Sirolimus trial for severe arteriovenous malformations
Treatments studied
Part of Genetic & congenital, Heart & circulation clinical trials.
This trial studies whether sirolimus (Rapamune®) can reduce problems from severe arteriovenous malformations (tangled blood vessel connections). It may help shrink the abnormal vessels or improve symptoms, by testing the medicine in people with certain AVM types.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have an arteriovenous malformation (AVM) that is stage II/III or IV, active or not
- You (or your parent/guardian) can understand the study and sign consent
- If you can become pregnant, you must use reliable birth control during the study and for 12 weeks after
- If you can become pregnant, your pregnancy test must be negative
- You must be able to have MRI scans as part of the study
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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