Clinical trials · California
Anxiety clinical trials in California
We’re tracking 59 recruiting anxiety studies with a site in California — including Phase 2 studies, each written for real people, not researchers.
Recruiting studies in California
- NCT06776991Recruiting
Social anxiety and public speaking fear study
This study tests if reward processing training combined with exposure therapy helps people with social anxiety disorder who are afraid of public speaking. Participants will complete therapy sessions and possibly an MRI brain scan.
Los Angeles, CaliforniaAges 18–60 - NCT06809179RecruitingPhase 2
Nasal spray for social anxiety
This study tests if a new nasal spray called fasedienol helps quickly reduce anxiety in adults with social anxiety disorder. The spray is used as needed in a repeat-dose design, meaning you might use it more than once.
Walnut Creek, CaliforniaAges 18–65 - NCT07771205Recruiting
Aromatherapy for surgical anxiety and pain
This study tests whether breathing in relaxing scents before surgery can reduce anxiety and pain. If effective, it could offer a simple, drug-free way to help you feel calmer during your procedure.
Stockton, CaliforniaAges 18 years+ - NCT06701903RecruitingPhase 2
Study of an investigational drug for generalized anxiety disorder
This study tests an investigational oral medication (ITI-1284) for people with moderate to severe generalized anxiety disorder (GAD) who haven't found enough relief from at least two standard medications. The goal is to see if this new drug helps reduce anxiety symptoms.
Culver City, CaliforniaAges 18 years+ - NCT07489651RecruitingPhase 2
New treatment for generalized anxiety disorder
This trial tests a new medication called RE104 for people with generalized anxiety disorder (GAD). The goal is to see if it helps reduce anxiety symptoms safely.
Garden Grove, CaliforniaAges 18–74 - NCT06480383RecruitingPhase 2
Adding an experimental pill to current anxiety medication
This study tests an experimental medication (ITI-1284) added to your current anxiety treatment to see if it improves symptoms. It's for adults with generalized anxiety disorder (GAD) who haven't gotten enough relief from their current medicine.
Glendale, CaliforniaAges Any age - NCT04557891Recruiting
Low-intensity ultrasound for generalized anxiety disorder
This trial tests a non-drug brain treatment using low-intensity focused ultrasound to reduce symptoms of generalized anxiety disorder (GAD). It may help if your anxiety has been moderate to severe and you’ve already tried standard medications without enough relief.
Los Angeles, CaliforniaAges 18–65 - NCT07511088Recruiting
Study of a supplement for mild stress in healthy adults
This study tests a dietary supplement for people who experience mild stress or anxiety at least once a week. You will fill out surveys on your phone or computer to see if the supplement helps you feel calmer.
San Francisco, CaliforniaAges 18–60 - NCT06526260Recruiting
Very Brief Exposure for Social Anxiety in Teens and Young Adults
This study tests a very short, new type of exposure therapy for social anxiety in teens and young adults. Participants will also have a brain scan (MRI) to see how the therapy affects the brain.
Los Angeles, CaliforniaAges 16–22 - NCT07390487Recruiting
Audio therapy for anxiety in people with psoriasis
This study tests whether listening to a short audio program (about 25–30 minutes) at home can help reduce anxiety in people with psoriasis. If you have psoriasis and have been feeling anxious, you may be able to take part from home using your computer or phone.
San Francisco, CaliforniaAges 18 years+ - NCT06269146RecruitingPhase 2
Pramipexole to improve social connections
This study tests if a medication called pramipexole can help people with anxiety or depression who also find it difficult to connect socially. It looks at whether the drug can improve your motivation for social interactions and help you feel more connected.
San Diego, CaliforniaAges 18–50 - NCT06376734RecruitingPhase 2
TMS for depression, anxiety, OCD, or schizophrenia
This study tests whether a brain stimulation technique called TMS can help people with depression, anxiety, OCD, or schizophrenia. It aims to find better ways to target the treatment for each person's specific needs.
Sunnyvale, CaliforniaAges 18–65 - NCT06714942Recruiting
Ashwagandha for stress and anxiety in adults
This trial tests whether a special ashwagandha root extract can help reduce stress and anxiety. If you're an adult dealing with high stress and have not been on related medications recently, you may be able to join.
San Francisco, CaliforniaAges 18–65 - NCT06846320RecruitingPhase 2
Study of ABBV-932 for generalized anxiety disorder
This trial tests an oral medicine called ABBV-932 when added to current antidepressant therapy for people with generalized anxiety disorder (GAD) who still have symptoms. It aims to see if the combination can improve anxiety and reduce side effects.
Colton, CaliforniaAges 18–65 - NCT06912854Recruiting
Sensory-adapted dental visits for children with fear of the dentist
This study tests whether a specially adapted dental environment (with calming sights and sounds) can make cleanings easier and less scary for children. It may help kids who are afraid of the dentist or not.
Los Angeles, CaliforniaAges 6–12 - NCT07310004Recruiting
VR vs Music for Breast Biopsy Anxiety
This trial compares using a virtual reality headset versus listening to relaxing music to help lower your anxiety and pain during a breast biopsy. Both methods are non-drug ways to help you feel more comfortable during the procedure.
Los Angeles, CaliforniaAges 18 years+ - NCT07323784RecruitingPhase 2
Study of NTX-1472 for social anxiety disorder
This trial tests an investigational medicine called NTX-1472 to see if it helps people with social anxiety disorder. Participation involves taking the study drug and attending scheduled visits.
Encino, CaliforniaAges 18–65 - NCT07430800Recruiting
AI-Powered CBT for Anxiety in University Students
This study tests whether personalized computer models can improve cognitive behavioral therapy (a talk therapy that helps change thinking patterns) for anxiety. It's for university students who have mild to moderate anxiety and are comfortable with being recorded during sessions.
Los Angeles, CaliforniaAges 18 years+ - NCT07441070Recruiting
Ashwagandha for stress and sleep in sexual and gender minorities
This study tests whether an Ashwagandha root extract supplement can help lower stress, anxiety, and improve sleep quality in adults who experience stress related to being a sexual or gender minority. You would take the supplement daily for a set period and report how you feel.
San Francisco, CaliforniaAges 18–45 - NCT06512324Enrolling by invitation
TMS with remote viewing for depression and anxiety
This trial tests whether adding 'remote viewing' (a technique where a person tries to perceive a distant target) to standard TMS brain stimulation can improve depression and anxiety symptoms. It is for people already getting TMS and who can attend weekly visits.
Encinitas, CaliforniaAges 12 years+ - NCT06935604Recruiting
Mindfulness VR for hospital patients
This trial tests whether a virtual reality (VR) program with calming mindfulness activities can help hospitalized patients feel less stressed and more at ease. It is designed for adults who are stable enough to be in a hospital and can use simple VR equipment.
Palo Alto, CaliforniaAges 18–99 - NCT03723928Recruiting
Blood test–guided monitoring for metastatic breast cancer treatment
This study checks whether specific blood “tumor marker” levels can help monitor how hormone receptor–positive, HER2-negative metastatic breast cancer responds to first-line therapy. It uses regular blood tests (and sometimes scans) to see if this marker-based monitoring is useful and reliable.
Irvine, CaliforniaAges 18 years+ - NCT06786572Recruiting
Mindfulness training for veterans with distress or physical symptoms
This trial tests a mindfulness program that helps you better understand body signals (interoception). It aims to reduce emotional or physical distress in veterans who struggle with these issues.
San Diego, CaliforniaAges 18 years+ - NCT07184294Recruiting
Massage therapy for anxiety during chemo
This study tests different types of massage therapy to see if they can help reduce anxiety while you are getting chemotherapy. It is for people who have already had at least one chemo session, feel anxious, and have at least six more infusions scheduled.
Irvine, CaliforniaAges 18 years+
Anxiety trials by city in California
Where these studies are running in California
Institutions with a site for the recruiting anxiety studies listed above.
- Excell Research Inc · 3 studies
- University of California, Los Angeles (UCLA) · 3 studies
- Children's Hospital Los Angeles · 2 studies
- NRC Research Institute · 2 studies
- San Francisco Research Institute · 2 studies
- Sun Valley Research Center · 2 studies
- Sunwise Clinical Research · 2 studies
- Acacia Clinics
What taking part in a anxiety study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Anxiety trials in other states
Common questions
- Are there anxiety clinical trials in California?
- Yes. We're currently tracking 59 recruiting anxiety studies with a site in California, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a anxiety study in California?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in California to take part?
- Not necessarily. These studies have a site in California, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a anxiety trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New anxiety studies open in California regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.