Clinical trials
Arthritis clinical trials
Below are recruiting arthritis clinical trials, each written for real people, not researchers. We’re tracking 550 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05619588Recruiting
Long-term follow-up for a new ankle replacement (U.S. only)
This study checks how well an Exactech total ankle replacement works over many years. You may be asked to complete follow-up forms for up to 10 years to help track safety and outcomes.
Jacksonville, FloridaAges 21 years+ - NCT04629391Recruiting
Reverse vs standard shoulder replacement for arthritis
This study compares two types of shoulder replacement surgery for people with arthritis and an intact rotator cuff. The goal is to see which operation works better and is more reliable for your type of shoulder problem.
MeyrinAges 65–85 - NCT07409103RecruitingPhase 2
Testing ELV001 for active rheumatoid arthritis
This study tests a new medication, ELV001, for people with active rheumatoid arthritis who haven't improved enough with methotrexate and a TNF inhibitor. The goal is to see if different doses of ELV001 are safe and can help reduce joint pain and swelling.
Gilbert, ArizonaAges 18–75 - NCT07533955RecruitingPhase 1
Testing JADE201 drug in rheumatoid arthritis patients
This early-stage study tests a new drug called JADE201 in people with rheumatoid arthritis (RA). Researchers want to see if it is safe and how the body handles it, which could lead to better RA treatments.
Chisinau, MoldovaAges 18–70 - NCT07388407Recruiting
Genetics of leflunomide for rheumatoid arthritis
This study looks at how your genes might affect how well leflunomide works for rheumatoid arthritis. It is for Pakistani adults who are starting or recently started leflunomide, and will help doctors understand who might respond best.
Islamabad, Punjab ProvinceAges 20–65 - NCT05824845Recruiting
Join a study collecting information for hip or knee replacement care
This study asks people in the UK who are getting their first hip or knee replacement to answer questionnaires and let researchers use linked health data. The goal is to improve understanding of outcomes and help set up future studies for better care.
AshingtonAges 18 years+ - NCT05925452Recruiting
Genalumab for children with active systemic juvenile arthritis
This trial studies whether a medicine called genalumab can reduce inflammation and improve symptoms in children with active systemic juvenile idiopathic arthritis (sJIA). It also checks how safe the treatment is, including possible side effects.
Beijing, BenjingAges 2–17 - NCT07744542Enrolling by invitation
Physical therapy for shoulder arthritis pain
This study tests if a specific physical therapy program can help people with shoulder arthritis (wear-and-tear in the shoulder joint) feel better and move more easily without surgery. It may help you if you have this type of arthritis and have not tried physical therapy recently.
Buffalo, New YorkAges 18 years+ - NCT06913088Recruiting
Ultrasound bubbles bandage for hand arthritis
This trial tests a special bandage that uses ultrasound and tiny bubbles to treat arthritis pain and stiffness in your hands. If you have hand arthritis with at least three painful finger or wrist joints, you may be able to join.
Taichung, TaichungAges 20 years+ - NCT06596031Enrolling by invitation
Health coaching for people waiting for hip or knee replacement
This study tests whether health coaching can help people who are waiting for hip or knee replacement surgery. It aims to improve your health and wellbeing while you wait for your operation.
SheffieldAges 18 years+ - NCT07453004RecruitingPhase 2
Study of plonmarlimab for frequent gout attacks
This trial tests a new investigational drug called plonmarlimab for people with frequent, painful gout flares who cannot take standard treatments. The goal is to see if it can reduce pain and inflammation from the flare.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06456489RecruitingPhase 3
Pulse steroids for hard-to-treat rheumatoid arthritis
This trial tests whether a high-dose steroid injection can help people with rheumatoid arthritis that hasn't improved with other treatments. If you have RA that's not well controlled, this may be an option for you.
CairoAges 20–65 - NCT04876781Recruiting
Track safety of Xeljanz XR in Korea
This study collects real-world safety information about Xeljanz XR after it has been approved. It includes people with certain immune-related joint diseases and checks for side effects in everyday use.
SeoulAges 18 years+ - NCT07745426RecruitingPhase 2
Comparing add-on treatments for rheumatoid arthritis
This trial compares two additional medicines (diosmin or rebamipide) taken with standard arthritis treatment to see if they help reduce joint pain and swelling better than standard treatment alone.
TantaAges 18–70 - NCT06654882RecruitingPhase 3
Switching medications after first treatment fails in juvenile arthritis
This study tests different medication sequences for children and teens with polyarticular juvenile idiopathic arthritis (JIA) who still have moderate or high disease activity after at least 3 months on their first tumor necrosis factor inhibitor (TNFi) therapy. The goal is to find the best next step to control symptoms and improve quality of life.
San Francisco, CaliforniaAges 2–17 - NCT07286058RecruitingPhase 3
Long-term study of zasocitinib for psoriatic arthritis
This study is for people with psoriatic arthritis who have already completed a year-long treatment with zasocitinib or a similar medicine in a previous study. It tests whether continuing to take zasocitinib remains safe and helpful over a longer time.
Fountain Valley, CaliforniaAges 18 years+ - NCT07321873RecruitingPhase 2
Study of JNJ-88545223 for Active Psoriatic Arthritis
This study tests an experimental drug called JNJ-88545223 to see if it can reduce joint pain, swelling, and skin plaques in people with active psoriatic arthritis. It may help if you have both joint symptoms and psoriasis.
Searcy, ArkansasAges 18 years+ - NCT06807424RecruitingPhase 3
Study of icotrokinra for active psoriatic arthritis
This trial tests a new medication called icotrokinra for people with active psoriatic arthritis (PsA). It aims to see how well the drug works and if it is safe, including for those who have tried other treatments.
Glendale, ArizonaAges 18 years+ - NCT06663332RecruitingPhase 3
Long-term study of guselkumab in children who previously took it
This study is a long-term follow-up for children who have already finished an earlier study of guselkumab, a medicine for skin conditions like psoriasis. It looks at whether staying on the medicine continues to be safe and helpful over time.
Atlanta, GeorgiaAges 3 years+ - NCT07363590RecruitingPhase 1
Study of MK-1045 for lupus or rheumatoid arthritis
This study tests a new drug, MK-1045, for people with lupus or rheumatoid arthritis. It aims to see if the drug is safe and how it affects your condition.
Southport, QueenslandAges 18–75 - NCT07141004RecruitingPhase 4
Study of guselkumab for psoriatic arthritis in Indian patients
This trial tests if guselkumab, a drug given as an injection under the skin, can help people with psoriatic arthritis (PsA) who haven't had enough relief from standard treatments. It aims to find a new option for managing joint pain and swelling.
AhmedabadAges 18 years+ - NCT06100744RecruitingPhase 3
Comparing two drugs for children with psoriatic arthritis
This study tests two drugs—risankizumab and adalimumab—to see which is safer and works better for children with active psoriatic arthritis. It's for kids who have not been helped enough by standard disease-modifying drugs.
Little Rock, ArkansasAges 5–17 - NCT03704766Recruiting
Testing fluid markers to detect pediatric joint infections
This study checks special lab markers in joint fluid to tell septic (infected) arthritis apart from other inflammatory causes in children. It may help clinicians detect infection more accurately and quickly so kids can get the right treatment.
Atlanta, GeorgiaAges Up to 17 years - NCT06671496RecruitingPhase 3
Zasocitinib for psoriatic arthritis in adults
This study tests an oral medicine called zasocitinib for people with psoriatic arthritis who have not had enough relief from other treatments. It may help reduce joint pain and skin symptoms.
Mesa, ArizonaAges 18 years+
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Common questions
- Are there clinical trials for arthritis?
- Yes. Clin2 currently lists 550 recruiting arthritis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a arthritis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a arthritis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.