Clinical trials
Borderline Personality Disorder clinical trials
Below are recruiting borderline personality disorder clinical trials, each written for real people, not researchers. We’re tracking 46 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06493708Recruiting
EMDR Therapy for Borderline Personality Disorder
This study tests whether Eye Movement Desensitization and Reprocessing (EMDR) therapy can help people with Borderline Personality Disorder (BPD). EMDR is a type of talk therapy often used for trauma, and this trial wants to see if it can improve BPD symptoms.
Brescia, BresciaAges 18–65 - NCT04296604Recruiting
tDCS brain stimulation to improve thinking and mood
This study tests whether a non-surgical brain stimulation called tDCS can improve “executive function,” which means skills like planning, focus, and decision-making. It is designed for people with several mental health and substance-use conditions, and it may help you if those skills are affected by your diagnosis.
Boston, MassachusettsAges 18–65 - NCT06446765RecruitingPhase 2
Mindfulness and brain feedback to boost BPD therapy
This study tests whether combining mindfulness training with brain scan feedback (neurofeedback) can improve the benefits of regular talk therapy for adults with borderline personality disorder. It takes place at Yale University.
New Haven, ConnecticutAges 18–60 - NCT06458933RecruitingPhase 2
Couples therapy for borderline personality disorder
This study tests talk therapy for couples where one person has borderline personality disorder (BPD). It aims to see if the therapy helps improve symptoms and relationship quality.
Toronto, CaliforniaAges 19 years+ - NCT03994510Recruiting
Study of shame in borderline personality disorder
This study looks at how people with borderline personality disorder experience shame and how that relates to symptoms and behavior. The goal is to better understand shame so future treatments can be more targeted.
Montpellier, HéraultAges 18 years+ - NCT05986552Enrolling by invitation
How group or individual therapy affects schema therapy for BPD
This study compares individual and group formats of schema therapy for borderline personality disorder (BPD). It aims to see which format works better for reducing symptoms and improving daily life.
AmsterdamAges 18–70 - NCT05913544Recruiting
Integrative therapy for young adults with borderline personality disorder
This trial tests a short integrative therapy program along with repeated thinking (neurocognitive) and mental health assessments for young adults with borderline personality disorder (BPD). It may help improve symptoms and cognitive functioning by combining structured therapy and targeted evaluations.
NîmesAges 16–25 - NCT05800925Recruiting
Triage survey to check who can join psychiatry research
This study uses a short questionnaire to figure out who is eligible to join future psychiatry research. It may help people get routed into studies that match their situation and safety needs.
Boston, MassachusettsAges 18 years+ - NCT05712057Recruiting
Brain stimulation vs therapy for emotion regulation problems
This trial compares a type of brain stimulation (rTMS) to therapy to help people better manage strong emotions. You may be eligible if you have ongoing difficulties with emotion control and meet specific mood, anxiety, or related symptom criteria.
Durham, North CarolinaAges 18–55 - NCT05698589Recruiting
Therapy program to reduce self-stigma in mental health
This study looks at how a program may help people with long-term mental health conditions feel less shame about their diagnosis (self-stigma). It is meant for adults who are stable enough to participate and who speak French.
BordeauxAges 18 years+ - NCT05651295Recruiting
Smartphone precision study to improve emotion regulation
This trial tests a precision approach delivered through a smartphone to better track and target how you manage strong emotions. It may help if you have ongoing difficulty regulating emotions day to day.
Columbus, OhioAges 18 years+ - NCT04870255Recruiting
Brain stimulation for depression in borderline personality disorder
This study tests a type of brain stimulation called rTMS to see if it can help improve mood in people who have both depression and borderline personality disorder. It may offer a new treatment option for those who haven't tried TMS before.
Stanford, CaliforniaAges 18–80 - NCT03846375Recruiting
Therapy trial for self-harm and suicidal thoughts
This study looks at emotional regulation during and alongside standard outpatient dialectical behavior therapy (DBT) for people who have self-harmed or had suicidal thoughts. It may help the team understand which emotions or patterns change with treatment.
BergenAges 18–65 - NCT07551882RecruitingPhase 2
Oxytocin and self-compassion training for borderline personality disorder
This study tests whether oxytocin (a hormone given as a nasal spray) combined with training in self-compassion can help people with borderline personality disorder, especially those who are very self-critical. You would receive the oxytocin spray and participate in self-compassion training sessions over several weeks.
Barcelona, BarcelonaAges 18–50 - NCT07509216Recruiting
Long-term follow-up of mentalization-based treatment after 10+ years
This long-term follow-up study looks at people who received mentalization-based treatment (a type of therapy) more than 10 years ago for a personality disorder. The goal is to learn how their lives have changed and what value the treatment may have had over time.
AmsterdamAges 18 years+ - NCT06195553Recruiting
STEPPS program for borderline personality disorder and families
This study tests a program called STEPPS to help people with borderline personality disorder (BPD) learn new skills. It also offers a program for family members to learn how to support their loved one.
Castellon, SpainAges 18 years+ - NCT07450105Enrolling by invitation
Intensive DBT for Teens Who Self-Harm or Feel Suicidal
This study tests whether an intensive type of therapy called dialectical behavior therapy (DBT) can help teenagers who are hurting themselves or feeling suicidal. It focuses on young people with signs of borderline personality disorder, and includes parents or caregivers in the treatment.
BergenAges 14–17 - NCT04318899Recruiting
Studying who benefits in a specific borderline personality therapy program
This study looks at which factors predict how people do over time and how well they respond to a therapy program for borderline personality disorder. If you have a history of repeated self-harm, your experiences may help researchers understand who is most likely to improve—and why.
Oslo, OsloAges 12–70 - NCT06626789RecruitingPhase 1/Phase 2
Brain signal training to help regulate emotions
This study tests a new brain-training technique that may help people with borderline personality disorder manage their emotions better. You will do mental exercises while an MRI scans your brain, and the results will show whether this training can reduce emotional distress.
Freiburg im BreisgauAges 18–65 - NCT06591754Enrolling by invitation
Personality disorder therapy study at Karolinska
This trial tests a special talk therapy (ISTDP) for people with personality disorders. It aims to see if the therapy helps in a psychiatric clinic setting.
StockholmAges 18 years+ - NCT06944587Recruiting
Personalized care for advanced pancreatic cancer
This trial is testing a new way to treat pancreatic cancer that has spread to nearby tissues but not to distant organs. It uses a tailored plan that may include chemotherapy and possibly surgery. The goal is to see if this personalized approach helps people live longer and better.
Bergen, NorwayAges 18 years+ - NCT05500391RecruitingPhase 2
Testing whether remote nurse monitoring works like in-person checks
This Phase 2 study compares two ways of checking your cancer follow-up: a doctor or nurse visits in person versus remote monitoring by phone and imaging. The goal is to see whether remote monitoring can safely replace or match in-person care for certain low-risk cancers and after surgery.
AmiensAges 18 years+
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Common questions
- Are there clinical trials for borderline personality disorder?
- Yes. Clin2 currently lists 46 recruiting borderline personality disorder studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a borderline personality disorder trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a borderline personality disorder trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.