Blood Disease clinical trials

Essential tremor subtypes and progression markers study

This study looks for biological markers to better understand different types of essential tremor and how the condition changes over time. It may help identify who has which subtype and predict disease progression.

Study unusual heart conditions and related genetic traits

This study looks at people with unusual or rare heart problems, or people with a family history of these issues. Doctors and researchers may collect and study your blood or tissue (and possibly store samples) to learn what causes the condition and how it may affect the heart.

Finding early signs of Parkinson's and related diseases

This study looks at cells from the nose, blood, and urine to find early markers for Parkinson's disease, similar conditions, and memory problems linked to Lewy bodies. If you have one of these conditions, joining could help improve early diagnosis.

Online tests to spot early Alzheimer’s changes

This study looks at whether online motor (movement) and thinking tasks can detect early changes related to Alzheimer’s disease. You may be able to take part if you’re over 50 and do not already have a diagnosis of dementia.

Donating breath, blood, and urine samples for lung research

This study collects airway samples (usually during a bronchoscopy), plus blood and/or urine, to help researchers study lung conditions. It may help advance understanding of lung disease and related biology, but it is not a treatment trial.

Opening the blood-brain barrier for ALS treatment

This trial tests a device that temporarily opens the barrier between the blood and brain to see if it can help slow down ALS. It may allow treatments to reach the brain more effectively.

MRI test of eye blood flow in specific optic nerve conditions

This study uses a special MRI scan to measure blood flow to the eye and check how consistently the results match over time. It may help doctors better assess certain optic nerve problems, especially in people without major cardiovascular risk factors.

Kidney & blood pressure in childhood cancer survivors

This study looks at kidney health and blood pressure in childhood cancer survivors. If you finished high-risk cancer therapy about 3 years ago, researchers want to see how your kidneys and blood pressure are doing now.

Alzheimer's assessment study with brain scans

This study uses brain scans (MRI and EEG) to better understand Alzheimer's disease. It compares people with MCI or Alzheimer's to healthy volunteers to see how the disease affects the brain.

Blood study on sleep loss

This study looks at blood samples to understand how sleep loss affects the body. It may help find new ways to diagnose or treat sleep problems.

Understanding new blood markers in memory loss and dementia

This study is looking for older adults (60+) to help researchers better understand how to detect and track memory changes and dementia. Participants will provide blood samples and other health information over time to identify new markers that might help with early diagnosis.

Skin biomarkers for inflammatory disease treatment

This study looks for clues in your skin and blood that could predict how well you'll respond to treatments for conditions like eczema, psoriasis, or lupus. It aims to help doctors choose the best therapy for you.

Hairy cell leukemia disease burden study

This study watches the course of hairy cell leukemia (HCL) in different phases—when first diagnosed, after it comes back, or long after successful treatment. The goal is to better understand the disease and plan future care.

Testing a new GVHD prevention method after donor stem cell transplant

This trial tests a new way to prevent graft-versus-host disease (a common side effect of stem cell transplant) using a drug called cyclophosphamide after transplant. It is for adults with certain blood cancers who need a transplant from a partially matched unrelated donor.

How insomnia affects DNA, heart health, and lifestyle

This study looks at how insomnia affects your DNA, heart health, metabolism, and daily habits. It includes different groups of people—healthy adults, athletes, older adults, university students, and people with metabolic syndrome—to compare the impact of sleep problems.

Autoimmune antibodies before immunotherapy

This study is looking for people about to start immune checkpoint inhibitor therapy to see if certain antibodies are present. It may help understand how the body reacts to this treatment.

Chronic wounds and blood circulation checkup

This study checks how well blood flows in the legs of people with and without chronic wounds or circulation problems. It may help doctors better understand and treat poor circulation.

Esophageal risk and tissue registry study

This study collects information and, if you already need blood tests or procedures, may take extra small tissue samples (biopsies) to better understand esophageal-related conditions. It may help researchers learn about risk and future management for people with certain esophagus or reflux-related diagnoses.

Blood tests for brain diseases and mental health conditions

This study looks at blood tests to help diagnose and track brain diseases (like Alzheimer's) or mental health conditions. It compares patients to healthy volunteers to find better ways to detect and monitor these illnesses.

Study of the Disease Process of Lymphangioleiomyomatosis

Pregnant people with or without antiphospholipid antibodies

This study is looking at pregnancy outcomes in people who are pregnant and either have antiphospholipid antibody syndrome (APS) or do not have APS but do have prior full-term pregnancies. It may help doctors understand risks and how to manage pregnancies in these groups.

Study blood and tissue samples for vascular disease discovery

This study collects blood (and sometimes tissue samples) from people who may have vascular (blood vessel) problems and from certain pregnant participants. Researchers use the samples to better understand vascular disease and to help guide future research.

Using a finger sensor to predict low blood pressure during dialysis

This trial tests if a non-invasive finger sensor (PVI) can predict when blood pressure drops during dialysis. If successful, it could help prevent dangerous low blood pressure episodes.

Beetroot powder for blood pressure in men with hypertension

This trial tests whether taking 20 grams of beetroot powder daily can help lower blood pressure and improve blood flow in men who already have high blood pressure under control with medication. Beetroot is rich in nitrates, which may relax blood vessels.