Clinical trials
BOTOX clinical trials
Below are recruiting botox clinical trials, each written for real people, not researchers. We’re tracking 44 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06903975RecruitingPhase 4
Botox for a more feminine neck appearance
This trial tests Botox injections into the neck muscles to create a more feminine neck contour. It may be an option if you're looking for a non-surgical way to soften or slim the look of your neck.
Newton, MassachusettsAges 18–65 - NCT06937944RecruitingPhase 3
New Botox-like injection for frown lines
This study tests a new botulinum toxin injection (similar to Botox) to see how well it smooths moderate to severe frown lines between the eyebrows. The treatment is given as a single injection and may help soften those lines for several months.
Beijing, Beijing MunicipalityAges 18–65 - NCT07374341Recruiting
Botox for jaw fractures near the joint
This trial is testing whether guided Botox (botulinum toxin) injections into the chewing muscles can help treat certain types of jaw fractures near the joint. It may be an option if you have a mild to moderate break on one side and your bite is stable.
AlexandriaAges 18–40 - NCT07648290RecruitingEarly Phase 1
Testing a Self-Check System After Bladder Botox Treatment
This study tests a computer-based system to help you monitor your bladder symptoms after receiving Botox injections for overactive bladder or urge incontinence. The goal is to see if you can use this self-check tool at home to track how well the treatment is working.
Cleveland, OhioAges 18 years+ - NCT04630873RecruitingPhase 1
Botox dilution options for walking in hemiplegic gait
This Phase 1 study tests whether using a lower or higher dilution of Botox injections improves walking in people with hemiplegic gait. The goal is to see which dilution works better (and is safe) for walking and leg stiffness.
IoanninaAges 18 years+ - NCT04791579RecruitingPhase 2
Preventing UTIs after Botox for neurogenic bladder
This study tests whether taking an antibiotic (ciprofloxacin) around the time of bladder Botox can prevent urinary tract infections (UTIs) in people whose bladder problems are caused by nerve conditions. It may help lower the chance of infection after treatment.
Edmonton, AlbertaAges 18–100 - NCT05878951RecruitingPhase 2/Phase 3
Botox during HoLEP for men with overactive bladder symptoms
This study tests whether adding a Botox shot into the bladder during HoLEP surgery helps men with overactive bladder symptoms like urgency, frequent urination, and accidents. You’d be compared to the standard approach to see if symptoms improve after surgery.
Chicago, IllinoisAges 18–89 - NCT06216886RecruitingPhase 4
Botox injections for trigeminal neuralgia pain
This study tests Botox (onabotulinumtoxinA) injections to reduce pain attacks in people with trigeminal neuralgia who haven't gotten enough relief from medication or don't want surgery. You must have frequent attacks (more than 10 per week) and be on a stable medication dose.
Stanford, CaliforniaAges 18 years+ - NCT06387329RecruitingPhase 4
Antibiotic to prevent UTI after bladder Botox
This study tests whether taking a low-dose antibiotic (nitrofurantoin) before a Botox bladder injection can help prevent urinary tract infections. You may be able to join if you are getting Botox for overactive bladder or painful bladder syndrome and do not have frequent UTIs or other health issues that would make the antibiotic unsafe.
Bethesda, MarylandAges 18 years+ - NCT06684249Recruiting
Comparing nerve block and Botox for chronic migraine
This study compares two treatments for chronic migraine: a nerve block (injection near the nerves in the head) and Botox injections. It aims to see which one works better to reduce headache days and improve quality of life.
Zagazig, Sharqia ProvinceAges 18–65 - NCT06785844RecruitingEarly Phase 1
Botulinum toxin injection for children with hard-to-treat bowel leakage
This trial tests a one-time injection of botulinum toxin (like Botox) into the bottom muscle to help children who have frequent, stubborn bowel leakage. It aims to see if relaxing the muscle can reduce accidents.
JerusalemAges 4–18 - NCT06796985RecruitingPhase 1
Botox for Chronic Pelvic Pain in Women
This study tests whether a Botox injection into the pelvic floor muscles can reduce chronic pelvic pain. It is for women who have had pelvic pain for at least 6 months, with tender muscle knots in the pelvic area.
Miami, FloridaAges 18–75 - NCT06807164RecruitingPhase 2
Comparing three injections for nerve pain after breast cancer surgery
This trial tests three different injections (a nerve block, capsaicin, or botox) to find which works best for chronic nerve pain after breast cancer surgery. If you have ongoing pain in a small area on your chest, armpit, or arm that started 3 to 9 months after surgery, this study may help you find better relief.
Lille, Hauts-de-FranceAges 18 years+ - NCT06839118RecruitingPhase 3
Botox for headaches after head injury
This trial tests if Botox injections can reduce headache days in people with persistent headaches after a mild head injury. It may help if you have headaches at least 15 days a month.
Glostrup MunicipalityAges 18–80 - NCT06902805RecruitingPhase 2/Phase 3
Testing botox injections and splints for thumb arthritis pain
This study tests if botox injections into the thumb joint, along with a custom splint, can reduce pain from thumb base arthritis. It may be an option if you have persistent pain and have not had recent thumb surgery or certain other treatments.
Paris, Île-de-France RegionAges 18 years+ - NCT06928246RecruitingPhase 1
Botox for Eczema: A Skin & Nerve Study
This trial tests whether Botox injections can improve eczema by calming nerve-immune system interactions. It is for adults with mild-to-moderate eczema who have not used certain stronger treatments recently.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT07025642Recruiting
Overactive Bladder Treatments for Women
This study compares different treatments for overactive bladder in women in Taiwan. It aims to find the best approach to help control symptoms like frequent or urgent urination.
New Taipei CityAges 30–100 - NCT07082972RecruitingPhase 4
Study of splint therapy and Botox for jaw muscle pain
This trial compares two treatments—a dental splint and Botox injections into the jaw muscle (masseter)—to see which one better relaxes head and neck muscles in people with myofascial pain syndrome. It may help you if you have facial pain related to muscle tension.
Istanbul, VeznecilerAges 18–55 - NCT07377929Recruiting
Botox with prostate surgery for urinary symptoms
This trial tests whether adding Botox to standard prostate surgery (TURP or Aquablation) can better improve urinary symptoms in men. It is for men who are already planning to have both procedures.
Seattle, WashingtonAges 18 years+ - NCT06437899Enrolling by invitation
Numbing methods for Botox in the bladder for overactive bladder
This study compares two ways to numb the bladder before a Botox injection for overactive bladder: local anesthesia (numbing medicine in the bladder) versus sedoanalgesia (medication to relax and reduce pain). The goal is to see which method works better and makes patients more comfortable.
LeobenAges 18 years+
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Common questions
- Are there clinical trials for botox?
- Yes. Clin2 currently lists 44 recruiting botox studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a botox trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a botox trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.