Clinical trials
Breast cancer clinical trials
Cancer that forms in the cells of the breast, the most common cancer in women. We’re tracking 2,472 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07361562RecruitingPhase 1
Study of CGT4255 for advanced solid tumors with HER2 changes
This trial tests an oral drug called CGT4255 for people with advanced solid tumors that have certain changes in the HER2 gene or related proteins. It aims to see if the drug is safe and effective.
Grand Rapids, MichiganAges 18 years+ - NCT07644702Recruiting
Community health forums to increase breast cancer screening
This study invites rural and low-income women to join free community forums that teach about breast cancer screening and clinical trials. The goal is to help more women get mammograms (breast X-rays) and learn about research opportunities that might benefit their health.
Eau Claire, WisconsinAges 50–74 - NCT05910294Recruiting
Preventing and improving sexual health in early breast cancer
This study looks at ways to prevent and treat sexual discomfort in people with hormone-receptor positive breast cancer. It targets women who are not having current vaginal dryness or pain related to lower estrogen, and may help protect sexual comfort during cancer-related hormone treatment.
Basking Ridge, New JerseyAges 18 years+ - NCT06214195RecruitingPhase 3
Shengmai San to prevent heart damage from breast cancer therapy
This trial tests if a traditional Chinese medicine called Shengmai San can protect the heart during chemotherapy and targeted therapy for HER2-positive breast cancer. Patients take the supplement alongside standard treatment to see if it reduces the risk of heart problems.
Hangzhou, ZhejiangAges 18 years+ - NCT06904989Recruiting
Helping foot nerve pain from chemo with shoe inserts
This trial tests whether special shoe inserts can reduce foot pain and numbness caused by chemotherapy for breast cancer. It may help you feel better and walk more easily.
GothenburgAges 18 years+ - NCT07019233Recruiting
Can a pressure controller help with nerve pain from chemo?
This trial tests a device that applies real-time pressure to see if it can reduce numbness, tingling, or pain caused by a chemotherapy drug called albumin paclitaxel. It may help people starting this treatment for the first time.
TianjinAges 18–75 - NCT05825482Recruiting
Testing different breast surgery margin samples with a guidance tool
This study compares two ways surgeons take “margin” samples (tissue from the edge of the tumor area) during breast-conserving surgery for early breast cancer. It uses a guidance device to help collect these samples and aims to see which approach better supports safe, effective treatment.
Akron, OhioAges 18 years+ - NCT07341867RecruitingPhase 1
Dose changes for cancer treatment in people with Duffy null
This trial tests if changing the dose of certain chemotherapy drugs can help people with a genetic trait called Duffy null avoid side effects like low white blood cell counts. It is for people with multiple myeloma or triple-negative breast cancer starting specific treatments.
Boston, MassachusettsAges 18 years+ - NCT05325632RecruitingPhase 2
HER2 breast cancer vaccine plus chemo and targeted antibodies
This Phase 2 study tests a personalized immune-therapy vaccine made from your immune cells, given with weekly paclitaxel and HER2-targeted antibodies (trastuzumab and pertuzumab). It aims to improve treatment outcomes for people with HER2-positive breast cancer before standard local treatment (like surgery and radiation).
Tampa, FloridaAges 18 years+ - NCT06069115Recruiting
How radiation affects lung function in breast cancer patients
This study looks at how radiation therapy for breast cancer may affect your lungs over time. Researchers will measure lung function and see if problems develop, so they can better understand and protect patients.
Novosibirsk, Novosibirsk OblastAges 18 years+ - NCT06789653Recruiting
Using age-related proteins in early breast cancer
This study is testing a new way to use proteins in your blood that change with age to better understand early-stage breast cancer. It may help doctors personalize your care.
Chapel Hill, North CarolinaAges 22–66 - NCT07187726Recruiting
Trial to predict arm swelling risk during breast cancer radiation
This trial checks if telling you about your personal risk of arm swelling (based on a computer prediction) helps prevent it. You'll wear a compression sleeve during radiation and be monitored closely.
ArrasAges 18 years+ - NCT07225114RecruitingPhase 2
Better ultrasound imaging with contrast before biopsy
This trial tests a new, detailed ultrasound technique that uses a contrast agent (called Definity) to get clearer images of a suspicious area before a biopsy. It may help doctors better see the blood flow in the lesion, which could improve diagnosis.
Chapel Hill, North CarolinaAges 18 years+ - NCT07650305Recruiting
Pain Relief Methods After Breast Cancer Surgery
This trial compares two different nerve-blocking techniques (numbing methods) to reduce pain after breast cancer surgery. Both approaches aim to keep you comfortable during and after your operation.
CairoAges 18–65 - NCT07586319Enrolling by invitation
Surgery to improve survival in early-stage spread breast cancer
This study tests whether surgery to remove cancer spots can help people with breast cancer that has spread to a few places live longer. You would receive standard cancer medicines plus surgery if you qualify.
Lahore, Punjab ProvinceAges 18 years+ - NCT05111561RecruitingPhase 1
Testing a two-drug combo for RAS-mutant or triple negative breast cancer
This study tests a combination of two new drugs, ZEN003694 and binimetinib, for people with advanced solid tumors that have certain gene changes (like RAS mutations) or triple negative breast cancer. The goal is to see if this combination can shrink tumors or slow their growth.
Boston, MassachusettsAges 18 years+ - NCT03396341Recruiting
Surveys after genetic risk results for certain breast cancer genes
This study asks women to complete surveys after learning their genetic risk results for certain breast cancer–related gene changes. It helps researchers understand how people respond and what they think or feel after getting these results.
Boston, MassachusettsAges 25 years+ - NCT07238088Recruiting
Mammogram checkup and guidance for Puerto Rico
This trial helps women aged 40-74 in certain areas of Puerto Rico who are overdue for a mammogram. It offers counseling and resources to get screened for breast cancer.
San JuanAges 40–74 - NCT06022029RecruitingPhase 1
Study of injected ONM-501 alone or with cemiplimab for advanced cancers
This trial tests an injected study drug (ONM-501) alone or with another drug (cemiplimab) for people with advanced solid tumors or lymphomas that haven't responded to other treatments. It aims to find a safe dose and see if the combination helps shrink or control the cancer.
Los Angeles, CaliforniaAges 18 years+ - NCT06033287Recruiting
Real-world study of CDK4/6 inhibitors plus hormone therapy for advanced breast cancer
This study looks at how well CDK4/6 inhibitors combined with hormone therapy work in real-world settings for people with a certain type of advanced breast cancer (HR+/HER2-). It aims to understand the best treatment path and what happens next.
Changsha, HunanAges 18 years+ - NCT06888258Recruiting
Comparing two nerve blocks for pain after breast cancer surgery
This study compares two types of nerve blocks for pain relief after breast cancer surgery. It will help determine which block works better to reduce pain and the need for strong pain medicines after a mastectomy.
CairoAges 18–60 - NCT07046923RecruitingPhase 1
A study of LY4175408 for advanced cancer
This trial tests a new targeted drug (LY4175408) for people with certain advanced solid tumors (lung, endometrial, or triple negative breast cancer) who have already tried standard treatments. The goal is to see if the drug is safe and effective.
Stanford, CaliforniaAges 18 years+ - NCT07390448Recruiting
Comparing two pain block methods for mastectomy
This trial compares two nerve block techniques to control pain after breast cancer surgery. If you are having a mastectomy or breast-conserving surgery with lymph node removal, this study may help reduce your pain and improve recovery.
CairoAges 18–60 - NCT06712524Recruiting
Comparing surgery types for granulomatous mastitis
This study compares different surgical methods for treating granulomatous mastitis, a rare inflammatory breast condition. It aims to find which approach works best for patients who can safely have surgery.
Wuhan, HubeiAges 18 years+
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Common questions
- Are there clinical trials for breast cancer?
- Yes. Clin2 currently lists 2,472 recruiting breast cancer studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a breast cancer trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a breast cancer trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.