If it works, you might become eligible for a transplant sooner.
Boston, MassachusettsAges 18–65
Allergy trials by city in Massachusetts
Where these studies are running in Massachusetts
Institutions with a site for the recruiting allergy studies listed above.
- Massachusetts General Hospital · 7 studies
- Boston Children's Hospital · 2 studies
- Brigham and Women's Hospital · 2 studies
- Brigham and Women's Hospital Vaccine CRS (BWH VCRS) · 2 studies
- Andover Eye Associates
- Beth Israel Deaconess Medical Center / BIDMC VCRS (Site ID: 32077)
- Beth Israel Deaconess Medical Center VCRS (BIDMC VCRS Site # 32077)
- Boston Children's Hospital (Site #: 71001)
What taking part in a allergy study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Allergy trials in other states
Common questions
- Are there allergy clinical trials in Massachusetts?
- Yes. We're currently tracking 30 recruiting allergy studies with a site in Massachusetts, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a allergy study in Massachusetts?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Massachusetts to take part?
- Not necessarily. These studies have a site in Massachusetts, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a allergy trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New allergy studies open in Massachusetts regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.