Clinical trials
Arthritis clinical trials
Below are recruiting arthritis clinical trials, each written for real people, not researchers. We’re tracking 540 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06726096Enrolling by invitationPhase 3
Trial of VDJ001 for moderate to severe rheumatoid arthritis
This trial tests a new medicine called VDJ001 for people with moderate to severe rheumatoid arthritis who are already taking methotrexate. The goal is to see if VDJ001 helps reduce joint pain and swelling better than a placebo.
Beijing, Beijing MunicipalityAges 18–75 - NCT06686082Enrolling by invitation
Biologic therapy for early psoriatic arthritis
This study looks at whether starting biologic treatments early, even before joint pain appears, can help people with psoriasis who have signs of joint inflammation on ultrasound. You may be eligible if you have moderate to severe psoriasis but no joint symptoms yet.
Fuzhou, FujianAges 18 years+ - NCT06671054RecruitingPhase 2
Testing AP1189 for newly diagnosed active rheumatoid arthritis
This study tests an oral drug called AP1189 for people just diagnosed with active rheumatoid arthritis who haven't yet taken standard arthritis medicines. You may be able to take part if your disease is very active and you're ready to try a new treatment option.
Cutler Bay, FloridaAges 18 years+ - NCT06671483RecruitingPhase 3
Zasocitinib for psoriatic arthritis without prior biologic use
This trial tests an oral medication called zasocitinib for adults with psoriatic arthritis who have not tried biologic medicines before. It aims to see if the drug can improve joint pain, swelling, and skin symptoms.
Chandler, ArizonaAges 18 years+ - NCT06663332RecruitingPhase 3
Long-term study of guselkumab in children who previously took it
This study is a long-term follow-up for children who have already finished an earlier study of guselkumab, a medicine for skin conditions like psoriasis. It looks at whether staying on the medicine continues to be safe and helpful over time.
Atlanta, GeorgiaAges 3 years+ - NCT06658821Enrolling by invitation
Study of LDL557 for knee arthritis in older adults
This trial tests whether a supplement called LDL557 can improve early-stage knee arthritis in people over 65. It aims to reduce pain and slow joint damage.
TaichungAges 45–80 - NCT06654882RecruitingPhase 3
Comparing next treatments for juvenile arthritis after a first biologic
This study tests different arthritis medications given in sequence for children and young adults with polyarticular JIA who did not get enough relief from a first TNF inhibitor. It aims to find which next treatment works best and is safe.
San Francisco, CaliforniaAges 2–21 - NCT06649136RecruitingPhase 4
Optimizing methotrexate for active rheumatoid arthritis
This study tests whether increasing the dose of methotrexate or switching from pills to injections can better control rheumatoid arthritis symptoms. It aims to find the best way to use this common medication to reduce joint pain and swelling.
Vienna, State of ViennaAges 18–99 - NCT06631638Recruiting
New hip replacement study using smart navigation
This study tests a hip replacement system that uses a special navigation tool to help the surgeon place the new hip cup more precisely. It may lead to better long-term results and fewer complications.
Gainesville, FloridaAges 21 years+ - NCT06596031Enrolling by invitation
Health coaching for people waiting for hip or knee replacement
This study tests whether health coaching can help people who are waiting for hip or knee replacement surgery. It aims to improve your health and wellbeing while you wait for your operation.
SheffieldAges 18 years+ - NCT06469177Enrolling by invitation
Pain management app study for joint replacement recovery
This study tests a smartphone tool to help manage pain after hip, knee, or shoulder replacement. It aims to see if using the tool improves your recovery compared to standard care.
Dartmouth, Nova ScotiaAges 19 years+ - NCT05534347Recruiting
Blood marker study in teens with juvenile arthritis
This study looks at blood (and related) markers that may reflect inflammation in people with juvenile idiopathic arthritis. It may help doctors better understand disease activity and guide future care for patients who are able to join.
Paris, IDFAges 16 years+ - NCT06382051Recruiting
Improving Psoriatic Arthritis Screening in Psoriasis
This study tests a new way to screen for psoriatic arthritis (a type of joint inflammation) in people with psoriasis. It looks at a tool called PEST and aims to improve early detection.
Calgary, AlbertaAges 18 years+ - NCT06301373Recruiting
Combining methotrexate and tofacitinib for rheumatoid arthritis
This study tests whether combining two medicines—methotrexate and tofacitinib—works better for people with a specific type of rheumatoid arthritis. It may be a good fit if you have moderate to severe arthritis, have had a joint biopsy that shows a certain cell pattern, and haven't used similar treatments before.
Foshan, GuangdongAges 18–65 - NCT05716737Recruiting
Radiation treatment study for TMJ arthritis pain
This study looks at how radiotherapy (radiation treatment) may help people with arthritis in the jaw joint (TMJ). It will only consider patients whose TMJ arthritis was diagnosed by a dentist or surgeon and who have not had radiation to that area before.
ViennaAges 50–100 - NCT06235645Recruiting
Detecting lung disease in rheumatoid arthritis with ultrasound
This study tests if a lung ultrasound can detect early signs of lung disease in people with rheumatoid arthritis. It may help you if you have certain risk factors, like being male, older, or a smoker.
ToursAges 18 years+ - NCT05413759Recruiting
Helping rheumatoid arthritis patients take medicines on schedule
This study looks at how well people with rheumatoid arthritis (RA) take their RA medicines—especially medicines like methotrexate and other targeted or biologic treatments. It may help improve medication adherence (taking doses correctly) and supports safer, more consistent treatment at home.
Pierre-Bénite, LyonAges 18 years+ - NCT05428488RecruitingPhase 3
Step-by-step treatment for rheumatoid arthritis with TNF medicine
This trial tests a step-by-step plan for treating rheumatoid arthritis when current medicines aren’t controlling the disease. It compares how well a targeted approach works by adjusting treatment for people who need a TNF inhibitor.
Montpellier, FranceAges 18 years+ - NCT06201416RecruitingPhase 1
Single dose of SBT777101 for rheumatoid arthritis
This study tests a single dose of an experimental drug called SBT777101 for people with moderate to severe rheumatoid arthritis who have already tried and failed at least two advanced treatments. The goal is to see if it is safe and how the body handles it.
Scottsdale, ArizonaAges 18–70 - NCT06100744RecruitingPhase 3
Comparing two drugs for children with psoriatic arthritis
This study tests two drugs—risankizumab and adalimumab—to see which is safer and works better for children with active psoriatic arthritis. It's for kids who have not been helped enough by standard disease-modifying drugs.
Little Rock, ArkansasAges 5–17 - NCT06037811RecruitingPhase 2
Adalimumab for Immunotherapy-Related Arthritis
This study tests if a medicine called adalimumab (a type of TNF blocker) can help with new joint pain and swelling (inflammatory arthritis) caused by some immunotherapy drugs. It aims to reduce the need for high-dose steroids and improve symptoms.
London, OntarioAges 18 years+ - NCT05966519Recruiting
Study testing flexible planning for knee replacement with ROSA
This study looks at how flexible pre-op planning can be when you get a total knee replacement using the ROSA system. It may help doctors fine-tune surgery planning while keeping outcomes safe and effective.
Fukuoka, FukuokaAges 20 years+ - NCT05961592RecruitingPhase 1
Study drug R-2487 for people with active rheumatoid arthritis
This Phase 1 study tests how the drug R-2487 behaves in the body and looks at early safety in adults with active rheumatoid arthritis. If you have ongoing joint inflammation despite standard treatments, this trial may offer a chance to try an investigational therapy under close monitoring.
San Diego, CaliforniaAges 18–75 - NCT05925452Recruiting
Genalumab for children with active systemic juvenile arthritis
This trial studies whether a medicine called genalumab can reduce inflammation and improve symptoms in children with active systemic juvenile idiopathic arthritis (sJIA). It also checks how safe the treatment is, including possible side effects.
Beijing, BenjingAges 2–17
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Common questions
- Are there clinical trials for arthritis?
- Yes. Clin2 currently lists 540 recruiting arthritis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a arthritis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a arthritis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.