Clinical trials · Pennsylvania
Anxiety clinical trials in Pennsylvania
We’re tracking 29 recruiting anxiety studies with a site in Pennsylvania — including Phase 2 studies, each written for real people, not researchers.
Recruiting studies in Pennsylvania
- NCT06904508Recruiting
Therapy for anxiety in autistic youth from high-need communities
This trial tests whether cognitive behavioral therapy (CBT) can help reduce anxiety in autistic children and teens. It also looks at brain activity changes before and after therapy.
Philadelphia, PennsylvaniaAges 8–14 - NCT06809179RecruitingPhase 2
Nasal spray for social anxiety
This study tests if a new nasal spray called fasedienol helps quickly reduce anxiety in adults with social anxiety disorder. The spray is used as needed in a repeat-dose design, meaning you might use it more than once.
Plymouth Meeting, PennsylvaniaAges 18–65 - NCT05658796Recruiting
Program to reduce opioid use after hip or knee replacement
This trial tests a support program called RXWell to help people use less opioid pain medicine after elective hip or knee replacement surgery. It may help by addressing anxiety and depression symptoms that can affect pain and recovery.
Monroeville, PennsylvaniaAges 18–100 - NCT07707037Recruiting
Helping parents cope after a child's cardiac arrest
This study tests if providing clearer information to parents after their child's cardiac arrest can reduce fear and anxiety. It is for parents of children under 17.5 years old who are expected to leave the hospital soon.
Philadelphia, PennsylvaniaAges birth–17 years - NCT07649876Recruiting
Virtual Reality to Reduce Anxiety in Critically Ill Patients
This study tests whether wearing a virtual reality headset—which shows calming scenes like nature—can help reduce anxiety, agitation, and confusion in patients admitted to the intensive care unit. The goal is to see if VR can help patients feel more comfortable during their recovery.
Hershey, PennsylvaniaAges Any age - NCT07489651RecruitingPhase 2
New treatment for generalized anxiety disorder
This trial tests a new medication called RE104 for people with generalized anxiety disorder (GAD). The goal is to see if it helps reduce anxiety symptoms safely.
West Chester, PennsylvaniaAges 18–74 - NCT07288047Recruiting
Virtual reality for pain during early abortion
This study tests if using a virtual reality headset during a first trimester procedural abortion can help reduce pain and anxiety. You may be eligible if you are planning to have an abortion at Planned Parenthood of Western Pennsylvania and meet the criteria below.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT06846320RecruitingPhase 2
Study of ABBV-932 for generalized anxiety disorder
This trial tests an oral medicine called ABBV-932 when added to current antidepressant therapy for people with generalized anxiety disorder (GAD) who still have symptoms. It aims to see if the combination can improve anxiety and reduce side effects.
Allentown, PennsylvaniaAges 18–65 - NCT06783946Enrolling by invitation
Meditation for pain and anxiety after kidney stone surgery
This study is testing whether guided meditation can help reduce pain, discomfort, and anxiety after a kidney stone removal procedure called ureteroscopy. If you or your child is a teenager or adult scheduled for this surgery, meditation might be a calming tool to try before and after the procedure.
Philadelphia, PennsylvaniaAges 12 years+ - NCT06701903RecruitingPhase 2
Study of an investigational drug for generalized anxiety disorder
This study tests an investigational oral medication (ITI-1284) for people with moderate to severe generalized anxiety disorder (GAD) who haven't found enough relief from at least two standard medications. The goal is to see if this new drug helps reduce anxiety symptoms.
Media, PennsylvaniaAges 18 years+ - NCT06480383RecruitingPhase 2
Adding an experimental pill to current anxiety medication
This study tests an experimental medication (ITI-1284) added to your current anxiety treatment to see if it improves symptoms. It's for adults with generalized anxiety disorder (GAD) who haven't gotten enough relief from their current medicine.
Allentown, PennsylvaniaAges Any age - NCT04846777Recruiting
Phone-based support program for generalized anxiety
This study tests a brief treatment approach delivered through a smartphone app (or phone-based program) for people with generalized anxiety disorder. It may help you manage anxiety while also contributing to research on easier ways to get mental health support.
University Park, PennsylvaniaAges 18 years+ - NCT07436351Recruiting
ACT With CF Self-Help Toolkit
This trial tests an online self-help program based on acceptance and commitment therapy (ACT) for adults with cystic fibrosis who are feeling depressed or anxious. It aims to help you manage these feelings and improve your well-being.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07389473Recruiting
Studying eye movements in long-term psychiatric medication use (Gaize device)
This trial uses a special device (Gaize) to track how your eyes move while you take psychiatric medication. It aims to see how long-term medication affects eye patterns, which could help doctors better understand treatment responses.
Philadelphia, PennsylvaniaAges 18–65 - NCT07240792Recruiting
CBT for rural high school students with stress or mood issues
This study provides free cognitive-behavioral therapy (CBT) sessions led by college students to help rural high school students manage symptoms of depression, anxiety, or stress. It aims to see if this type of talk therapy can improve emotional well-being.
Hershey, PennsylvaniaAges 13–18 - NCT07219056Recruiting
Sound therapy for adults with trauma and addiction
This trial tests a sound-based program (Safe & Sound Protocol) to help adults with both trauma and substance use disorder in residential treatment. It aims to see if this gentle listening therapy can calm the nervous system and support recovery.
Wernersville, PennsylvaniaAges 18–75 - NCT07102147Recruiting
Telehealth Therapy for Lung Cancer Patients at Penn Medicine
This trial offers therapy sessions (via phone or video) for people with lung cancer who are dealing with depression, anxiety, or other emotional concerns. It's part of Penn Medicine's collaborative care program and aims to make mental health support easier to access while you are being treated for lung cancer.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07055906Recruiting
Video coaching to help Latino families talk about race
This study tests a video-based coaching program to help Latino parents and their 10–14-year-old children talk about race and ethnic background. Families will be recorded having a conversation, then get feedback to strengthen their communication.
Harrisburg, PennsylvaniaAges 10–14 - NCT06997549Recruiting
Review of mental health treatment outcomes
This study looks back at information from a large database of people who received mental health treatments. It aims to understand how well treatments worked and what factors influenced outcomes.
Malvern, PennsylvaniaAges 5–100 - NCT06917339Recruiting
A study looking at past treatment records
This trial looks back at medical records in the TrakStar database to understand how treatments were given. It does not test a new drug, but helps researchers learn from past treatment experiences.
Malvern, PennsylvaniaAges 5–120 - NCT06603064Recruiting
Brain stimulation study on stress and emotions
This study uses brain scans to understand how your brain responds to stress. You will complete tasks and answer questions while undergoing an MRI to help researchers learn more about emotional responses.
Pittsburgh, PennsylvaniaAges 30–50 - NCT06521398Recruiting
Postpartum Care for Preterm NICU Babies
This study focuses on helping new mothers of preterm babies (born before 34 weeks) who are getting care in the NICU at HUP. It tests a program to support your transition home after giving birth, so you and your baby can thrive.
Philadelphia, PennsylvaniaAges 16 years+ - NCT02463266Recruiting
PACE/PACENET program outcomes study for people 65+
This study looks at how well the PACE/PACENET care program works for older adults over time. If you join, you’ll provide consent for a check-in about your outcomes about 3 months after the acute (most intense) phase of care ends, with follow-up around 6 months.
Philadelphia, PennsylvaniaAges 65 years+ - NCT05800925Recruiting
Triage survey to check who can join psychiatry research
This study uses a short questionnaire to figure out who is eligible to join future psychiatry research. It may help people get routed into studies that match their situation and safety needs.
Philadelphia, PennsylvaniaAges 18 years+
Anxiety trials by city in Pennsylvania
Where these studies are running in Pennsylvania
Institutions with a site for the recruiting anxiety studies listed above.
- Suburban Research Associates · 3 studies
- Children's Hospital of Philadelphia · 2 studies
- Neuronetics · 2 studies
- University of Pennsylvania · 2 studies
- Abramson Cancer Center at the University of Pennsylvania
- Adams Clinical, Philadelphia
- Caron Treatment Centers
- Center for Family Planning Research, Magee-Womens Hospital
What taking part in a anxiety study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Anxiety trials in other states
Common questions
- Are there anxiety clinical trials in Pennsylvania?
- Yes. We're currently tracking 29 recruiting anxiety studies with a site in Pennsylvania, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a anxiety study in Pennsylvania?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Pennsylvania to take part?
- Not necessarily. These studies have a site in Pennsylvania, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a anxiety trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New anxiety studies open in Pennsylvania regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.