Clinical trials
Arthritis clinical trials
Below are recruiting arthritis clinical trials, each written for real people, not researchers. We’re tracking 553 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06301373Recruiting
Combining methotrexate and tofacitinib for rheumatoid arthritis
This study tests whether combining two medicines—methotrexate and tofacitinib—works better for people with a specific type of rheumatoid arthritis. It may be a good fit if you have moderate to severe arthritis, have had a joint biopsy that shows a certain cell pattern, and haven't used similar treatments before.
Foshan, GuangdongAges 18–65 - NCT06382051Recruiting
Improving Psoriatic Arthritis Screening in Psoriasis
This study tests a new way to screen for psoriatic arthritis (a type of joint inflammation) in people with psoriasis. It looks at a tool called PEST and aims to improve early detection.
Calgary, AlbertaAges 18 years+ - NCT06972446RecruitingPhase 2
Study of targeted therapies for rheumatoid arthritis
This trial tests different targeted treatments for people with rheumatoid arthritis who have tried one or two biologic or targeted synthetic drugs but still have symptoms. You need to be taking a stable dose of methotrexate.
Peoria, ArizonaAges 18 years+ - NCT07553273Recruiting
Vibration to reduce pain from steroid hand and arm injections
This study tests whether applying gentle vibration during steroid injections into the hands, wrists, or elbows can reduce injection pain. If vibration works, it could make these commonly prescribed treatments more comfortable for patients.
Galveston, TexasAges 18 years+ - NCT06337786Recruiting
RheumaBuddy app study for rheumatoid arthritis
This study tests if a digital app called RheumaBuddy4.1 can help manage rheumatoid arthritis symptoms. You would use the app at home and report how you feel.
Frederiksberg, Copenhagen FAges 18–65 - NCT06339957Recruiting
Rheumatology diet study for arthritis and related conditions
This study looks at how diet affects people with different types of arthritis and related autoimmune conditions. If you are a UCF Health patient between 18 and 65, you may be able to help researchers learn more about which foods help or worsen symptoms.
Orlando, FloridaAges 18–65 - NCT06383585Recruiting
Using 3D AI to detect bone changes in arthritis
This study uses a 3D artificial intelligence (AI) tool to analyze hand X-rays and MRIs for bone damage from inflammatory arthritis. It may help doctors better detect early changes and guide treatment.
Rochester, MinnesotaAges 18 years+ - NCT06417138Recruiting
Comparing rheumatoid arthritis treatments in Saudi Arabia
This study compares different drugs used to treat rheumatoid arthritis in Saudi Arabia. If you have rheumatoid arthritis and have been treated for at least a year, this study may help doctors learn which medicines work best.
Jeddah, Mecca RegionAges 18 years+ - NCT06459453Recruiting
Comparing two hand therapy techniques for rheumatoid arthritis
This study compares two gentle hand and wrist therapy techniques (Kaltenborn and Mulligan) to see which works better for people with rheumatoid arthritis. If you have limited wrist movement due to RA, you may be able to join.
Lahore, Punjab ProvinceAges 18–65 - NCT06463379RecruitingPhase 3
Intravenous pulse therapy for tough juvenile arthritis
This trial tests whether a type of intravenous medicine (called pulse therapy) can help children with arthritis that hasn't improved after other treatments. It aims to bring the disease into remission.
CairoAges 2–18 - NCT03192267Recruiting
Study of lung changes in early rheumatoid arthritis
This study looks at lung health in people with early rheumatoid arthritis (RA). It may help doctors understand how RA affects the lungs soon after diagnosis and guide better care.
Omaha, NebraskaAges 19–90 - NCT06492200Recruiting
High-Fiber Diet for Rheumatoid Arthritis
This study tests whether eating more high-fiber foods can improve rheumatoid arthritis symptoms by changing the bacteria in your gut. You would follow a special diet and have your disease activity monitored.
WürzburgAges 18–99 - NCT06503237Recruiting
SWK002 for tough-to-treat rheumatoid arthritis
This trial tests a new treatment called SWK002 for people with rheumatoid arthritis that hasn't improved after trying multiple medications. It aims to see if SWK002 can help when other treatments have failed.
Changsha, HunanAges 18 years+ - NCT06527534RecruitingPhase 4
Filgotinib vs adalimumab for rheumatoid arthritis
This study compares two RA medications, filgotinib and adalimumab, to see how they affect your body's proteins and genetic signals. It may help your doctor know which treatment is better for your type of RA.
VeronaAges 18–65 - NCT06527547Recruiting
Ear acupuncture for sleep problems in rheumatoid arthritis
This trial tests if a gentle, non-invasive ear acupuncture device can improve sleep in people with rheumatoid arthritis (RA). If you have RA, poor sleep, and your disease is under control, this study might be a good fit.
Beijing, Beijing MunicipalityAges 18–72 - NCT06544343Recruiting
Remote monitoring for new immunosuppressive therapy
This trial tests whether regular remote check-ins can help manage chronic immunosuppressive medications. If you have an autoimmune condition like rheumatoid arthritis or lupus and are starting a new medicine such as methotrexate or a biologic, you may be eligible.
Perugia, PGAges Any age - NCT06560606Recruiting
Personalized medicine for childhood arthritis
This study creates a personalized medicine network to better understand and treat childhood arthritis. If you have JIA or unexplained joint inflammation, researchers will look at your biology to find the best treatment approach for you.
Calgary, AlbertaAges Up to 18 years - NCT06572696Recruiting
Shoulder Ultrasound in Rheumatoid Arthritis Without Pain
This study uses ultrasound to look for hidden shoulder problems in people with rheumatoid arthritis who have no shoulder pain. It aims to find early changes that might need treatment before pain starts.
IstanbulAges 18–75 - NCT06596772RecruitingPhase 3
Comparing a biosimilar to Enbrel for rheumatoid arthritis
This trial tests if a new biosimilar called MB04 works as well as the standard drug Enbrel for people with moderate to severe rheumatoid arthritis. Participants will keep taking methotrexate while being assigned to one of the two drugs to see how they compare.
HaskovoAges 18–75 - NCT01422694Recruiting
Understanding spondyloarthritis over time
This study follows people with spondyloarthritis (an inflammatory arthritis that often affects the spine and joints) and their family members over time to better understand how the disease develops and progresses. It also includes a research stool sample test to learn about gut bacteria.
Bethesda, MarylandAges 2–99 - NCT06613490RecruitingEarly Phase 1
CAR NK cells for antibody syndrome and rheumatoid arthritis
This early-phase trial tests whether a new type of immune cell (CAR NK) can treat two conditions: antisynthetase antibody syndrome (a rare autoimmune disease) and rheumatoid arthritis. It's for people whose current treatments haven't worked well enough.
Nanjing, JiangsuAges 18–70 - NCT06631638Recruiting
New hip replacement study using smart navigation
This study tests a hip replacement system that uses a special navigation tool to help the surgeon place the new hip cup more precisely. It may lead to better long-term results and fewer complications.
Sacramento, CaliforniaAges 21 years+ - NCT06640309RecruitingPhase 2
Nicotinamide for rheumatoid arthritis: a clinical trial
This trial tests if taking a vitamin B3 supplement (nicotinamide) can improve outcomes for people with rheumatoid arthritis. Researchers want to see if adding this over-the-counter vitamin to your usual arthritis medicines helps reduce disease activity.
CairoAges 18–65 - NCT06649136RecruitingPhase 4
Maximizing methotrexate therapy for active rheumatoid arthritis
This trial tests whether increasing your methotrexate dose or switching from pills to injections can better control active rheumatoid arthritis. It's for people already taking a stable, moderate dose of methotrexate but still having joint swelling and symptoms.
Vienna, State of ViennaAges 18–99
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Common questions
- Are there clinical trials for arthritis?
- Yes. Clin2 currently lists 553 recruiting arthritis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a arthritis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a arthritis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.