Clinical trials · Raleigh–Durham, NC
Asthma clinical trials in Raleigh–Durham
We’re tracking 15 recruiting asthma studies with a site in or near Raleigh–Durham — including Phase 2, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies near Raleigh–Durham
- NCT00341237Recruiting
Study linking genes and environment to health risks
This study looks at how your genes and your environment may affect your health. It may help researchers better understand who is most at risk so future prevention and care can be more personalized.
Research Triangle Park, North CarolinaAges 18–120 - NCT02327897Recruiting
Study of asthma symptoms and air exposures over time
This study follows people with moderate-to-severe asthma and repeatedly checks how their lungs and symptoms relate to environmental exposures over time. It may help researchers better understand what triggers asthma and how exposures affect asthma control.
Research Triangle Park, North CarolinaAges 18–60 - NCT01143480Recruiting
Testing how the body responds to endotoxin
This study checks how your immune system (your body’s defense system) reacts to a controlled substance that triggers inflammation. It may help researchers understand why some people have stronger or weaker inflammatory responses.
Research Triangle Park, North CarolinaAges 18–100 - NCT06664619RecruitingPhase 3
Study of a new combination inhaler for asthma
This study tests a new combination inhaler (fluticasone propionate and albuterol) for people with asthma age 12 and older. It helps see if this inhaler works better than a placebo in controlling asthma symptoms and preventing attacks.
Raleigh, North CarolinaAges 12 years+ - NCT05945355Recruiting
Study of breathing training for children with asthma
This study looks at how an asthma-specific breathing training program affects children’s breathing and asthma control. It may help your care team understand who could benefit from inspiratory (breathing-in) training.
Durham, North CarolinaAges 6–17 - NCT07323654RecruitingPhase 2
Oral KT-621 for moderate to severe eosinophilic asthma
This trial tests an oral medication called KT-621 for people with moderate to severe eosinophilic asthma. It aims to see if the drug can help control asthma better than the standard inhaled treatments alone.
Durham, North CarolinaAges 18–75 - NCT07444567RecruitingPhase 3
Continuing benralizumab treatment after a previous study
This trial lets people who completed an earlier benralizumab study and are benefiting from the medicine keep receiving it. The goal is to provide ongoing access while we continue to monitor safety and effectiveness.
Durham, North CarolinaAges 6 years+ - NCT07139899Recruiting
Mucus Plugs and Lung MRI in Severe Asthma
This study is looking at how mucus plugs in the airways affect lung function in people with severe asthma. If you are about to start a new injectable asthma treatment (dupilumab, tezepelumab, or benralizumab), you may be able to join and get a special type of lung MRI to see how your lungs are doing.
Durham, North CarolinaAges 18–65 - NCT06307665RecruitingPhase 3
Asthma study for teens comparing two inhalers
This study tests a new inhaler (PT027) against another inhaler (PT007) for teens aged 12 to 17 with asthma. It looks at how well the new inhaler works when used as needed, and if it is safe.
Durham, North CarolinaAges 12–17 - NCT05608668Recruiting
Breathing and activity coaching for kids with obesity and mild asthma
This trial tests an “inspiratory pulmonary rehabilitation” program—guided breathing and exercise training—for children who have obesity and mild asthma. It may help improve breathing control and exercise ability by teaching safe, structured breathing and activity habits.
Durham, North CarolinaAges 8–17 - NCT03885245RecruitingPhase 2
L-citrulline supplement for overweight adults with later-onset asthma
This Phase 2 trial tests whether adding L-citrulline can improve asthma control in overweight adults whose asthma started later in life. It compares your asthma symptoms and lung testing results to see if the supplement helps when asthma is already being treated.
Durham, North CarolinaAges 18–65 - NCT04278404Recruiting
Drug safety study for children already on certain medicines
This study measures how certain medicines move through the body and checks their safety in children. It may help doctors better understand dosing and side effects in kids who are already receiving these treatments, or in some kids who recently tested positive for COVID-19.
Durham, North CarolinaAges birth–20 years - NCT06191315Enrolling by invitationPhase 3
Dupilumab for asthma and wheezing in young children
This study tests if the medicine Dupilumab can help control asthma and wheezing in children ages 2 to just under 6. It is for children whose symptoms are not well-managed with their current inhaler.
Chapel Hill, North CarolinaAges 2–5 - NCT06023589RecruitingPhase 3
Testing tezepelumab for kids with severe asthma
This study tests if tezepelumab can help reduce severe asthma attacks in children ages 5 to 11. It compares the drug to a placebo (a dummy treatment) to see if it is safe and effective.
Chapel Hill, North CarolinaAges 5–11 - NCT07052942RecruitingPhase 4
Asthma treatment personalization in primary care
This study tests whether adding a long-term, low-dose antibiotic (azithromycin) to your usual asthma treatment can help improve control and reduce attacks. It is for people whose asthma is still not well controlled despite using a daily inhaler.
Chapel Hill, North CarolinaAges 13–75
Hear when a new Asthma trial opens near Raleigh–Durham, NC
We’ll email you when one opens near Raleigh–Durham, NC — at most once a week, no account needed, unsubscribe anytime.
Asthma trials in other cities
Where these studies are running near Raleigh–Durham
Institutions with a site for the recruiting asthma studies listed above.
- National Institute of Environmental Health Sciences Clinical Research Unit · 3 studies
- Research Site · 3 studies
- University of North Carolina at Chapel Hill · 3 studies
- Duke Healthy Lifestyles Clinic · 2 studies
- Duke University Medical Center · 2 studies
- Duke Health Center Creekstone
- Duke University Health System
- Kymera Investigative Site
What taking part in a asthma study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Looking wider? See all recruiting asthma studies in North Carolina.
Common questions
- Are there asthma clinical trials near Raleigh–Durham?
- Yes. We're currently tracking 15 recruiting asthma studies with a site near Raleigh–Durham, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a asthma study near Raleigh–Durham?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Raleigh–Durham to take part?
- Not necessarily. These studies have a site near Raleigh–Durham, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a asthma trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New asthma studies open near Raleigh–Durham regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.