Clinical trials · Chicago, IL
Aortic Valve Stenosis clinical trials in Chicago
We’re tracking 11 recruiting aortic valve stenosis studies with a site in or near Chicago — including Phase 2/Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies near Chicago
- NCT05172960Recruiting
Study of a new heart valve for severe aortic stenosis
This trial tests a new version of a heart valve (SAPIEN X4) placed without open-heart surgery. It's for people with severe aortic stenosis who have symptoms like shortness of breath or chest pain.
Chicago, IllinoisAges Any age - NCT07230964Recruiting
Heart valve study using a non-invasive skin test
This trial tests a special skin test (impedance cardiography) that may detect heart muscle changes in people with aortic stenosis. It could help doctors decide when valve replacement is needed.
Chicago, IllinoisAges 18 years+ - NCT06455787Recruiting
J-Valve study for leaky aortic valve patients
This study tests a new, less invasive device called J-Valve for people with severe aortic regurgitation (a leaky aortic valve). It is placed through a tube in the leg artery, avoiding open-heart surgery, and may help those who are at high risk for surgery.
Chicago, IllinoisAges 18 years+ - NCT07001800RecruitingPhase 2/Phase 3
Slowing aortic valve disease with ataciguat
This trial tests a new pill, ataciguat, to slow down the progression of moderate calcific aortic valve stenosis (a condition where your aortic valve stiffens). If you have moderate valve narrowing and meet the other criteria, participation could help find a way to delay needing surgery.
Chicago, IllinoisAges 50 years+ - NCT05932615Enrolling by invitation
Testing a new transcatheter valve for aortic valve narrowing
This trial studies how safe and effective the NAVITOR valve is for treating narrowed aortic valves placed through a catheter (no open-heart surgery). It may be an option if you’re at intermediate-to-low surgical risk and meet heart ultrasound/CT measurements.
Chicago, IllinoisAges 18 years+ - NCT04634240Recruiting
Staged heart bypass plus TAVR versus TAVR alone
This study compares doing a staged coronary bypass (revascularization) along with a valve procedure (TAVR) versus doing TAVR and medical treatment alone. It aims to see which approach better helps people with both aortic valve narrowing and coronary artery disease.
Chicago, IllinoisAges Any age - NCT03003299Recruiting
Valve replacement for failing aortic bioprosthetic valves
This trial studies a new “valve-in-valve” procedure to treat a failing aortic bioprosthetic valve. It may help people improve blood flow through the heart valve and reduce valve-related problems.
Chicago, IllinoisAges Any age - NCT04889872Recruiting
Watchful waiting or TAVR for moderate aortic valve narrowing
This study compares regular monitoring (“clinical surveillance”) versus replacing the aortic valve using a minimally invasive procedure called TAVR for people with moderate aortic stenosis. It aims to see which approach better reduces symptoms or heart damage over time.
Chicago, IllinoisAges 65 years+ - NCT06608823Recruiting
Comparing surgery vs. the Trilogy valve for aortic regurgitation
This trial compares a new less-invasive valve replacement (Trilogy TAVR) with standard open-heart surgery for people with significant aortic regurgitation. It aims to see which treatment works better for patients who are eligible for both procedures.
Chicago, IllinoisAges Any age - NCT05172973Recruiting
New valve procedure for failing aortic bioprosthetic valves
This trial studies whether a new transcatheter aortic valve (SAPIEN X4) is safe and works well in people whose previously implanted aortic valve is now failing. It may help reduce valve symptoms in higher-surgery-risk patients who are not good candidates for open-heart valve replacement.
Evanston, IllinoisAges Any age - NCT07556523RecruitingPhase 4
Recovery quality after heart valve replacement with different sedation
This study compares how well patients recover after a minimally invasive heart valve procedure (TAVR) when given different types of sedation. The goal is to find which sedation approach helps patients feel better and recover faster after the procedure.
Glenview, IllinoisAges 18–90
Hear when a new Aortic Valve Stenosis trial opens near Chicago, IL
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Aortic Valve Stenosis trials in other cities
Where these studies are running near Chicago
Institutions with a site for the recruiting aortic valve stenosis studies listed above.
- Northwestern University · 5 studies
- Ascension Alexian Brothers · 3 studies
- Endeavor Health - Glenbrook Hospital · 3 studies
- Rush University Medical Center · 3 studies
- Alexian Brothers Hospital · 2 studies
- NorthShore University HealthSystem-Evanston Hospital · 2 studies
- Endeavor Health
- Heart Care Centers of Illinois / Hinsdale Hospital
What taking part in a aortic valve stenosis study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Looking wider? See all recruiting aortic valve stenosis studies in Illinois.
Common questions
- Are there aortic valve stenosis clinical trials near Chicago?
- Yes. We're currently tracking 11 recruiting aortic valve stenosis studies with a site near Chicago, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a aortic valve stenosis study near Chicago?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Chicago to take part?
- Not necessarily. These studies have a site near Chicago, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a aortic valve stenosis trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New aortic valve stenosis studies open near Chicago regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.