Slowing aortic valve disease with ataciguat
Part of Heart & circulation clinical trials.
This trial tests a new pill, ataciguat, to slow down the progression of moderate calcific aortic valve stenosis (a condition where your aortic valve stiffens). If you have moderate valve narrowing and meet the other criteria, participation could help find a way to delay needing surgery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 50 years old or older
- You have moderate calcific aortic valve stenosis with specific valve area and calcium scores
- Your heart's pumping ability (ejection fraction) is 45% or better
- You are not planning to have aortic valve surgery in the next 6 months
- You do not have certain other heart valve problems or congenital valve disease
- You do not have certain types of cardiomyopathy or untreated blocked coronary arteries
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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