Clinical trials
Antibiotics clinical trials
Below are recruiting antibiotics clinical trials, each written for real people, not researchers. We’re tracking 296 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05777603RecruitingPhase 1
Aerosol antibiotics plus pembrolizumab for advanced lung cancer
This trial studies whether inhaled (aerosol) antibiotics combined with pembrolizumab can help people with advanced non-small cell lung cancer that has grown despite standard first treatment. It aims to improve cancer control by testing this new combination in Phase 1 safety and early effectiveness.
Bethesda, MarylandAges 18–120 - NCT05319067Recruiting
Gut bacteria study in toddlers on long-term reflux antibiotics
This study compares gut bacteria (microbiome) in toddlers who take an antibiotic to prevent urine infections for vesicoureteral reflux, versus other similar children. It may help researchers understand how long-term antibiotic use and reflux affect gut health and future risk.
MontpellierAges 1–3 - NCT05571722RecruitingPhase 4
Antibiotic prevention for surgical site infections
This trial tests whether using linezolid or vancomycin before surgery can better prevent infections at the surgical wound in people at higher risk. You might be considered because you either can’t take certain standard antibiotics (beta-lactams) and/or may carry MRSA bacteria.
MarseilleAges 18 years+ - NCT05248620Recruiting
Antibiotics to prevent infections in hemodialysis catheters
This trial tests whether taking preventive antibiotics (or a placebo sugar pill) can lower the risk of infections in people who receive hemodialysis through a catheter. It may help protect you from serious catheter-related infections, but you must be able to follow the study’s medicine and consent rules.
Copenhagen, Capital RegionAges 18 years+ - NCT04678154RecruitingPhase 3
Antibiotic trial for severe open fractures of the leg or foot
This trial tests a new way of giving antibiotics to people with severe open fractures in the leg, ankle, or foot. The goal is to see if it helps prevent infections after surgery.
Redwood City, CaliforniaAges 18–64 - NCT04444440RecruitingPhase 4
Antibiotic prevention after bladder Botox for overactive bladder
This trial studies whether taking an antibiotic around the time of bladder Botox can lower the risk of urinary infections. It’s for women with overactive bladder who tried standard medicines but didn’t get enough relief.
Edmonton, AlbertaAges 18 years+ - NCT03636464Recruiting
Antibiotic testing in people on kidney dialysis
This trial studies how common antibiotics move through the body when someone is on kidney replacement therapy (dialysis), including when dialysis starts during treatment. The results may help doctors choose the right antibiotic dose and timing for better infection treatment.
Abu DhabiAges 18 years+ - NCT06020716RecruitingPhase 4
Antibiotics for chronic wet cough in toddlers
This study tests whether the antibiotic Augmentin helps children aged 9 months to 3 years with long-lasting wet cough (more than 4 weeks). It aims to find better ways to treat and understand this common problem in toddlers.
ÅlesundAges 9 months–3 years - NCT02652169Recruiting
Antibiotic or antiseptic treatment for chronic leg ulcers
This study tests a wound treatment using topical antibiotics or antiseptics to help chronic (long-lasting) leg ulcers heal and control local infection. It may help people whose ulcers are not responding well to standard care.
ViennaAges 18 years+ - NCT03713528Enrolling by invitationPhase 4
Antibiotic placed in bone to help save an infected knee implant
This trial tests whether putting antibiotics directly inside the bone during surgery can improve outcomes for an infected knee prosthesis when the implant is being kept. It may help more people avoid needing full implant removal and replacement.
San Francisco, CaliforniaAges 18 years+ - NCT04460313Recruiting
Testing bacteria in children’s noses and ears
This study looks at bacteria (especially pneumococcus) in the nose and throat of children. It includes children with ear infections or healthy children, to understand which germs are carried and how they relate to illness.
CréteilAges 6 months–15 years - NCT06148025RecruitingPhase 4
Do antibiotics affect vaccine responses?
This study looks at whether taking a short course of antibiotics can change how your body responds to two vaccines (BCG and yellow fever). It may help researchers find ways to make vaccines work better.
Adelaide, South AustraliaAges 18–35 - NCT06258551Recruiting
Tracking hard-to-treat bacteria in ICU and transplant patients
This study will track how certain hard-to-treat bacteria spread and cause infections in people who are in the intensive care unit (ICU) or have had a stem cell transplant. The goal is to better understand and prevent these infections in vulnerable patients.
Houston, TexasAges 18 years+ - NCT07492134RecruitingPhase 2
Antibiotics vs placebo for mild diverticulitis
This study tests whether antibiotics are necessary for mild diverticulitis or if a placebo works just as well. Participants are treated in the emergency department and followed using a smartphone app.
Nashville, TennesseeAges 18–90 - NCT07599865RecruitingPhase 2
Bubble study for knee infection after joint replacement
This trial tests if a contrast agent used in ultrasound can help surgeons see pockets of infection around knee implants during revision surgery. It may help doctors do a better job cleaning out the infection.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07237971Recruiting
Making medicine use better in Elche
This study works with the community to find ways to use medications like antidepressants, blood pressure drugs, and antibiotics more wisely. It is a collaboration among residents, healthcare workers, and local groups to create solutions together.
Elche, AlicanteAges 18 years+ - NCT05469984Recruiting
Two antibiotic plans for water breaking before labor
This trial compares two different “preventive” antibiotic schedules for pregnant people whose water breaks more than 18 hours before labor, or who go into preterm labor. The goal is to see which plan better helps mother and baby by reducing infection-related complications.
NahariyaAges 18–48 - NCT06327113RecruitingPhase 2
Antibiotic wound spray for hard-to-heal chronic wounds
This study tests a wound spray containing antibiotics to treat chronic wounds that haven't healed with standard care. It might help if you have a wound on your leg, arm, or trunk that has been present for over 4 weeks and is not getting smaller.
Los Angeles, CaliforniaAges 18 years+ - NCT05361941Recruiting
Antibiotic graft to help bone regrow in infected knee surgery areas
This trial tests an antibiotic “graft” placed into or near infected bone cavities around a knee replacement (TKA) to help new bone grow. You may be considered if you have an infected knee implant area and can safely take part in follow-up visits and treatment.
Los Angeles, CaliforniaAges 22 years+ - NCT07545876Recruiting
Understanding pneumococcal bacteria in Malaysian children
This study collects nasal swabs from young children in Malaysia to learn which types of pneumococcal bacteria are present, which antibiotics work against them, and how they spread. This information helps doctors better treat and prevent pneumococcal infections in children.
Kuala Lumpur, Kuala LumpurAges birth–5 years - NCT06387147RecruitingPhase 3
Oral antibiotics for acute mesenteric ischemia
This trial tests whether taking oral antibiotics (gentamicin and metronidazole) can treat acute mesenteric ischemia caused by an artery blockage, instead of using IV antibiotics. It's for people who don't need emergency surgery and don't have a serious infection.
Clichy, FranceAges 18–90 - NCT06410443Recruiting
Steroid treatment for radiation-induced bowel injury
This trial tests if local steroids can help heal bowel damage caused by radiation therapy for cancer. It may reduce pain, bleeding, and urgency, and improve quality of life.
Shenyang, LiaoningAges 18 years+ - NCT07451171RecruitingPhase 2
Comparing antibiotics for gut bacteria in children
This study compares three different antibiotics to treat small intestine bacterial overgrowth (an overgrowth of bacteria in the gut) in children in Bangladesh. It aims to find which antibiotic works best.
DhakaAges 1–2 - NCT06605820Recruiting
Shared decisions about antibiotics in the hospital
This study looks at how doctors and patients make decisions together about using antibiotics wisely in the hospital. If you are a patient who was treated with antibiotics for an infection while hospitalized, or a senior doctor who cares for such patients, this trial may be a fit.
Truro, CornwallAges 18 years+
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Common questions
- Are there clinical trials for antibiotics?
- Yes. Clin2 currently lists 296 recruiting antibiotics studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a antibiotics trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a antibiotics trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.