Clin2
NCT06069570Possibly a fitRecruiting

Gamma delta T cells and low dose radiation for advanced lung or bone cancer

Carcinoma, Non-Small-Cell Lung CancerBone Metastases From Solid Tumors

Part of Cancer, Lungs & breathing clinical trials.

This trial tests a new type of immune cell called gamma delta T cells combined with low-dose radiation to treat people with advanced lung cancer or solid tumors that have spread to the bone. It is only for patients who have already tried standard treatments and either didn't get better or couldn't tolerate them.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1
Enrollment
48 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are 18 years or older and weigh at least 110 pounds (50 kg).
  • You have advanced lung cancer or a solid tumor that has spread to the bone, and you have already tried chemotherapy, immunotherapy, or other standard treatments.
  • Your overall health is good enough that you are up and doing daily activities most of the time (ECOG 0 or 1).
  • You have at least one tumor that can be seen on a scan, or you have bone-only spread (no measurable tumor needed).
  • Your kidneys, liver, and blood counts are in adequate range, and you are willing to use birth control for at least 4 months after treatment.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT03356808Not yet recruiting· Phase 1/Phase 2
T cells for advanced lung cancer

This trial tests a personalized treatment using your own immune cells (T cells) that are specially trained to find and attack lung cancer cells. It may help people with advanced or relapsed lung cancer who have not improved with standard treatments.

Shenzhen, Guangdong
NCT07144735Recruiting
Gamma-delta T cell therapy for glioblastoma

This trial tests a new immune cell therapy (gamma-delta T cells from a healthy donor) for people with glioblastoma that has come back or gotten worse after standard treatment. It aims to see if these cells can help fight the tumor.

Beijing, Beijing Municipality
NCT06173219Recruiting· Phase 1/Phase 2
Radiation and immunotherapy for advanced cancer

This trial tests combining two types of radiation therapy with an immunotherapy drug for people with advanced solid tumors that have spread or come back. The goal is to see if this approach can help when standard treatments have stopped working or aren’t an option.

Beijing, Beijing Municipality
NCT06150885Recruiting· Phase 1/Phase 2
An immune cell therapy for advanced solid tumors

This trial tests a new type of immune cell therapy (CAR gamma-delta T cells) for advanced solid tumors that have not responded to standard treatments. The therapy uses donor cells that are specially trained to find and attack cancer cells.

Taichung, Non-US
NCT07467863Recruiting· Phase 1/Phase 2
Gene-modified immune cells for advanced lung cancer

This trial tests an experimental immune cell therapy (CAR-NK cells) that targets two to three specific markers on your lung cancer cells. It may be an option if your cancer has stopped responding to standard treatments and if tests show your tumor carries those markers.

Shenzhen, Guangdong
NCT07146230Not yet recruiting· Phase 2
Personalized radiation and immunotherapy for advanced lung cancer

This trial tests giving radiation and immunotherapy together to people with advanced lung cancer that hasn't been treated yet. The goal is to see if this combination can shrink tumors and help patients live longer.

The Bronx, New York

Hear when a new Carcinoma, Non-Small-Cell Lung Cancer trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.