Clinical trials
Arthritis clinical trials
Below are recruiting arthritis clinical trials, each written for real people, not researchers. We’re tracking 540 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06533423Recruiting
Self-management help for new arthritis patients
This trial tests a self-management program for people recently diagnosed with certain types of arthritis. It aims to help you better manage your condition through education and support.
Glostrup MunicipalityAges 18–120 - NCT06454188RecruitingPhase 4
Upadacitinib for Psoriatic Arthritis with Spine Involvement
This study tests how well upadacitinib (a pill taken daily) works for people with active psoriatic arthritis that also affects the spine. It is for those who have not responded well enough to other treatments like NSAIDs or biologics.
Cleveland, OhioAges 18 years+ - NCT06359665Enrolling by invitationPhase 1
Oral curcumin for thumb arthritis pain
This trial tests whether an oral curcumin supplement can help reduce pain from thumb arthritis. If you are an adult with daily thumb pain of at least moderate severity and have not taken turmeric or blood thinners, this may be an option for you.
Charlottesville, VirginiaAges 18 years+ - NCT05754710Recruiting
Kids taking Xeljanz for juvenile arthritis study
This study is collecting real-world information about how Xeljanz (tofacitinib) is used and how well it works in children with juvenile idiopathic arthritis. It may help improve how the medicine is used safely in everyday care.
SeoulAges 2–17 - NCT04806620Recruiting
Online app study for brain inflammation lifestyle data
This study uses a digital platform (app/website) to collect lifestyle and symptom information to better understand brain inflammation. You may qualify if you have certain conditions like Long COVID, migraines, autoimmune disease, inflammatory gut issues, mood disorders, or if you are a healthy comparison person.
Delafield, WisconsinAges 2 years+ - NCT04402086Recruiting
Rheumatology patient and skin sample registry study at Yale
This study builds a health record and blood/skin sample collection for people with rheumatic autoimmune diseases who are getting care at Yale. It may help researchers understand these conditions and develop better tests or treatments over time.
New Haven, ConnecticutAges 18–99 - NCT03768271Recruiting
Study of early psoriatic arthritis for better diagnosis and care
This study follows people with a first episode of peripheral (hand/foot/arm/leg) arthritis that seems to be psoriatic arthritis. It aims to improve understanding of early disease and may help guide more personalized care over time.
CréteilAges 18–65 - NCT03510442Recruiting
Study of genetics and causes of systemic juvenile arthritis and Still's disease
This study aims to learn more about the causes and genetics of two related inflammatory conditions: systemic juvenile idiopathic arthritis (sJIA) in children and adult-onset Still's disease (AOSD) in adults. By studying patients and healthy volunteers, researchers hope to understand these diseases better and find better ways to treat them.
Bethesda, MarylandAges 1 day–100 years - NCT02469662Recruiting
Study of outcomes after Nexel total elbow replacement
This study looks at how well the Nexel total elbow replacement works over time for people who need an elbow replacement due to pain, damage, or instability. It may help the doctors understand which patients benefit most and what results to expect.
Golden, ColoradoAges 18 years+ - NCT07878975Recruiting
Heart rate variability tracking for rheumatoid arthritis
This study uses a smart ring to track your heart rate variability (a measure of heart health) while you sleep, to see if it relates to rheumatoid arthritis activity. You would wear the ring at night and complete short weekly check-ins for about three months.
Orlando, FloridaAges 18 years+ - NCT07620392RecruitingPhase 2
Long-Term Safety Study of Afimkibart for Rheumatoid Arthritis
This is a follow-up study for people who already completed a previous trial testing afimkibart (an experimental drug) for rheumatoid arthritis. It checks whether the drug continues to work safely and effectively over a longer period.
Tamarac, FloridaAges 18 years+ - NCT07137598RecruitingPhase 2
A study of RO7790121 for moderate to severe rheumatoid arthritis
This study tests a new drug, RO7790121, for people with rheumatoid arthritis (RA) who have not gotten better with or could not tolerate common treatments like TNF inhibitors or JAK inhibitors. It aims to see if the drug is safe and can help reduce joint pain and swelling.
Avondale, ArizonaAges 18 years+ - NCT07453004RecruitingPhase 2
Study of plonmarlimab for frequent gout attacks
This trial tests a new investigational drug called plonmarlimab for people with frequent, painful gout flares who cannot take standard treatments. The goal is to see if it can reduce pain and inflammation from the flare.
Bengbu, AnhuiAges 18 years+ - NCT07607964RecruitingPhase 1
ABBV-519 Study for Lupus or Rheumatoid Arthritis
This early-stage trial tests a new drug called ABBV-519 given as infusions or injections to treat systemic lupus erythematosus (SLE) or rheumatoid arthritis (RA) in adults whose disease hasn't responded well to other treatments. Researchers will measure how safe the drug is, how it moves through your body, and whether it helps reduce symptoms.
Anniston, AlabamaAges 18–75 - NCT05062421Recruiting
Study how well arthritis treatments keep working over time
This study looks at people with adult rheumatoid arthritis to see how long biological medicines and “JAK inhibitors” keep helping. It uses routine clinic follow-up records to understand how well treatment persists over time and how outcomes change.
SevilleAges 18 years+ - NCT05391100Recruiting
Screening people with rheumatoid arthritis for lung scarring
This study looks for early lung scarring in people who have rheumatoid arthritis. It may help find a serious lung condition earlier so doctors can watch or treat it sooner.
BudapestAges 40 years+ - NCT05657847Recruiting
Imaging tests for joint disease in arthritis
This study tests new kinds of imaging (radiology pictures) to help understand arthritis in joints. It may help improve how these arthritis types are identified and followed over time.
BudapestAges 18–100 - NCT03048201Recruiting
Total Knee Replacement Registry Study for a Specific Knee Implant
This study tracks outcomes for people getting a total knee replacement using a specific knee implant system. It may help doctors understand which patients do best and how the implant performs over time.
Rancho Mirage, CaliforniaAges 22 years+ - NCT05883371Recruiting
IMPACT autoimmune study registry for people on biologic medicines
This study is a registry that collects health information from adults with certain autoimmune conditions who are currently using (or have been recommended) biologic or DMARD medicines. It may help researchers better understand these diseases and how treatments affect people over time.
Columbus, OhioAges 18–70 - NCT05954364Recruiting
Study of advanced treatments for psoriatic arthritis based on sex and gender
This study looks at how well advanced treatments work for people with psoriatic arthritis, and whether results differ for sex and gender. You may be eligible if your psoriatic arthritis is active and you are planning to start an advanced treatment for symptoms in the joints and surrounding areas.
Toronto, OntarioAges 18 years+ - NCT05719935Recruiting
KinematX wrist replacement registry for people with wrist arthritis
This trial is a registry that follows people who get (or already had) a KinematX total wrist replacement. It collects health and recovery information to better understand outcomes for different wrist problems, like arthritis or certain bone alignment issues.
Loma Linda, CaliforniaAges 18–85 - NCT07866326Recruiting
Adrenal function in rheumatoid arthritis patients on low-dose steroids
This study looks at how well your adrenal glands work if you have rheumatoid arthritis and are taking a low dose of corticosteroids (steroids). It aims to see if these treatments affect your adrenal function and to identify what factors might be linked to any problems.
Bursa, YıldırımAges 18–65 - NCT01965132Recruiting
Biologic and targeted therapy registry for arthritis patients
This registry is collecting information about people with rheumatoid arthritis, ankylosing spondylitis, or psoriatic arthritis who are starting or needing biologic or targeted medicines. It may help researchers better understand how these treatments work in real life.
SeoulAges 18 years+ - NCT07828080Recruiting
Hip replacement using a newer stem design
This study looks at how well a newer type of hip replacement stem (called the Actis stem) works for people having their first hip replacement. It aims to see if this stem provides good outcomes for various hip conditions.
Seongnam-si, Gyeonggi-doAges 18 years+
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Common questions
- Are there clinical trials for arthritis?
- Yes. Clin2 currently lists 540 recruiting arthritis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a arthritis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a arthritis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.