Clinical trials · Texas
Bipolar II Disorder clinical trials in Texas
We’re tracking 16 recruiting bipolar ii disorder studies with a site in Texas — including Phase 1, Phase 2 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies in Texas
- NCT07220460RecruitingPhase 2
Study of an oral drug for bipolar depression
This trial tests an experimental pill (ABB-932) for people with bipolar I or II disorder who are currently in a depressive episode. The goal is to see if the drug is safe and helps improve mood.
The Woodlands, TexasAges 18–65 - NCT06656416RecruitingPhase 2
ALTO-100 for bipolar depression
This trial tests an investigational drug called ALTO-100 in people with bipolar I or II who are currently experiencing depression. It looks at whether this new medicine can help improve depression symptoms when taken alongside your usual mood stabilizer or antipsychotic medication.
Houston, TexasAges 18–70 - NCT06706232RecruitingPhase 2
Psilocybin for Depression and Suicidal Thoughts in Bipolar II
This trial tests if two doses of psilocybin, given under medical supervision, are safe and acceptable for people with Bipolar II disorder who have mild to moderate depression and certain suicidal thoughts. The goal is to see if it may help improve mood and reduce suicidal thinking.
Houston, TexasAges 25–70 - NCT05025605RecruitingPhase 1
Study medicine for agitation in youth with bipolar or schizophrenia
This Phase 1 trial tests whether BXCL501 is safe and can help reduce agitation in children and teens who have bipolar disorder or schizophrenia. You may be considered if your agitation is significant during screening, but certain recent medication and health factors can make you ineligible.
DeSoto, TexasAges 10–17 - NCT06229210RecruitingPhase 3
Lumateperone safety study for children with schizophrenia, bipolar, or autism
This trial tests a medication called lumateperone for children and teens with schizophrenia, bipolar disorder, or autism spectrum disorder. It aims to see if the medicine is safe and tolerable over time.
Coppell, TexasAges 5–17 - NCT06696755RecruitingPhase 2
Study of icalcaprant for bipolar depression
This study tests an oral medication called icalcaprant for adults with bipolar I or II who are currently in a depressive episode. The goal is to see if it reduces symptoms and whether it's safe when taken alongside your usual mood stabilizer.
Austin, TexasAges 18–65 - NCT07172516RecruitingPhase 3
Study of azetukalner vs placebo for bipolar depression
This trial tests whether the study drug azetukalner can help reduce depression symptoms in people with bipolar I or II disorder who are currently having a depressive episode. You would be randomly assigned to receive either the drug or a placebo (inactive pill) to see which works better.
Atascocita, TexasAges 18–74 - NCT07286175RecruitingPhase 2
Study of brenipatide for bipolar disorder
This trial tests an experimental drug called brenipatide for people with bipolar I or II disorder. It aims to see if the drug can help manage mood episodes when added to your current stable medications.
McKinney, TexasAges 18–75 - NCT07622927Recruiting
Family conversations about bipolar disorder risk in youth
This study helps families talk about bipolar disorder when a parent or caregiver has it. Researchers are creating and testing a new tool to help young people understand their risk and recognize early warning signs, with the goal of getting help sooner if needed.
Dallas, TexasAges 7 years+ - NCT07217860Enrolling by invitationPhase 3
Long-term safety study of azetukalner for bipolar depression
This study is looking at the long-term safety of azetukalner for people with bipolar I or II depression who have already completed a previous trial of this drug. It is an open-label study, meaning everyone will receive the active medication.
Wichita Falls, TexasAges 18–75 - NCT06951698RecruitingPhase 3
Testing KarXT for bipolar I mania
This trial tests a new medicine, KarXT, to see if it can safely treat manic episodes in people with bipolar I disorder. It is for patients who are currently hospitalized for a manic episode that started within the last 3 weeks.
Irving, TexasAges 18–65 - NCT06929273RecruitingPhase 3
Long-term safety study of KarXT for bipolar I mania
This study tests the long-term safety of KarXT for people with bipolar I disorder who are having a manic or mixed episode. It is for people who either completed a previous KarXT study or are new to the study and have moderate to severe mania symptoms.
Austin, TexasAges 18–65 - NCT06951711RecruitingPhase 3
KarXT for mania in bipolar I disorder
This study tests a new medication called KarXT to see if it helps calm manic episodes in people with bipolar I disorder. You would need to be in the hospital for a manic episode and stop other psychiatric medications temporarily.
DeSoto, TexasAges 18–65 - NCT07140913RecruitingPhase 3
Testing KarXT for bipolar I mania with mood stabilizers
This study tests whether adding KarXT to lithium, valproate, or lamotrigine helps calm manic episodes in people with bipolar I disorder. It aims to see if the combination is safe and works better than the mood stabilizer alone.
Houston, TexasAges 18–65 - NCT06665984Recruiting
Greater Houston pediatric bipolar registry study
This study is creating a registry to learn more about bipolar disorder in children and teens. It includes youth who have bipolar disorder and those who have a parent with bipolar disorder, as well as healthy youth for comparison.
Houston, TexasAges 6–17 - NCT04080778Recruiting
Magnetic seizure treatment for severe bipolar or hard-to-treat depression
This trial studies whether a seizure-like therapy using magnet stimulation can quickly reduce severe depressive symptoms in people with bipolar depression or treatment-resistant depression. It may help when depression is intense and hasn’t improved enough with at least two antidepressant medicines.
Houston, TexasAges 22–85
Bipolar II Disorder trials by city in Texas
Where these studies are running in Texas
Institutions with a site for the recruiting bipolar ii disorder studies listed above.
- Pillar Clinical Research · 6 studies
- Community Clinical Research · 3 studies
- The University of Texas Health Science Center at Houston · 3 studies
- Adams Clinical · 2 studies
- Elevate Clinical Research · 2 studies
- Family Psychiatry of The Woodlands · 2 studies
- Grayline Research Center · 2 studies
- Local Institution · 2 studies
What taking part in a bipolar ii disorder study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Bipolar II Disorder trials in other states
Common questions
- Are there bipolar ii disorder clinical trials in Texas?
- Yes. We're currently tracking 16 recruiting bipolar ii disorder studies with a site in Texas, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a bipolar ii disorder study in Texas?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Texas to take part?
- Not necessarily. These studies have a site in Texas, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a bipolar ii disorder trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New bipolar ii disorder studies open in Texas regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.