Clinical trials
Breast cancer clinical trials
Cancer that forms in the cells of the breast, the most common cancer in women. We’re tracking 2,466 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04371913Recruiting
Second chance breast-conserving treatment for certain breast recurrences
This trial studies a personalized plan to remove and re-treat a limited breast recurrence while trying to keep the breast. It may help people whose cancer came back in the same breast after prior breast-conserving treatment, with certain size and spread limits.
Brooklyn, New YorkAges 19–90 - NCT06694181Recruiting
Safe and explainable AI for heart, sepsis, and breast cancer patients
This trial uses artificial intelligence (AI) to create prediction models for three groups: cardiology patients, sepsis patients, and breast cancer patients. It aims to make these models safe and easy to understand for doctors.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07467330RecruitingPhase 3
Breast cancer trial: Adding capecitabine to standard treatment
This trial tests if adding a chemotherapy drug called capecitabine to the combination of dalpiciclib and hormone therapy works better than dalpiciclib and hormone therapy alone for advanced breast cancer that is hormone receptor-positive and HER2-negative. It is for people who have not had these treatments before.
Fuzhou, FujianAges 18 years+ - NCT06382818Recruiting
Personalized breast radiation based on risk and side effects
This trial tests whether radiation therapy can be personalized based on your risk of the cancer coming back and your risk of side effects from radiation. Depending on those factors, you may receive a tailored radiation plan that could be more or less intense.
MontpellierAges 18 years+ - NCT03124212Recruiting
Genetic testing guidance for inherited breast, ovarian, or colon cancer risk
This study helps people in Switzerland who already have a known inherited cancer gene change understand what it means for them and their family. It focuses on people with specific known mutations related to hereditary breast/ovarian cancer and Lynch syndrome.
Fribourg, Canton of FribourgAges 18 years+ - NCT07383649RecruitingPhase 2
Anti-CMV therapy for breast cancer with brain metastases
This trial tests a treatment targeting a common virus (CMV) in breast cancer that has spread to the brain. The goal is to see if anti-CMV therapy can shrink or slow these brain tumors.
Houston, TexasAges 18 years+ - NCT05134779Recruiting
Study aims to tailor cancer treatment to your biology
This study looks at how genes, the cancer environment, and your immune system interact to develop treatments that work better for people with breast cancer. It may help researchers learn why some treatments work for certain people and not others.
New York, New YorkAges 18–90 - NCT05450016Recruiting
Using photos and a computer to assess breast appearance after treatment
This study uses a computer (deep neural network) to judge how the breast looks after breast-conserving surgery or full breast reconstruction and radiation therapy. It may help doctors measure cosmetic results more consistently using photographs.
Mumbai, MaharashtraAges 19–80 - NCT05451784RecruitingPhase 1/Phase 2
PD-1 TIL therapy for advanced triple-negative breast cancer
This study tests an immune-cell treatment made from your tumor tissue. It aims to help people with advanced or metastatic triple-negative breast cancer by collecting PD-1–positive immune cells and giving them back after treatment.
BarcelonaAges 18 years+ - NCT07694986RecruitingPhase 2
Vaccine therapy for breast cancer that has spread to the brain and spinal cord
This trial tests a new type of vaccine (dendritic cells) injected directly into the spinal fluid, combined with either trastuzumab (if your breast cancer is HER2-positive) or nivolumab (if your breast cancer is HER2-negative). The goal is to see if this combination can better control breast cancer that has spread to the lining of the brain and spinal cord.
Tampa, FloridaAges 18 years+ - NCT07136753Recruiting
Study of radiotherapy effects on breast reconstruction
This study is looking at how radiotherapy affects women who have immediate breast reconstruction after mastectomy. The goal is to understand the changes and improve future care. Participants will have 3D imaging and answer questionnaires.
LondonAges 18 years+ - NCT06926868RecruitingPhase 2/Phase 3
Study of a new drug versus chemotherapy for advanced triple-negative breast cancer
This trial tests a new investigational drug called izalontamab brengitecan against standard chemotherapy for people with advanced triple-negative breast cancer who cannot receive immunotherapy. The goal is to see if the new drug works better at shrinking or slowing the cancer.
Hot Springs, ArkansasAges 18 years+ - NCT07630935Recruiting
Breast Cancer Risk Check for Night Shift Workers
This study helps women who work night shifts understand their personal breast cancer risk and get personalized advice to stay healthy. Researchers will review your health history and work schedule to create a customized care plan.
ParisAges 18 years+ - NCT05851053Recruiting
Study of heart function years after breast cancer treatment
This study checks how well your heart works long after breast cancer treatment. If you joined the earlier de BLOC-I study, you may be invited for follow-up to understand long-term heart effects.
GroningenAges Any age - NCT06245889RecruitingPhase 2
PET-Guided Therapy for Triple-Negative Breast Cancer
This trial tests whether a special PET scan can help guide the best combination of chemotherapy and immunotherapy before surgery for patients with triple-negative breast cancer. It aims to personalize treatment and improve outcomes.
Baltimore, MarylandAges 18 years+ - NCT06468566Recruiting
New imaging test for breast lumps using sound and light
This study tests a new kind of imaging that uses sound waves and light to tell if a breast lump is benign (not cancer) or malignant (cancer). It could help avoid unnecessary biopsies.
Wuhan, HubeiAges 18–85 - NCT06663228Recruiting
Faster breast biopsy analysis with mass spectrometry and AI
This trial uses a small mass spectrometer and artificial intelligence to quickly analyze breast tissue during a stereotactic biopsy. It aims to speed up detection and improve early diagnosis.
TaipeiAges 20–99 - NCT06991790Recruiting
Sacituzumab Govitecan and Toripalimab for First-Line Advanced Triple-Negative Breast Cancer
This trial tests a combination of two drugs—sacituzumab govitecan (a targeted chemotherapy) and toripalimab (an immunotherapy)—as the first treatment for advanced triple-negative breast cancer. The goal is to see if this pair works better than standard treatments, and to look for biomarkers that might predict who benefits most.
BeijingAges 18–75 - NCT07361562RecruitingPhase 1
Study of CGT4255 for advanced solid tumors with HER2 changes
This trial tests an oral drug called CGT4255 for people with advanced solid tumors that have certain changes in the HER2 gene or related proteins. It aims to see if the drug is safe and effective.
Grand Rapids, MichiganAges 18 years+ - NCT07644702Recruiting
Community health forums to increase breast cancer screening
This study invites rural and low-income women to join free community forums that teach about breast cancer screening and clinical trials. The goal is to help more women get mammograms (breast X-rays) and learn about research opportunities that might benefit their health.
Eau Claire, WisconsinAges 50–74 - NCT05910294Recruiting
Preventing and improving sexual health in early breast cancer
This study looks at ways to prevent and treat sexual discomfort in people with hormone-receptor positive breast cancer. It targets women who are not having current vaginal dryness or pain related to lower estrogen, and may help protect sexual comfort during cancer-related hormone treatment.
Basking Ridge, New JerseyAges 18 years+ - NCT06214195RecruitingPhase 3
Shengmai San to prevent heart damage from breast cancer therapy
This trial tests if a traditional Chinese medicine called Shengmai San can protect the heart during chemotherapy and targeted therapy for HER2-positive breast cancer. Patients take the supplement alongside standard treatment to see if it reduces the risk of heart problems.
Hangzhou, ZhejiangAges 18 years+ - NCT06904989Recruiting
Helping foot nerve pain from chemo with shoe inserts
This trial tests whether special shoe inserts can reduce foot pain and numbness caused by chemotherapy for breast cancer. It may help you feel better and walk more easily.
GothenburgAges 18 years+ - NCT07019233Recruiting
Can a pressure controller help with nerve pain from chemo?
This trial tests a device that applies real-time pressure to see if it can reduce numbness, tingling, or pain caused by a chemotherapy drug called albumin paclitaxel. It may help people starting this treatment for the first time.
TianjinAges 18–75
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Common questions
- Are there clinical trials for breast cancer?
- Yes. Clin2 currently lists 2,466 recruiting breast cancer studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a breast cancer trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a breast cancer trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.