Clin2
NCT07082972Possibly a fitRecruiting

Study of splint therapy and Botox for jaw muscle pain

Myofascial Pain Syndrome (MPS)Masticatory Muscle Pain

Treatments studied

Part of Bones, joints & muscles, Mouth & dental clinical trials.

This trial compares two treatments—a dental splint and Botox injections into the jaw muscle (masseter)—to see which one better relaxes head and neck muscles in people with myofascial pain syndrome. It may help you if you have facial pain related to muscle tension.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 4
Enrollment
56 people
Ages
18 years to 55 years
Study type
Interventional

Who can take part

  • You have been diagnosed with myofascial pain syndrome (muscle-related pain in the jaw or face).
  • You have no missing teeth.
  • You have not previously received treatment for a jaw joint problem (temporomandibular disorder).
  • Your jaw pain is not caused by a joint problem (arthrogenic disorder).
  • You are not pregnant, breastfeeding, or taking blood thinners, and you have no bleeding disorders, muscle or nerve diseases, or recent facial cosmetic treatments.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07867379Not yet recruiting· Phase 4
Botox vs steroid injections for facial muscle pain

This study compares two types of injections—Botox and a steroid called triamcinolone—to see which works better for facial pain caused by muscle knots (myofascial pain). If you are an adult with this type of facial pain, this trial may help find a treatment that offers longer-lasting relief.

Riyadh, Riyadh Region
NCT07640035Not yet recruiting· Early Phase 1
Botox for teeth grinding with digital bite analysis

This study tests whether Botox injections can help reduce teeth grinding and clenching (bruxism). The trial uses a digital bite analysis to measure how your teeth come together before and after treatment.

Bilecik, Bilecik
NCT07878780Not yet recruiting· Phase 2
MRI study of Botox for jaw muscle pain

This study uses MRI scans to see how Botox affects jaw muscle pain. It may help people with pain from jaw muscle spasms.

New York, New York
NCT07774884Not yet recruiting
Botulinum toxin with extra muscle injection for jaw pain

This study tests whether adding an injection into a deeper jaw muscle improves pain relief from botulinum toxin treatment for jaw muscle pain. It may help people with chronic jaw pain that worsens with chewing or other jaw movements.

Cairo, Cairo Governorate
NCT05720065Recruiting· Phase 2
Testing botulinum toxin A for jaw muscle pain

This trial studies whether botulinum toxin A (a type of muscle-relaxing medicine) can reduce jaw muscle pain and help explain why it happens. It focuses on people with specific jaw muscle pain patterns and tests outcomes after injection/biopsy.

Huddinge, Stockholm County
NCT06677216Enrolling by invitation
Botox for jaw muscle pain study

This study tests if Botox injections can reduce pain in the jaw muscles caused by a jaw joint disorder (TMD). If you have this type of pain and are interested in Botox treatment, you may be able to join.

Utrecht, Utrecht

Hear when a new Masticatory Muscle Pain trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.