Clinical trials
Bone Tumor clinical trials
Below are recruiting bone tumor clinical trials, each written for real people, not researchers. We’re tracking 60 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07112989Recruiting
Building lab models for sarcoma and cancer spread
This study aims to create new laboratory models to better understand sarcomas and cancers that have spread to the bone or lungs. By using donated tumor tissue and blood, researchers hope to learn how these cancers grow and develop, which could lead to better treatments in the future.
BolognaAges Up to 85 years - NCT06881498Recruiting
Blood thinning technique for bone tumor surgery
This trial tests a technique called 'acute normovolemic hemodilution' during bone tumor surgery. It involves temporarily thinning your blood by removing some red blood cells and replacing them with fluid, which may reduce the need for blood transfusions.
Hangzhou, ZhejiangAges 18–75 - NCT06486506Recruiting
Results of thigh bone replacement after bone tumor surgery
This study looks back at patients who had surgery to replace the top part of the thigh bone after a bone sarcoma. Researchers want to understand how well these surgeries worked over time.
Bologna, BOAges 18–90 - NCT07197645RecruitingPhase 1
Samarium for pain from bone cancer
This trial tests a new radioactive drug (samarium) given once to reduce severe bone pain from cancer that has spread to the bones. It is for people whose pain is not controlled by current treatments and who cannot have standard radiation.
Miami, FloridaAges 18 years+ - NCT03295981RecruitingPhase 3
Bisphosphonate treatment to prevent giant cell tumor return
This study looks at whether taking a bone-strengthening medicine called a bisphosphonate after surgery can lower the chance that a giant cell tumor in a leg or arm comes back. It may help prevent recurrence after removing the tumor from the bone.
Los Angeles, CaliforniaAges 18 years+ - NCT07609277Recruiting
Blood test to track giant cell bone tumors
This study uses a simple blood test (TRACP-5b) to help diagnose and monitor giant cell tumors of the bone. Researchers want to see if this test can better track how the tumor responds to treatment or comes back over time.
BrnoAges 18 years+ - NCT06459141Recruiting
Blood Thinning During Bone Tumor Surgery
This study tests whether a technique that thins your blood during surgery can help people having bone tumor removal. It may reduce the need for blood transfusions.
Hangzhou, ZhejiangAges 18–75 - NCT07315828RecruitingPhase 4
ICG imaging to improve surgery for giant cell bone tumors
This trial uses a special dye called indocyanine green (ICG) during surgery to make giant cell bone tumors glow, helping doctors remove them more accurately. It may lead to better surgical outcomes for people with this tumor type.
ShanghaiAges 18–75 - NCT05595603RecruitingPhase 2
Zoledronic acid in bone cement after tumor scraping
This trial tests whether adding zoledronic acid (a bone-strengthening medicine) into bone cement at the surgical site can help prevent giant cell bone tumor from coming back after surgeons scrape it out from inside the bone. It is for people whose tumor can be treated with a specific “scrape-and-reconstruct” surgery and who have not had related medicines before.
HangzhouAges Any age - NCT05468970Recruiting
Study of bone and soft tissue tumors and treatment outcomes
This study looks at people with bone or soft tissue tumors to understand their features, treatments used, and survival outcomes. It may help doctors learn which care approaches work best for different tumor subtypes.
Zhengzhou, HenanAges 6–99 - NCT06165419RecruitingPhase 2
High-dose radiation for spine metastases from solid tumors
This trial tests a new way of giving high-dose radiation to solid tumors that have spread to the spine. It is for people whose spine is stable, have not had prior treatment to that area, and have only minor weakness (if any).
Stony Brook, New YorkAges 18 years+ - NCT07028268RecruitingPhase 2
Testing a new drug for bone metastases from solid tumors
This trial tests a new drug called SHR-2017 for people with solid tumors that have spread to the bones. The study aims to see if the drug can help manage pain and other effects of bone metastases.
Guangzhou, GuangdongAges 18 years+ - NCT05779670Recruiting
Check if home exercises work after leg bone tumor surgery
This trial looks at whether a personalized home exercise plan helps people recover after surgery to rebuild a lower leg for a bone tumor. It may help by improving exercise adherence using support for at-home care during treatment.
BolognaAges 12–90 - NCT06171282RecruitingEarly Phase 1
Virus therapy for advanced bone and soft tissue tumors
This trial tests an investigational virus therapy (R130) injected directly into tumors for people with advanced bone or soft tissue cancer who have exhausted standard treatments or choose not to pursue them.
ShanghaiAges 16–75 - NCT06120426Recruiting
Surgery types and radiation for spinal tumors that have spread
This study compares two types of spinal surgery combined with radiation for people whose cancer has spread to the spine in a limited way (no more than 5 spots). It aims to find which approach better controls pain, tumor growth, and spinal stability.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06647901RecruitingPhase 1/Phase 2
ICG dye imaging for giant cell tumor surgery
This trial uses a special dye (ICG) and a camera to help surgeons see the tumor better during surgery for giant cell tumors of bone in the arms or legs. The goal is to remove all of the tumor while saving as much healthy bone as possible.
Beijing, Beijing MunicipalityAges 18–65 - NCT06069570RecruitingPhase 1
Gamma delta T cells and low dose radiation for advanced lung or bone cancer
This trial tests a new type of immune cell called gamma delta T cells combined with low-dose radiation to treat people with advanced lung cancer or solid tumors that have spread to the bone. It is only for patients who have already tried standard treatments and either didn't get better or couldn't tolerate them.
Tucson, ArizonaAges 18 years+ - NCT07087197RecruitingPhase 1
Study of SKB107 for advanced cancer with bone tumors
This trial tests a new drug, SKB107, for people whose advanced cancer has spread to the bones and standard treatments no longer work. The goal is to see if SKB107 can help shrink or slow these bone tumors.
ShanghaiAges 18–75 - NCT06774729Recruiting
Predicting tumor spread using MRI in sarcoma or bone cancer
This trial uses MRI scans to create a model that may predict if a musculoskeletal tumor is spreading. It aims to help doctors decide on the best surgical treatment.
BolognaAges 18 years+ - NCT07018960Recruiting
Chest wall repair with custom 3D-printed titanium implant
This study is testing a new way to repair large chest wall defects using a custom-made 3D-printed titanium implant. It may help people who need chest wall reconstruction after cancer surgery, a bad injury, or damage from infection or radiation.
Cruces, Basque CountryAges 18 years+ - NCT07514819Recruiting
Adaptive Proton Therapy Planning for Children With Cancer
This study tests a new way to plan proton radiation therapy (a precise type of cancer treatment) for children with solid tumors or Hodgkin's lymphoma. The goal is to improve how doctors adapt treatment during therapy to better target tumors while protecting healthy tissue.
Memphis, TennesseeAges Any age - NCT06935864Recruiting
Study of KLF4 and KLF7 in bone tumors
This study looks at two proteins, KLF4 and KLF7, in bone tumor samples. It aims to understand their role in osteosarcoma and Ewing sarcoma, which may help develop better treatments.
CairoAges 1 month–39 years - NCT06401330RecruitingPhase 3
Wilms tumor treatment study for children and young adults
This study is testing different treatments for children and young adults with a type of kidney cancer called Wilms tumor. The treatment you get depends on certain risk factors, like tumor stage and lab results. The goal is to give the right amount of treatment for each person's situation.
Birmingham, AlabamaAges Up to 30 years - NCT06302465Recruiting
Narlumosbartmab plus chemo for bone cancers with giant cells
This trial tests a new drug called Narlumosbartmab added to standard chemotherapy for certain types of bone cancer that have eaten away at the bone and contain large, abnormal cells. It is for people who have not yet started standard treatment and whose tumors can be removed with surgery.
Beijing, Beijing MunicipalityAges 8 years+
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Common questions
- Are there clinical trials for bone tumor?
- Yes. Clin2 currently lists 60 recruiting bone tumor studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a bone tumor trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a bone tumor trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.