Clinical trials
Bupivacaine clinical trials
Below are recruiting bupivacaine clinical trials, each written for real people, not researchers. We’re tracking 202 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05830630Recruiting
Methylene blue given during leg amputation surgery
This trial studies whether infusing methylene blue during above- or below-knee leg amputation can improve outcomes for people with poor blood flow to the legs. It targets patients having surgery under general anesthesia, while excluding those with certain allergies or blood clotting problems.
Tanta, Gharbia GovernorateAges 18 years+ - NCT05750992Recruiting
Ultrasound vs surgery guidance for numbing during C-section
This trial compares two ways of placing numbing medicine (with bupivacaine) during a planned C-section: an ultrasound-guided approach versus a surgical approach. It aims to find which method provides better pain control and comfort with fewer problems.
CairoAges 21–35 - NCT05543694RecruitingPhase 4
Testing epidural pain relief for labor
This study is testing how well a combination of two medicines (bupivacaine and lidocaine) works for epidural pain relief during early labor. The goal is to find the best dose to help manage labor pain.
Boston, MassachusettsAges 18–50 - NCT05425979Enrolling by invitationPhase 4
Compare numbing medicines for ankle blocks in foot surgery
This study tests which numbing medicine works faster for an ultrasound-guided ankle nerve block during foot surgery: mepivacaine or bupivacaine. It may help improve comfort by reducing how long it takes for the numbness to start.
Rochester, MinnesotaAges 18 years+ - NCT04930887RecruitingPhase 2
Numbing injection in the face to ease craniofacial pain
This trial tests whether an injection of a numbing medicine (bupivacaine) guided by an endoscope can reduce craniofacial pain. It may help people with certain headache or facial pain conditions by targeting the pain area more precisely.
Stanford, CaliforniaAges 18–80 - NCT04928352RecruitingPhase 3
Breathing numbing medicine during cleft palate surgery
This trial tests whether a breathing treatment (nebulized numbing medicine) can reduce pain during cleft palate repair in young children. It may help comfort your child after surgery when they are under general anesthesia.
Asyut, AssuitAges 1–7 - NCT04577690RecruitingPhase 4
PECS pain study for children getting a chest device implanted
This trial tests a pain-control method (PECS) during surgery for children who are having a small chest device implanted. It may help reduce discomfort during and after the operation.
Toronto, OntarioAges 3–18 - NCT04260854Enrolling by invitationPhase 1
Bupivacaine for pain control during skin surgery
This Phase 1 study tests bupivacaine, a numbing medicine, to see how well it controls pain during cutaneous (skin) surgery. It’s primarily looking at safety and how the medicine works for people undergoing the procedure.
Chicago, IllinoisAges 19 years+ - NCT03715517Recruiting
Spinal anesthesia to improve recovery after liver surgery
This trial studies whether using spinal/epidural anesthesia during liver tumor removal surgery can help people recover better and with less pain. It compares this approach to standard general anesthesia care to see if recovery is smoother.
Winnipeg, ManitobaAges 18 years+ - NCT07877974Recruiting
Nerve block for foot and ankle surgery pain relief
This study tests a numbing injection near the calf muscle to see how well it controls pain after foot or ankle surgery. It may help reduce the need for strong pain medicines after the operation.
Cairo, GovernorateAges 18–65 - NCT07878156RecruitingPhase 3
Numbing medicine for children having brain tumor surgery
This study tests whether adding a numbing medicine to the standard pain block can reduce pain after brain surgery in children. It may help children feel more comfortable and recover more smoothly.
CairoAges Up to 18 years - NCT07878533RecruitingPhase 2
Ear surgery pain relief with added medication
This study tests whether adding a sedative medicine to the numbing shot around the ear nerve can improve pain control during and after middle ear surgery. It aims to make the procedure more comfortable and reduce the need for strong painkillers.
MinyaAges 18–70 - NCT07855341RecruitingPhase 4
Nerve block study for hip replacement pain relief
This study tests two different amounts of a numbing medicine injected around the hip nerves before hip replacement surgery, to see if adding a steroid helps reduce pain after surgery. It aims to improve pain control and recovery.
Cairo, Cairo GovernorateAges 50–70 - NCT07467356RecruitingPhase 3
Nerve blocks for easier positioning before hip surgery
This study compares two different numbing injections (nerve blocks) to see which one helps you get into position more easily for spinal anesthesia before hip surgery. The goal is to make the procedure less painful and more comfortable.
Banhā, ElqalyoubeaAges 18 years+ - NCT06997016Enrolling by invitationPhase 4
Recovery program for living donor kidney transplant
This trial tests a special recovery program (ERAS) for people who get a kidney from a living donor. The program aims to help you heal faster and feel better after surgery.
Fort Worth, TexasAges 18 years+ - NCT04209504Recruiting
Nerve block study for one-sided breathing muscle weakness after shoulder surgery
This trial tests whether a longer-lasting nerve block during shoulder surgery can better manage pain and affect one-sided diaphragm (breathing muscle) weakness. It may help people having planned (first-time) shoulder surgery who are able to follow study pain-checks.
Durham, North CarolinaAges 18–80 - NCT03420638RecruitingPhase 4
Pain relief after tonsillectomy
This study tests a long-lasting numbing medicine (bupivacaine) injected during tonsillectomy to see if it helps reduce pain after surgery. It may offer better pain control than standard care.
Ann Arbor, MichiganAges 18 years+ - NCT06166628Recruiting
Comparing two procedures for knee osteoarthritis pain
This study compares two minimally invasive procedures—embolization (blocking blood flow) and nerve ablation (blocking pain signals)—to see which works better for knee osteoarthritis pain. If you have long-lasting knee pain and are considering knee replacement surgery, this trial may help find another option.
Kingston, OntarioAges 40 years+ - NCT06338865Recruiting
Lower pressure vs. standard pressure for laparoscopic gynecologic surgery
This trial compares using lower gas pressure during minimally invasive gynecologic surgery to the standard pressure. The goal is to see if lower pressure reduces pain and speeds recovery after surgery.
Los Angeles, CaliforniaAges 18 years+ - NCT06189781RecruitingPhase 4
Pain shot vs epidural for hip surgery in kids with cerebral palsy
This study compares a pain injection to epidural anesthesia for children with cerebral palsy having hip surgery. The goal is to see which method provides better pain control during and after the procedure.
Los Angeles, CaliforniaAges Up to 18 years - NCT07841184RecruitingPhase 4
Comparing two spinal anesthetics for prostate surgery
This study compares two types of spinal anesthesia (numbing medicine injected near the spine) to see which one works better for patients having TURP, a common prostate surgery. You might benefit from joining because it could help improve your recovery and comfort during the procedure.
Islamabad, FederalAges 40–90 - NCT07839195Enrolling by invitationPhase 2
Steroid injection after radiofrequency ablation for back and neck pain
This trial tests whether giving a corticosteroid injection right after a radiofrequency nerve ablation (a procedure that zaps nerve endings to reduce pain) can help prevent the temporary nerve irritation that sometimes happens after. It may help make your recovery more comfortable.
BangkokAges 18 years+ - NCT07826936RecruitingEarly Phase 1
Nerve block for severe abdominal pain in the emergency department
This trial tests whether a nerve block can provide better pain relief for severe abdominal pain that hasn't improved with standard pain medicine. It's for people who are not candidates for surgery and are in the emergency department or already in the hospital.
Orange, CaliforniaAges 18 years+ - NCT07794852Enrolling by invitation
Ultrasound-guided spinal anesthesia for prostate surgery
This study tests a new way to give spinal anesthesia (numbing medicine injected in your back) for prostate surgery. It uses ultrasound to measure the fluid space around your spinal cord to find the right dose, which may make the anesthesia safer and more effective.
IstanbulAges 40 years+
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Common questions
- Are there clinical trials for bupivacaine?
- Yes. Clin2 currently lists 202 recruiting bupivacaine studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a bupivacaine trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a bupivacaine trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.