Clinical trials
Arteriovenous Malformations clinical trials
Below are recruiting arteriovenous malformations clinical trials, each written for real people, not researchers. We’re tracking 33 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03676868Recruiting
Study of brain blood vessel malformations and outcomes
This study looks at how brain arteriovenous malformations (abnormal connections between arteries and veins in the brain) behave over time, and how different treatment choices affect outcomes. It may help researchers better predict prognosis and guide future care.
ParisAges birth+ - NCT05983159RecruitingPhase 2
Targeted therapy for slow-flow or fast-flow vascular malformations
This trial tests two targeted medicines for people with certain types of vascular malformations (abnormal blood vessels). If you have a slow-flow malformation, you may receive alpelisib; if you have a fast-flow malformation, you may receive mirdametinib. Genetic testing is needed to see if your malformation has a specific change that these drugs target.
Parkville, VictoriaAges 2 years+ - NCT07314047Recruiting
A study of a liquid gel for brain AVM treatment
This trial tests a liquid embolic agent (a gel-like material) injected into the blood vessels of a brain arteriovenous malformation (AVM) to block abnormal blood flow. It’s for people aged 18 to 80 with certain types of AVMs that doctors think can be treated this way.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT02098252Recruiting
Study for treating brain blood vessel malformations (AVMs)
This study is looking at treatment options for people who have an abnormal cluster of blood vessels in the brain (an AVM). It may help participants by offering a structured treatment approach, depending on the AVM type and recent symptoms.
Jacksonville, FloridaAges 5 years+ - NCT02042326RecruitingPhase 2
Sirolimus trial for severe arteriovenous malformations
This trial studies whether sirolimus (Rapamune®) can reduce problems from severe arteriovenous malformations (tangled blood vessel connections). It may help shrink the abnormal vessels or improve symptoms, by testing the medicine in people with certain AVM types.
BrusselsAges 2 years+ - NCT02879071Recruiting
Follow-up after blocking abnormal brain blood vessels
This study checks people long-term after a procedure called embolization, which blocks abnormal blood vessel connections in the brain (arteriovenous malformations). It may help doctors learn how well the treatment lasts over time and what outcomes to expect.
ParisAges 18 years+ - NCT06913725RecruitingPhase 2
Testing FCN-159 for Brain AVM
This trial tests an oral medication called FCN-159 for people with a high-grade brain AVM that has never bled. The goal is to see if it can shrink the AVM or prevent future problems.
Beijing, Beijing MunicipalityAges 18–60 - NCT06735976Recruiting
Safety and effectiveness of LOBO device for PAVM treatment
This study tests a new device (LOBO™) to block abnormal blood vessels in the lungs called PAVMs. It is for people with HHT or similar conditions, and the device is placed into the vessel to reduce the risk of stroke or bleeding. You may be able to join if you have a suitable PAVM that is large enough and you are not taking blood thinners.
Chapel Hill, North CarolinaAges 14 years+ - NCT06259292Recruiting
HHT patient registry tracking long-term outcomes
This registry collects health information from people with HHT over time to better understand the disease and improve care. Joining does not involve any experimental treatment, but your data will help researchers learn more about HHT.
Birmingham, AlabamaAges Any age - NCT07118631Recruiting
Emergency surgery for bleeding brain blood vessel malformation
This study tests emergency surgery for patients with bleeding from a brain blood vessel malformation (AVM). It aims to see if urgent surgery can help people with this type of stroke.
BeijingAges 18–70 - NCT04772963Recruiting
Genetics study for brain blood vessel malformations
This study looks at genetic (inherited DNA) factors in people with certain abnormal blood vessel connections in the brain or spinal cord. It may help researchers understand why these malformations happen and how they might behave over time.
ParisAges Any age - NCT04572568Recruiting
Registry to study care for brain blood vessel malformations
This study collects medical and imaging information from people with a brain arteriovenous malformation (AVM) to understand how different treatments are used in real life. It may help doctors improve future care, even if you are not receiving a new drug in this study.
Beijing, Beijing MunicipalityAges 1–80 - NCT07569887Recruiting
Brain Imaging Study of Arteriovenous Malformations Before and After Surgery
This research study uses special brain imaging scans to understand how an unruptured arteriovenous malformation (an abnormal tangle of blood vessels in the brain) affects blood flow and thinking abilities before and after surgical treatment. The goal is to learn how surgery impacts brain function and cognition in patients like you.
Montpellier, FranceAges 18 years+ - NCT06479343Recruiting
Liquid embolic for brain vessel malformations
This trial tests a new liquid material (called a liquid embolic system) that is injected into the abnormal blood vessels in the brain to block them off. It is for people who have a cerebrovascular malformation and can be treated with a catheter from inside the blood vessel.
Guangzhou, GuangdongAges 18–80 - NCT04927156Recruiting
Check safety and use of Balt medical devices after treatment
This post-marketing study follows people after they receive Balt medical devices to make sure the devices are safe, work well, and are easy to use in real life. You may be considered if you can consent and your procedure matches their device-use rules.
AngersAges 2 years+ - NCT06099015Recruiting
Cera vascular plug study for blocking blood vessels
This study tests a device called the Cera Vascular Plug System to block blood flow in certain arteries or veins. It may help patients who need this type of treatment for conditions like abnormal blood vessels or bleeding.
Bad HersfeldAges 18–85 - NCT06264531RecruitingPhase 2/Phase 3
Bevacizumab for adults with symptomatic, untreatable brain AVMs
This trial tests a medication called bevacizumab (given as an IV infusion) to see if it can improve symptoms in people with brain arteriovenous malformations (AVMs) that cannot be treated with standard therapies. It is for those whose AVMs cause significant disability.
Paris, Île-de-France RegionAges 18 years+ - NCT07639853Enrolling by invitation
Doctor feedback survey on Concerto Versa coils
This study gathers feedback from doctors who use Concerto Versa detachable coils (small metal devices that help treat brain aneurysms). The survey helps improve how these coils work and are used.
El Paso, TexasAges 22 years+ - NCT07525518Enrolling by invitation
Okami Medical Device Patient Registry
This is a registry—a database that tracks patient outcomes—for people receiving Okami Medical devices. By joining, you help doctors understand how well these devices work and whether they're safe over time.
Aurora, ColoradoAges 18 years+ - NCT05449106Recruiting
Medical-only care study for unruptured brain AVMs
This study looks at outcomes for people with an unruptured brain arteriovenous malformation (AVM) using medical care only, without procedures. It may help doctors understand which medical approach and monitoring works best for different AVM locations seen on CT scans.
Beijing, Beijing MunicipalityAges 3–80 - NCT03731000Recruiting
Testing a glue-like treatment for abnormal brain vessel leaks in children
This trial studies a device that delivers a special “embolic” material (often described as glue) to treat a type of abnormal connection in the brain’s blood vessels (dAVF). It may help by blocking the leaking or risky blood flow, and it will be compared against how doctors handle eligible cases with other embolic materials.
New York, New YorkAges Up to 21 years - NCT04194619Recruiting
Study of pregnancy safety in women with rare blood-vessel diseases
This study looks at pregnancy and the early period after birth in women with rare diseases that affect blood vessels. It may help doctors understand risks and improve care for future pregnancies.
AngersAges 18–45 - NCT04888936Recruiting
Study families with genetic RAS syndromes, including adults and children
This study looks at people with certain inherited genetic conditions called RASopathies and their family members. It helps researchers understand these conditions and how genetic changes run in families, which may improve future care.
Bethesda, MarylandAges 1 month–99 years - NCT05477680Recruiting
Measuring brain shift during surgery using navigation
This study tests whether a special brain-navigation method can better measure how the brain moves during surgery for certain brain conditions. If it works, it may help surgeons avoid mistakes caused by brain shifting while you are under anesthesia.
MoscowAges 18–100
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Common questions
- Are there clinical trials for arteriovenous malformations?
- Yes. Clin2 currently lists 33 recruiting arteriovenous malformations studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a arteriovenous malformations trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a arteriovenous malformations trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.