Clinical trials · North Carolina
Asthma clinical trials in North Carolina
We’re tracking 22 recruiting asthma studies with a site in North Carolina — including Phase 2, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in North Carolina
- NCT07052942RecruitingPhase 4
Asthma treatment personalization in primary care
This study tests whether adding a long-term, low-dose antibiotic (azithromycin) to your usual asthma treatment can help improve control and reduce attacks. It is for people whose asthma is still not well controlled despite using a daily inhaler.
Chapel Hill, North CarolinaAges 13–75 - NCT05945355Recruiting
Study of breathing training for children with asthma
This study looks at how an asthma-specific breathing training program affects children’s breathing and asthma control. It may help your care team understand who could benefit from inspiratory (breathing-in) training.
Durham, North CarolinaAges 6–17 - NCT07228026Recruiting
Device to Monitor Asthma by Measuring Nitric Oxide in Breath
This trial tests a handheld device that measures nitric oxide in your breath to see if it can help monitor asthma. You may qualify if you have uncontrolled asthma and can use the device at home.
Asheville, North CarolinaAges 5–100 - NCT07276724RecruitingPhase 3
Study of GB-0895 for severe uncontrolled asthma
This trial tests an add-on medicine called GB-0895 for people with severe asthma that is not well controlled with current treatments. It aims to see if adding this drug can reduce asthma attacks and improve breathing.
Gastonia, North CarolinaAges 12–80 - NCT06023589RecruitingPhase 3
Testing tezepelumab for kids with severe asthma
This study tests if tezepelumab can help reduce severe asthma attacks in children ages 5 to 11. It compares the drug to a placebo (a dummy treatment) to see if it is safe and effective.
Chapel Hill, North CarolinaAges 5–11 - NCT07323654RecruitingPhase 2
Oral KT-621 for moderate to severe eosinophilic asthma
This trial tests an oral medication called KT-621 for people with moderate to severe eosinophilic asthma. It aims to see if the drug can help control asthma better than the standard inhaled treatments alone.
Chapel Hill, North CarolinaAges 18–75 - NCT07556159Recruiting
Asthma Disease Patterns and Outcomes in Everyday Care
This study observes how asthma is managed and controlled in routine clinical practice. Researchers will collect information about your asthma symptoms, treatments, and outcomes over time to better understand real-world asthma management.
Asheville, North CarolinaAges 6 years+ - NCT06307665RecruitingPhase 3
Asthma study for teens comparing two inhalers
This study tests a new inhaler (PT027) against another inhaler (PT007) for teens aged 12 to 17 with asthma. It looks at how well the new inhaler works when used as needed, and if it is safe.
Charlotte, North CarolinaAges 12–17 - NCT06191315Enrolling by invitationPhase 3
Dupilumab for asthma and wheezing in young children
This study tests if the medicine Dupilumab can help control asthma and wheezing in children ages 2 to just under 6. It is for children whose symptoms are not well-managed with their current inhaler.
Chapel Hill, North CarolinaAges 2–5 - NCT07532265RecruitingPhase 2
Testing a New Drug for Hard-to-Control Asthma
This study tests whether a new drug called frevecitinib can help people with severe asthma that isn't well controlled even with strong inhaled steroid medications. The goal is to see if it reduces asthma attacks and improves breathing.
Charlotte, North CarolinaAges 18–75 - NCT06932263RecruitingPhase 2
Testing tozorakimab for uncontrolled asthma
This trial tests a new drug called tozorakimab for adults whose asthma is not well controlled despite using medium-to-high dose inhaled steroids. The study aims to find the best dose and see if it reduces asthma attacks.
Asheville, North CarolinaAges 18–75 - NCT03885245RecruitingPhase 2
L-citrulline supplement for overweight adults with later-onset asthma
This Phase 2 trial tests whether adding L-citrulline can improve asthma control in overweight adults whose asthma started later in life. It compares your asthma symptoms and lung testing results to see if the supplement helps when asthma is already being treated.
Durham, North CarolinaAges 18–65 - NCT05608668Recruiting
Breathing and activity coaching for kids with obesity and mild asthma
This trial tests an “inspiratory pulmonary rehabilitation” program—guided breathing and exercise training—for children who have obesity and mild asthma. It may help improve breathing control and exercise ability by teaching safe, structured breathing and activity habits.
Durham, North CarolinaAges 8–17 - NCT06664619RecruitingPhase 3
Study of a new combination inhaler for asthma
This study tests a new combination inhaler (fluticasone propionate and albuterol) for people with asthma age 12 and older. It helps see if this inhaler works better than a placebo in controlling asthma symptoms and preventing attacks.
Charlotte, North CarolinaAges 12 years+ - NCT06977581RecruitingPhase 2
study of PF-07275315 for moderate-to-severe asthma
This study tests a new medicine called PF-07275315 for people with moderate-to-severe asthma that is not well controlled with their current inhalers. It is for adults who have had asthma for at least a year, have had recent flare-ups needing steroids, and are not taking other biologic treatments.
Charlotte, North CarolinaAges 18–70 - NCT07139899Recruiting
Mucus Plugs and Lung MRI in Severe Asthma
This study is looking at how mucus plugs in the airways affect lung function in people with severe asthma. If you are about to start a new injectable asthma treatment (dupilumab, tezepelumab, or benralizumab), you may be able to join and get a special type of lung MRI to see how your lungs are doing.
Durham, North CarolinaAges 18–65 - NCT02327897Recruiting
Study of asthma symptoms and air exposures over time
This study follows people with moderate-to-severe asthma and repeatedly checks how their lungs and symptoms relate to environmental exposures over time. It may help researchers better understand what triggers asthma and how exposures affect asthma control.
Research Triangle Park, North CarolinaAges 18–60 - NCT06609239Enrolling by invitationPhase 2
Long-term safety study of Lunsekimig for asthma
This trial tests the long-term safety and effectiveness of Lunsekimig, an investigational drug, for adults with asthma. It is for people who have already completed a previous Lunsekimig study and are on stable asthma medications.
Charlotte, North CarolinaAges 18 years+ - NCT04278404Recruiting
Drug safety study for children already on certain medicines
This study measures how certain medicines move through the body and checks their safety in children. It may help doctors better understand dosing and side effects in kids who are already receiving these treatments, or in some kids who recently tested positive for COVID-19.
Chapel Hill, North CarolinaAges birth–20 years - NCT07444567RecruitingPhase 3
Continuing benralizumab treatment after a previous study
This trial lets people who completed an earlier benralizumab study and are benefiting from the medicine keep receiving it. The goal is to provide ongoing access while we continue to monitor safety and effectiveness.
Durham, North CarolinaAges 6 years+ - NCT00341237Recruiting
Study linking genes and environment to health risks
This study looks at how your genes and your environment may affect your health. It may help researchers better understand who is most at risk so future prevention and care can be more personalized.
Chapel Hill, North CarolinaAges 18–120 - NCT01143480Recruiting
Testing how the body responds to endotoxin
This study checks how your immune system (your body’s defense system) reacts to a controlled substance that triggers inflammation. It may help researchers understand why some people have stronger or weaker inflammatory responses.
Research Triangle Park, North CarolinaAges 18–100
Asthma trials by city in North Carolina
Where these studies are running in North Carolina
Institutions with a site for the recruiting asthma studies listed above.
- Research Site · 6 studies
- National Institute of Environmental Health Sciences Clinical Research Unit · 3 studies
- University of North Carolina at Chapel Hill · 3 studies
- Allergy Partners · 2 studies
- Duke Healthy Lifestyles Clinic · 2 studies
- Duke University Medical Center · 2 studies
- American Health Research
- Atrium Health
What taking part in a asthma study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Asthma trials in other states
Common questions
- Are there asthma clinical trials in North Carolina?
- Yes. We're currently tracking 22 recruiting asthma studies with a site in North Carolina, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a asthma study in North Carolina?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in North Carolina to take part?
- Not necessarily. These studies have a site in North Carolina, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a asthma trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New asthma studies open in North Carolina regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.