Clinical trials
Alzheimer clinical trials
Below are recruiting alzheimer clinical trials, each written for real people, not researchers. We’re tracking 623 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05374278RecruitingPhase 1/Phase 2
PET scan test for a dementia brain tracer
This early-phase study tests a new PET scan tracer that targets a brain chemical transport system involved in dementia. It aims to see if the tracer can safely and clearly show brain changes, which could help future dementia diagnosis or tracking.
San Francisco, CaliforniaAges 40–75 - NCT05395624RecruitingPhase 1/Phase 2
Safety imaging study of a PET tracer in ALS, Alzheimer, MS, Parkinson
This early-phase study tests the safety of a radioactive tracer (“18F-OP-801”) and how the tracer moves through the body (biodistribution) in people with ALS, Alzheimer’s disease, multiple sclerosis, Parkinson’s disease, and in healthy volunteers. It also measures how the body processes the tracer (“pharmacokinetics”) to support future studies.
San Francisco, CaliforniaAges 18–80 - NCT05452031Recruiting
Sleep program for people with dementia and their caregiver
This study tests a “dyadic” sleep health approach, meaning it works with both you and your caregiver together. It aims to improve sleep when dementia is causing frequent sleep problems, and to see whether a caregiver-involved plan helps both of you.
La Jolla, CaliforniaAges 18 years+ - NCT05460143Recruiting
Optical brain scanning to study memory and thinking
This study uses brain “optical” and possibly MRI scans to understand how thinking and memory work in people with Lewy body dementia, Alzheimer’s disease, or mild memory problems. It may help researchers find better ways to measure brain changes and cognition over time.
CambridgeAges 18 years+ - NCT05468905Recruiting
Study of aging and early thinking changes over time
This study follows adults 40+ to better understand and track changes in memory and thinking as people age. It groups people with normal thinking, subjective complaints, mild cognitive impairment, early Alzheimer’s, and vascular (blood vessel) related brain changes to find what predicts progression.
Hangzhou, ZhejiangAges 40–99 - NCT05534607Recruiting
Community hula program for dementia risk in older Native Hawaiians
This study tests whether joining a community hula (dance) program can help people reduce future dementia risk. It focuses on older Native Hawaiian or Pacific Islander adults who already have mild memory concerns and certain health conditions like high blood pressure or diabetes.
Honolulu, HawaiiAges 50–75 - NCT05558709Recruiting
Test for thinking and behavior skills in neurodegenerative disease
This trial checks a new kind of paper-and-pen (or computer-based) test to better measure thinking and social/behavior skills in people with certain brain diseases. It may help researchers improve how these skills are tracked and understood over time.
ParisAges 18–90 - NCT05561205Recruiting
Brain stimulation to treat persistent apathy
This trial tests a noninvasive brain stimulation treatment (called rTMS) to help people who have had ongoing apathy (lack of motivation/interest) for at least a month. You might benefit if your apathy is persistent, your other symptoms are stable, and you meet the safety and medication rules.
Toronto, OntarioAges Any age - NCT05565833RecruitingPhase 2
Online sleep program for insomnia and thinking problems
This Phase 2 study tests an internet-based sleep program to help older adults with insomnia and related thinking difficulties. It may help improve sleep and reduce how much tiredness and sleep disruption affect daily life.
Charlottesville, VirginiaAges 65 years+ - NCT05574634Recruiting
Study of brain signaling and distraction in aging adults
This study looks at how a deep brain area helps people focus and ignore distractions as we get older. You may be invited if you’re a healthy adult and can safely complete brain-related testing.
Blacksburg, VirginiaAges 18–75 - NCT05591027RecruitingPhase 1
Testing Centella asiatica for memory problems in older adults
This Phase 1 study tests whether Centella asiatica (a plant-based supplement) is safe and reaches its intended target in people with mild cognitive impairment or early Alzheimer’s disease. It also checks how it affects memory-related brain measures like MRI scans, which is why multiple scans are required.
Portland, OregonAges 60–85 - NCT05592366Recruiting
Testing a hospital tool for unpaid dementia caregivers
This study is testing a care-partner support tool for people who provide unpaid care to a hospitalized adult loved one or partner with dementia-related needs. It may help caregivers and hospitals communicate and coordinate better during a hospital stay.
Madison, WisconsinAges 18 years+ - NCT05592678Recruiting
Study brain and memory test changes in Alzheimer’s or mild issues
This study looks at how well people with Alzheimer’s disease (AD) or mild cognitive impairment (MCI) perform on standardized memory/brain tests. It may help researchers understand changes over time, and whether certain types of brain signals or test results track with the condition.
San Antonio, TexasAges 65–100 - NCT05597124RecruitingPhase 2
Exercise program to improve brain health in older Black adults
This Phase 2 study tests whether a structured exercise program can improve brain health in adults age 60 and older who are less active and have early thinking/memory concerns. It may help maintain or improve thinking abilities over time, with medical supervision throughout the study.
Newark, New JerseyAges 60 years+ - NCT05606341RecruitingPhase 1
Testing a diabetes-style shot to boost brain immunity in early Alzheimer’s
This Phase 1 study tests whether stimulating the immune system (through a receptor called TLR9) is safe and may affect brain changes in people with early Alzheimer’s. It mainly enrolls older adults with memory impairment confirmed by specific amyloid imaging.
New York, New YorkAges 60–85 - NCT05623124Recruiting
Alzheimer’s and dementia brain and memory study with caregiver support
This is a study that enrolls people with mild Alzheimer’s-related memory problems or dementia to help build a research “neurobank.” It also involves memory testing and may include brain scans, with a stable caregiver to support follow-up.
Shanghai, Shanghai MunicipalityAges 50–90 - NCT05629871Recruiting
Tracking sleep changes in early Alzheimer’s and thinking decline
This study looks at how sleep and wake patterns change in people with early Alzheimer’s, and whether these changes relate to memory and thinking decline. You may be asked to do questionnaires, sleep diaries, and possibly a diagnostic spinal fluid test (lumbar puncture) to measure biomarkers.
MontpellierAges 50–85 - NCT05641688RecruitingPhase 3
PET brain scan study for people with terminal illness
This Phase 3 study tests an amyloid/tau PET brain imaging agent (called [18F]PI-2620). It aims to see how well the scan helps with brain pathology findings in people who are expected to have a life expectancy of 1 year or less.
Phoenix, ArizonaAges 50 years+ - NCT05649514Recruiting
Studying sleep problems in early Alzheimer’s risk patients
This study looks at sleep problems in people with mild Alzheimer’s disease and whether sleep measurements and questionnaires can help researchers understand early changes. You may be able to join if your diagnosis is mild and you can complete repeated sleep and thinking questionnaires with a family caregiver’s help.
Montpellier, HéraultAges 50–85 - NCT05658913Recruiting
Tau PET/CT scan study for people in an ongoing cohort
This study uses a special brain scan (tau PET/CT) to look for a protein called tau, and it ties the scan results to information collected in an existing research program. It may help researchers better understand brain changes over time.
Boston, MassachusettsAges 18–120 - NCT05661084Recruiting
Non-surgery brain stimulation for dementia thinking and movement
This study tests whether a non-invasive brain stimulation device (tES) can improve thinking and movement problems in people with dementia. You (and your caregiver, if needed) will be asked to follow the study plan and attend visits so researchers can measure results and safety.
Boston, MassachusettsAges 55 years+ - NCT05710549Recruiting
Brain study of autobiographical memory using brain stimulation
This study looks at how the brain supports remembering your own past experiences. It tests brain mechanisms using brain scanning (MRI) and noninvasive brain stimulation to see how these memory processes work.
Geneva, Canton of GenevaAges 18–85 - NCT05741853Recruiting
Speech therapy study for bilingual people with primary progressive aphasia
This study looks at how well speech-language therapy works in bilingual people with primary progressive aphasia, a condition that gradually affects language. It also tests whether different language skills (Spanish/Catalan or Spanish/English) affect response to treatment.
Austin, TexasAges 40 years+ - NCT05785156Recruiting
Quick test study to predict stroke and memory disease outlook
This study tests quick new methods to measure “slowed actions” in people with stroke or memory-related brain conditions. The goal is to see whether these quick tests can help predict future outcomes and guide care.
AmiensAges 40–85
Hear when a new Alzheimer trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for alzheimer?
- Yes. Clin2 currently lists 623 recruiting alzheimer studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a alzheimer trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a alzheimer trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.