Clinical trials · Los Angeles, CA
Aortic Valve Insufficiency clinical trials in Los Angeles
We’re tracking 14 recruiting aortic valve insufficiency studies with a site in or near Los Angeles, each written for real people, not researchers.
Recruiting studies near Los Angeles
- NCT04153292Recruiting
Testing a valve procedure for severe mitral regurgitation
This trial studies a minimally invasive mitral valve repair/replacement approach for people with severe mitral regurgitation (leaky mitral valve) who are not good candidates for standard surgery or catheter options. It may help improve symptoms by treating the leaky valve when other treatments aren’t suitable.
Los Angeles, CaliforniaAges 18 years+ - NCT06465745Recruiting
AltaValve study for leaky mitral valve
This trial tests a new, less invasive device called the AltaValve to treat a leaky mitral valve. It is for people whose leak is severe enough to cause symptoms, but who cannot have standard surgery or a clip procedure.
Los Angeles, CaliforniaAges 18 years+ - NCT07413965Recruiting
Transcatheter vs surgical valve replacement for severe bicuspid aortic stenosis
This trial compares two ways to replace a narrowed heart valve in people with a bicuspid aortic valve. If you're 50 or older and need a new valve, this study can help figure out which approach works best.
Los Angeles, CaliforniaAges 50 years+ - NCT05172960Recruiting
Study of a new heart valve for severe aortic stenosis
This trial tests a new version of a heart valve (SAPIEN X4) placed without open-heart surgery. It's for people with severe aortic stenosis who have symptoms like shortness of breath or chest pain.
Los Angeles, CaliforniaAges Any age - NCT04097145Recruiting
Heart valve repair for severe leaking tricuspid valve
This trial tests a catheter-based procedure (done through the blood vessels) to repair a severely leaky tricuspid valve. It may help people with symptoms or past hospitalizations from tricuspid valve leakage who are higher-risk for standard surgery.
Los Angeles, CaliforniaAges 18 years+ - NCT06455787Recruiting
J-Valve study for leaky aortic valve patients
This study tests a new, less invasive device called J-Valve for people with severe aortic regurgitation (a leaky aortic valve). It is placed through a tube in the leg artery, avoiding open-heart surgery, and may help those who are at high risk for surgery.
Los Angeles, CaliforniaAges 18 years+ - NCT02318342Recruiting
Testing blood-thinner treatment for clogged aortic bioprosthetic valves
This study checks whether a blood-thinning medicine can treat problems with a bioprosthetic (man-made tissue) aortic valve. It focuses on valve “clots” that can happen after either a catheter-based or surgery-based valve replacement.
Los Angeles, CaliforniaAges 18 years+ - NCT03003299Recruiting
Valve replacement for failing aortic bioprosthetic valves
This trial studies a new “valve-in-valve” procedure to treat a failing aortic bioprosthetic valve. It may help people improve blood flow through the heart valve and reduce valve-related problems.
Los Angeles, CaliforniaAges Any age - NCT03142152Recruiting
Mitral valve implant for heart failure with leaky mitral valve
This trial tests whether a device called the Carillon Mitral Contour System can help people with heart failure caused by a mild-to-moderate leaky mitral valve. You’d be compared against a control group, and the goal is to improve heart failure symptoms and outcomes.
Los Angeles, CaliforniaAges 18 years+ - NCT06608823Recruiting
Comparing surgery vs. the Trilogy valve for aortic regurgitation
This trial compares a new less-invasive valve replacement (Trilogy TAVR) with standard open-heart surgery for people with significant aortic regurgitation. It aims to see which treatment works better for patients who are eligible for both procedures.
Los Angeles, CaliforniaAges Any age - NCT04634240Recruiting
Staged heart bypass plus TAVR versus TAVR alone
This study compares doing a staged coronary bypass (revascularization) along with a valve procedure (TAVR) versus doing TAVR and medical treatment alone. It aims to see which approach better helps people with both aortic valve narrowing and coronary artery disease.
Torrance, CaliforniaAges Any age - NCT05913908Recruiting
Valve procedure study for severe tricuspid leakage
This trial tests how well a new catheter-based valve system works for people with severe (or worse) tricuspid valve leaking who still have symptoms despite medicines. It aims to improve outcomes by treating the leaking valve without open-heart surgery, if your heart structure and overall health fit the study.
Thousand Oaks, CaliforniaAges 18 years+ - NCT05932615Enrolling by invitation
Testing a new transcatheter valve for aortic valve narrowing
This trial studies how safe and effective the NAVITOR valve is for treating narrowed aortic valves placed through a catheter (no open-heart surgery). It may be an option if you’re at intermediate-to-low surgical risk and meet heart ultrasound/CT measurements.
Thousand Oaks, CaliforniaAges 18 years+ - NCT05172973Recruiting
New valve procedure for failing aortic bioprosthetic valves
This trial studies whether a new transcatheter aortic valve (SAPIEN X4) is safe and works well in people whose previously implanted aortic valve is now failing. It may help reduce valve symptoms in higher-surgery-risk patients who are not good candidates for open-heart valve replacement.
Newport Beach, CaliforniaAges Any age
Hear when a new Aortic Valve Insufficiency trial opens near Los Angeles, CA
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Aortic Valve Insufficiency trials in other cities
Where these studies are running near Los Angeles
Institutions with a site for the recruiting aortic valve insufficiency studies listed above.
- Cedars-Sinai Medical Center · 8 studies
- Los Robles Regional Medical Center · 4 studies
- University of California, Los Angeles (UCLA) · 3 studies
- Hoag Memorial Hospital Presbyterian · 2 studies
- Kaiser Permanente Los Angeles Medical Center · 2 studies
- Kaiser Permanente Fontana Medical Center
- Keck Medicine of USC
- Memorial Care Hospital
What taking part in a aortic valve insufficiency study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Looking wider? See all recruiting aortic valve insufficiency studies in California.
Common questions
- Are there aortic valve insufficiency clinical trials near Los Angeles?
- Yes. We're currently tracking 14 recruiting aortic valve insufficiency studies with a site near Los Angeles, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a aortic valve insufficiency study near Los Angeles?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Los Angeles to take part?
- Not necessarily. These studies have a site near Los Angeles, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a aortic valve insufficiency trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New aortic valve insufficiency studies open near Los Angeles regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.