Botox injections for trigeminal neuralgia pain
Part of Brain & nervous system, Mouth & dental clinical trials.
This study tests Botox (onabotulinumtoxinA) injections to reduce pain attacks in people with trigeminal neuralgia who haven't gotten enough relief from medication or don't want surgery. You must have frequent attacks (more than 10 per week) and be on a stable medication dose.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 or older
- You have trigeminal neuralgia (sharp, electric-shock-like face pain) diagnosed by a doctor
- You have more than 10 pain attacks per week
- You've tried at least 2 different medications for this pain without enough relief
- You are not a candidate for surgery, have already tried it without success, or do not want surgery
- Your pain medication dose has been the same for the past 2 weeks
- You are not pregnant or nursing, and do not have a neuromuscular disease or take aminoglycoside antibiotics
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests a Botox injection (HengLi®) to see if it can reduce facial pain from trigeminal neuralgia. It is for people whose pain is not well controlled by standard medications.
This trial tests if adding electroacupuncture to your current medication can better control trigeminal neuralgia pain and reduce side effects. You should already be taking carbamazepine or oxcarbazepine.
This trial tests whether adding electroacupuncture (a type of acupuncture with mild electric current) helps reduce facial pain in people with trigeminal neuralgia. It may help if you are already on carbamazepine medicine but still have pain.
This trial tests whether Botox injections can reduce jaw and face muscle pain in people with temporomandibular disorders (TMD). It is for those who have had moderate to severe pain for at least 3 months and have not received Botox recently.
This Phase 2 trial tests whether injecting incobotulinumtoxin-A near painful nerves can reduce nerve-type pain in the feet for people with diabetes. If you have lasting, fairly symmetrical pain in both feet, the injections may help calm the nerve pain signals.
This study tests whether a numbing spray applied inside the nose before Botox injections can reduce injection pain in people with chronic migraine. The goal is to make the treatment more comfortable without affecting how well it works.
Hear when a new Trigeminal Neuralgia trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.