Clinical trials · California
Anxiety clinical trials in California
We’re tracking 59 recruiting anxiety studies with a site in California — including Phase 2 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies in California
- NCT06776991Recruiting
Social anxiety and public speaking fear study
This study tests if reward processing training combined with exposure therapy helps people with social anxiety disorder who are afraid of public speaking. Participants will complete therapy sessions and possibly an MRI brain scan.
Los Angeles, CaliforniaAges 18–60 - NCT06809179RecruitingPhase 2
Nasal spray for social anxiety
This study tests if a new nasal spray called fasedienol helps quickly reduce anxiety in adults with social anxiety disorder. The spray is used as needed in a repeat-dose design, meaning you might use it more than once.
Sherman Oaks, CaliforniaAges 18–65 - NCT07807865RecruitingPhase 3
Testing a new anxiety medication for safety
This study is testing a new medication for generalized anxiety disorder. It will check if the drug is safe and well-tolerated when taken alone or alongside your current anxiety treatment.
Los Angeles, CaliforniaAges 18 years+ - NCT07767903RecruitingPhase 3
Study of a new medicine for generalized anxiety disorder
This trial tests an investigational medication to see if it can reduce anxiety symptoms in adults with generalized anxiety disorder. Participants will receive the study drug and be monitored for safety and effectiveness.
Redlands, CaliforniaAges 18 years+ - NCT07771205Recruiting
Aromatherapy for surgical anxiety and pain
This study tests whether breathing in relaxing scents before surgery can reduce anxiety and pain. If effective, it could offer a simple, drug-free way to help you feel calmer during your procedure.
Stockton, CaliforniaAges 18 years+ - NCT06714942Recruiting
Ashwagandha for stress and anxiety in adults
This trial tests whether a special ashwagandha root extract can help reduce stress and anxiety. If you're an adult dealing with high stress and have not been on related medications recently, you may be able to join.
San Francisco, CaliforniaAges 18–65 - NCT07511088Recruiting
Study of a supplement for mild stress in healthy adults
This study tests a dietary supplement for people who experience mild stress or anxiety at least once a week. You will fill out surveys on your phone or computer to see if the supplement helps you feel calmer.
San Francisco, CaliforniaAges 18–60 - NCT07489651RecruitingPhase 2
New treatment for generalized anxiety disorder
This trial tests a new medication called RE104 for people with generalized anxiety disorder (GAD). The goal is to see if it helps reduce anxiety symptoms safely.
Garden Grove, CaliforniaAges 18–74 - NCT07441070Recruiting
Ashwagandha for stress and sleep in sexual and gender minorities
This study tests whether an Ashwagandha root extract supplement can help lower stress, anxiety, and improve sleep quality in adults who experience stress related to being a sexual or gender minority. You would take the supplement daily for a set period and report how you feel.
San Francisco, CaliforniaAges 18–45 - NCT07430800Recruiting
AI-Powered CBT for Anxiety in University Students
This study tests whether personalized computer models can improve cognitive behavioral therapy (a talk therapy that helps change thinking patterns) for anxiety. It's for university students who have mild to moderate anxiety and are comfortable with being recorded during sessions.
Los Angeles, CaliforniaAges 18 years+ - NCT07390487Recruiting
Audio therapy for anxiety in people with psoriasis
This study tests whether listening to a short audio program (about 25–30 minutes) at home can help reduce anxiety in people with psoriasis. If you have psoriasis and have been feeling anxious, you may be able to take part from home using your computer or phone.
San Francisco, CaliforniaAges 18 years+ - NCT07323784RecruitingPhase 2
Study of NTX-1472 for social anxiety disorder
This trial tests an investigational medicine called NTX-1472 to see if it helps people with social anxiety disorder. Participation involves taking the study drug and attending scheduled visits.
Encino, CaliforniaAges 18–65 - NCT07310004Recruiting
VR vs Music for Breast Biopsy Anxiety
This trial compares using a virtual reality headset versus listening to relaxing music to help lower your anxiety and pain during a breast biopsy. Both methods are non-drug ways to help you feel more comfortable during the procedure.
Los Angeles, CaliforniaAges 18 years+ - NCT06912854Recruiting
Sensory-adapted dental visits for children with fear of the dentist
This study tests whether a specially adapted dental environment (with calming sights and sounds) can make cleanings easier and less scary for children. It may help kids who are afraid of the dentist or not.
Los Angeles, CaliforniaAges 6–12 - NCT06846320RecruitingPhase 2
Study of ABBV-932 for generalized anxiety disorder
This trial tests an oral medicine called ABBV-932 when added to current antidepressant therapy for people with generalized anxiety disorder (GAD) who still have symptoms. It aims to see if the combination can improve anxiety and reduce side effects.
Anaheim, CaliforniaAges 18–65 - NCT06701903RecruitingPhase 2
Study of an investigational drug for generalized anxiety disorder
This study tests an investigational oral medication (ITI-1284) for people with moderate to severe generalized anxiety disorder (GAD) who haven't found enough relief from at least two standard medications. The goal is to see if this new drug helps reduce anxiety symptoms.
Culver City, CaliforniaAges 18 years+ - NCT06526260Recruiting
Very Brief Exposure for Social Anxiety in Teens and Young Adults
This study tests a very short, new type of exposure therapy for social anxiety in teens and young adults. Participants will also have a brain scan (MRI) to see how the therapy affects the brain.
Los Angeles, CaliforniaAges 16–22 - NCT06512324Enrolling by invitation
TMS with remote viewing for depression and anxiety
This trial tests whether adding 'remote viewing' (a technique where a person tries to perceive a distant target) to standard TMS brain stimulation can improve depression and anxiety symptoms. It is for people already getting TMS and who can attend weekly visits.
Encinitas, CaliforniaAges 12 years+ - NCT06480383RecruitingPhase 2
Adding an experimental pill to current anxiety medication
This study tests an experimental medication (ITI-1284) added to your current anxiety treatment to see if it improves symptoms. It's for adults with generalized anxiety disorder (GAD) who haven't gotten enough relief from their current medicine.
Glendale, CaliforniaAges Any age - NCT06376734RecruitingPhase 2
TMS for depression, anxiety, OCD, or schizophrenia
This study tests whether a brain stimulation technique called TMS can help people with depression, anxiety, OCD, or schizophrenia. It aims to find better ways to target the treatment for each person's specific needs.
Sunnyvale, CaliforniaAges 18–65 - NCT04557891Recruiting
Low-intensity ultrasound for generalized anxiety disorder
This trial tests a non-drug brain treatment using low-intensity focused ultrasound to reduce symptoms of generalized anxiety disorder (GAD). It may help if your anxiety has been moderate to severe and you’ve already tried standard medications without enough relief.
Los Angeles, CaliforniaAges 18–65 - NCT07792837Recruiting
Online intuitive eating program for pregnant women with obesity
This study tests an online program that helps pregnant women with obesity learn to eat intuitively, which means listening to their body's hunger and fullness signals instead of dieting. The goal is to support their well-being during pregnancy.
San Diego, CaliforniaAges 18 years+ - NCT07719205Recruiting
Pre-visit imagery for children's dental care
This trial tests a tactile pre-visit imagery strategy to help children aged 4 to 10 years who have never had dental treatment before. The goal is to see if it reduces anxiety and improves their first experience with a filling or crown.
Los Angeles, CaliforniaAges 4–10 - NCT07717723Recruiting
Support for caregivers of heart disease patients
This study tests a program to help caregivers of people with heart disease manage stress and challenges. It aims to support your mental health while caring for a loved one.
Sacramento, CaliforniaAges 18 years+
Anxiety trials by city in California
Where these studies are running in California
Institutions with a site for the recruiting anxiety studies listed above.
- Anderson Clinical Research · 2 studies
- CalNeuro Research · 2 studies
- Children's Hospital Los Angeles · 2 studies
- Excell Research · 2 studies
- San Francisco Research Institute · 2 studies
- University of California, Los Angeles · 2 studies
- Acacia Clinics
- Advanced Research Center /ID# 267874
What taking part in a anxiety study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Anxiety trials in other states
Common questions
- Are there anxiety clinical trials in California?
- Yes. We're currently tracking 59 recruiting anxiety studies with a site in California, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a anxiety study in California?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in California to take part?
- Not necessarily. These studies have a site in California, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a anxiety trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New anxiety studies open in California regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.